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Autor:
Adia Shy, Frank Porreca, Theodore J. Price, Marina N. Asiedu, Ohannes K. Melemedjian, Dipti V. Tillu, Raul Sanoja, Bryce Bodell, Sourav Ghosh
Publikováno v:
The Journal of Neuroscience. 31:6646-6653
Sensitization of the pain pathway is believed to promote clinical pain disorders. We hypothesized that the persistence of a sensitized state in the spinal dorsal horn might depend on the activity of protein kinase M ζ (PKMζ), an essential mechanism