Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Bryant S. Fujimoto"'
Autor:
James Kim, Shihan Xu, Seung‐Ryoung Jung, Alya Nguyen, Yuanhua Cheng, Mengxia Zhao, Bryant S. Fujimoto, Wyatt Nelson, Perry Schiro, Jeffrey L. Franklin, James N. Higginbotham, Robert J. Coffey, Min Shi, Lucia N. Vojtech, Florian Hladik, Muneesh Tewari, John Tigges, Ionita Ghiran, Tijana Jovanovic‐Talisman, Louise C. Laurent, Saumya Das, Olesia Gololobova, Kenneth W. Witwer, Tuoye Xu, Al Charest, Kendall Van Keuren Jensen, Robert L. Raffai, Jennifer C. Jones, Joshua A. Welsh, John P. Nolan, Daniel T. Chiu
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 8, Pp n/a-n/a (2024)
Abstract High‐sensitivity flow cytometers have been developed for multi‐parameter characterization of single extracellular vesicles (EVs), but performance varies among instruments and calibration methods. Here we compare the characterization of i
Externí odkaz:
https://doaj.org/article/7ea6b425e4f14da5b65bb5379df9a944
Autor:
Alison M Thompson, Jordan L Smith, Luke D Monroe, Jason E Kreutz, Thomas Schneider, Bryant S Fujimoto, Daniel T Chiu, Jerald P Radich, Amy L Paguirigan
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196801 (2018)
Cancer is a heterogeneous disease, and patient-level genetic assessments can guide therapy choice and impact prognosis. However, little is known about the impact of genetic variability within a tumor, intratumoral heterogeneity (ITH), on disease prog
Externí odkaz:
https://doaj.org/article/ff31e625eb914d559a7bbb87f0ea1654
Autor:
Yifei Jiang, Haobin Chen, Luca A Andronico, Seung-Ryoung Jung, Bryant S. Fujimoto, Daniel T. Chiu, Lucia Vojtech
Publikováno v:
Angew Chem Int Ed Engl
Here, we describes a method for high-throughput counting and superresolution mapping of surface proteins on exosomes, using a combination of a single-molecule sensitive flow technique and an adaptive superresolution imaging method. Exosomes stained w
Autor:
Luca A Andronico, Seung-Ryoung Jung, Lucia Vojtech, Bryant S. Fujimoto, Daniel T. Chiu, Yifei Jiang
Publikováno v:
Anal Chem
Extracellular vesicles (EVs) are membranous particles released by most cells in our body, and which are involved in many cell-to-cell signaling processes. Given the nanometer sizes and heterogeneity of EVs, highly sensitive methods with single-molecu
Autor:
Daniel T. Chiu, Halia Haynes, Jeannette P. Staheli, Jason E. Kreutz, Kara Shibley, Yuling Qin, Thomas Schneider, Bryant S. Fujimoto, Qiongzheng Hu, Gloria S. Yen, Jingang Wang, Andrew Wu, Bob Weng, Qinghua Feng, Jiasi Wang, Rachel L. Winer
Publikováno v:
Anal Chem
Cervical cancer is the fourth-leading cause of cancer deaths among women worldwide and most cases occur in developing countries. Detection of high-risk (HR) HPV, the etiologic agent of cervical cancer, is a primary screening method for cervical cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b6abb4a97b049d5f71355f9cfa15e4
https://europepmc.org/articles/PMC8020467/
https://europepmc.org/articles/PMC8020467/
Publikováno v:
Current Opinion in Chemical Biology. 39:64-73
Quantitative microscopy is needed to understand reactions or phenomena carried out by biological molecules such as enzymes, receptors, and membrane-localized proteins. Counting the biomolecules of interest in single organelles or cellular compartment
Autor:
Wei-feng Fang, Shihan Xu, Perry G. Schiro, Jiasi Wang, Hui-Min Yu, Daniel T. Chiu, Bryant S. Fujimoto, Eleanor S. Johnson, Li Wu, Jui-Lin Chen, Mengxia Zhao, Yuling Qin
Publikováno v:
Anal Chem
Isolation and analysis of circulating tumor cells (CTCs) from the blood of patients at risk of metastatic cancers is a promising approach to improving cancer treatment. However, CTC isolation is difficult due to low CTC abundance and heterogeneity. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f971e5d06386dd8d2f6612e6ebcc3bbb
https://europepmc.org/articles/PMC9847251/
https://europepmc.org/articles/PMC9847251/
We present a method to determine the concentration of nucleic acids in a sample by partitioning it into droplets with a nonuniform volume distribution. This digital PCR method requires no special equipment for partitioning, unlike other methods that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b4146ecc79a7a70f5fbb9ae1d84ae7
https://europepmc.org/articles/PMC6383768/
https://europepmc.org/articles/PMC6383768/
Autor:
Rui Han, Daniel T. Chiu, Yu Rong, Jiangbo Yu, Chun-Ting Kuo, Wei Sun, Xing-Hua Zhou, Seung-Ryoung Jung, Yifei Jiang, Bryant S. Fujimoto
Publikováno v:
Analytical chemistry. 90(10)
We describe here a flow platform for quantifying the number of biomolecules on individual fluorescent nanoparticles. The platform combines line-confocal fluorescence detection with near nanoscale channels (1–2 µm in width and height) to achieve hi
Autor:
Wei Sun, Yu Rong, Chun-Ting Kuo, Bryant S. Fujimoto, Hongshang Peng, Daniel T. Chiu, Jiangbo Yu
Publikováno v:
Analytical chemistry. 89(11)
Multiplexed optical encoding is emerging as a powerful technique for high-throughput cellular analysis and molecular assays. Most of the developed optical barcodes, however, either suffer from large particle size or are incompatible with most commerc