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A glutamate concentration‐biased allosteric modulator potentiates NMDA‐induced ion influx in neurons
Autor:
Blaise M. Costa, Lina Cortés Kwapisz, Brittney Mehrkens, Douglas N. Bledsoe, Bryanna N. Vacca, Tullia V. Johnston, Rehan Razzaq, Dhanasekaran Manickam, Bradley G. Klein
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 5, Pp n/a-n/a (2021)
Abstract Precisely controlled synaptic glutamate concentration is essential for the normal function of the N‐methyl D‐aspartate (NMDA) receptors. Atypical fluctuations in synaptic glutamate homeostasis lead to aberrant NMDA receptor activity that
Externí odkaz:
https://doaj.org/article/af4e8464cbf4484c997b749172315022
Autor:
Rehan Razzaq, Bradley G. Klein, Blaise M. Costa, Tullia V. Johnston, Bryanna N. Vacca, Douglas N. Bledsoe, Dhanasekaran Manickam, Lina Cortés Kwapisz, Brittney Mehrkens
Publikováno v:
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 9, Iss 5, Pp n/a-n/a (2021)
Pharmacology Research & Perspectives, Vol 9, Iss 5, Pp n/a-n/a (2021)
Precisely controlled synaptic glutamate concentration is essential for the normal function of the N‐methyl D‐aspartate (NMDA) receptors. Atypical fluctuations in synaptic glutamate homeostasis lead to aberrant NMDA receptor activity that results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7040629e3e67dff531be67cd53f89f3
https://doi.org/10.1002/prp2.859
https://doi.org/10.1002/prp2.859