Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Bryant G Darnay"'
Autor:
Betty Lamothe, Yunju Lai, Lana Hur, Natalia Martin Orozco, Jing Wang, Alejandro D Campos, Min Xie, Michael D Schneider, Cynthia R Lockworth, Jared Jakacky, Diep Tran, Michael Ho, Sity Dawud, Chen Dong, Hui-Kuan Lin, Peter Hu, Zeev Estrov, Carlos E Bueso-Ramos, Bryant G Darnay
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51228 (2012)
Previous studies of the conditional ablation of TGF-β activated kinase 1 (TAK1) in mice indicate that TAK1 has an obligatory role in the survival and/or development of hematopoietic stem cells, B cells, T cells, hepatocytes, intestinal epithelial ce
Externí odkaz:
https://doaj.org/article/f98ab889e1f742eb83b60ac8a1485b44
Autor:
Hiroaki Kimura, Kin Ming Kwan, Zhaoping Zhang, Jian Min Deng, Bryant G Darnay, Richard R Behringer, Takashi Nakamura, Benoit de Crombrugghe, Haruhiko Akiyama
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3174 (2008)
Bone mass is maintained by continuous remodeling through repeated cycles of bone resorption by osteoclasts and bone formation by osteoblasts. This remodeling process is regulated by many systemic and local factors.We identified collagen triple helix
Externí odkaz:
https://doaj.org/article/9cf2c279f5ca4afaa8078c2aa3d54647
Autor:
Michael G. Rosenblum, Bryant G. Darnay, Philip E. Thorpe, Nora M. Navone, Charles R. Sikes, Ann T. Poblenz, Khalid A. Mohamedali
The pathophysiology of tumor growth following skeletal metastases and the poor response of this type of lesion to therapeutic intervention remains incompletely understood. Vascular endothelial growth factor (VEGF)-A and its receptors play a role in b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da3be43809ff188551cbbd5aacc00d1
https://doi.org/10.1158/0008-5472.c.6494972
https://doi.org/10.1158/0008-5472.c.6494972
Autor:
Garth Powis, Eric Jonasch, Federico A. Monzon, Jose Karam, Thai H. Ho, Mena Abdelmelek, Galina Kiriakova, Bryant G. Darnay, Robert Lemos, Vuvi Nguyen, Mei Yee Koh
Clear-cell renal cell cancer (CRCC) is initiated typically by loss of the tumor-suppressor VHL, driving constitutive activation of hypoxia-inducible factor-1 (HIF1) and HIF2. However, whereas HIF1 has a tumor-suppressor role, HIF2 plays a distinct ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da13a9a4aec4ec75dddb7e18fbfd89f9
https://doi.org/10.1158/0008-5472.c.6506001
https://doi.org/10.1158/0008-5472.c.6506001
Autor:
Michael G. Rosenblum, Bryant G. Darnay, Philip E. Thorpe, Nora M. Navone, Charles R. Sikes, Ann T. Poblenz, Khalid A. Mohamedali
Supplementary Figure 2 from Inhibition of Prostate Tumor Growth and Bone Remodeling by the Vascular Targeting Agent VEGF121/rGel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a0548d034516cab145575cf6120866
https://doi.org/10.1158/0008-5472.22366061
https://doi.org/10.1158/0008-5472.22366061
Autor:
Michael G. Rosenblum, Bryant G. Darnay, Philip E. Thorpe, Nora M. Navone, Charles R. Sikes, Ann T. Poblenz, Khalid A. Mohamedali
Supplementary Figure 1 from Inhibition of Prostate Tumor Growth and Bone Remodeling by the Vascular Targeting Agent VEGF121/rGel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24473104d6866d2f11763b06d00135c1
https://doi.org/10.1158/0008-5472.22366064.v1
https://doi.org/10.1158/0008-5472.22366064.v1
Autor:
Garth Powis, Eric Jonasch, Federico A. Monzon, Jose Karam, Thai H. Ho, Mena Abdelmelek, Galina Kiriakova, Bryant G. Darnay, Robert Lemos, Vuvi Nguyen, Mei Yee Koh
Supplemental methods. A, B) Sequences for the A) P117 Luc, and B) P117 HRE reporters containing the HAF binding site, the hypoxia responsive element (HRE) and the HIF ancillary sequence (HAS), with the restriction enzyme sites used for ligation into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92cd78c5b212858b1a206297b3195499
https://doi.org/10.1158/0008-5472.22402158.v1
https://doi.org/10.1158/0008-5472.22402158.v1
Autor:
Michael G. Rosenblum, Bryant G. Darnay, Philip E. Thorpe, Nora M. Navone, Charles R. Sikes, Ann T. Poblenz, Khalid A. Mohamedali
Supplementary Figure 3 from Inhibition of Prostate Tumor Growth and Bone Remodeling by the Vascular Targeting Agent VEGF121/rGel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5416a038818563ee34cfec60b29bbd33
https://doi.org/10.1158/0008-5472.22366058.v1
https://doi.org/10.1158/0008-5472.22366058.v1
Autor:
Lucia Cabal-Hierro, Lorea J Ugarte-Gil, Noelia Artime, Miguel A. Prado, Bryant G. Darnay, Pedro Casado, J. Iglesias, Pedro S. Lazo, Belén Fernández-García
Publikováno v:
Oncotarget
Tumor Necrosis Factor (TNF) interacts with two receptors known as TNFR1 and TNFR2. TNFR1 activation may result in either cell proliferation or cell death. TNFR2 activates Nuclear Factor-kappaB (NF-kB) and c-Jun N-terminal kinase (JNK) which lead to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5111960f124f1dd938eaada54de703f
https://doi.org/10.18632/oncotarget.1492
https://doi.org/10.18632/oncotarget.1492
Publikováno v:
Molecular and Cellular Biology
Transforming growth factor β (TGF-β)-activated kinase 1 (TAK1), a mitogen-activated protein 3 (MAP3) kinase, plays an essential role in inflammation by activating the IκB kinase (IKK)/nuclear factor κB (NF-κB) and stress kinase (p38 and c-Jun N-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d270d97e7ff05e850596cd5d4d0c3f
https://doi.org/10.1128/mcb.01225-12
https://doi.org/10.1128/mcb.01225-12