Výsledky vyhledávání - "Bryana N. Harris"

Dynamic map illuminates Hippo to cMyc module crosstalk driving cardiomyocyte proliferation

Autor: Bryana N. Harris, Laura A. Woo, R. Noah Perry, Mete Civelek, Matthew J. Wolf, Jeffrey J. Saucerman

Cardiac diseases are characterized by the inability of adult mammalian hearts to overcome the loss of cardiomyocytes (CMs). Current knowledge in cardiac regeneration lacks a clear understanding of the molecular systems determining whether CMs will pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d7c597c2264a1e9b3ecb5b46913897f
https://doi.org/10.1101/2022.10.11.511763

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Human Induced Pluripotent Stem Cell Encapsulation Geometry Impacts Three-Dimensional Developing Human Engineered Cardiac Tissue Functionality

Autor: Morgan E. Ellis, Bryana N. Harris, Mohammadjafar Hashemi, B. Justin Harvell, Michaela Z. Bush, Emma E. Hicks, Ferdous B. Finklea, Eric M. Wang, Ravikiran Nataraj, Nathan P. Young, Irene C. Turnbull, Elizabeth A. Lipke

Publikováno v: Tissue engineering. Part A. 28(23-24)

Cardiac tissue engineering has been working to alleviate the immense burden of cardiovascular disease for several decades. To improve cardiac tissue homogeneity and cardiomyocyte (CM) maturation, in this study, we investigated altering initial encaps

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c4c5b22ff36858e8452aef7483c149
https://pubmed.ncbi.nlm.nih.gov/36170590

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Abstract P457: Systems Analysis To Understand The Impact Of The CDK Module On Cardiomyocyte Proliferation

Autor: Laura A. Woo, Bryana N Harris, Jeffrey J. Saucerman

Publikováno v: Circulation Research. 129

Rationale: Heart failure is caused by the inability of adult mammalian hearts to overcome the loss of cardiomyocytes (CMs). This is due partly to the limited proliferative capacity of CMs, which exit the cell cycle and do not undergo cell division. C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b5c12890458b036cc71decde5feed47
https://doi.org/10.1161/res.129.suppl_1.p457

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Fundamentals of integrated ferrohydrodynamic cell separation in circulating tumor cell isolation

Autor: Bryana N. Harris, Petros Nikolinakos, Mary Egan, Travis Laver, Wujun Zhao, Jamie Hodgson, Leidong Mao, Yang Liu, Anastacia Bankey, Kristina Meichner, Jonathan R. Murrow, Rui Cheng

Publikováno v: Lab Chip

Methods to separate circulating tumor cells (CTCs) from blood samples were intensively researched in order to understand the metastatic process and develop corresponding clinical assays. However current methods faced challenges that stemmed from CTCs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68eb3faf8c55ea44c8c77cda61d3123b
https://pubmed.ncbi.nlm.nih.gov/33720269

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Tumor antigen-independent and cell size variation-inclusive enrichment of viable circulating tumor cells

Autor: Leidong Mao, Ana Bankey, Rui Cheng, Jin Xie, Haythem Ali, Jonathan R. Murrow, Bryana N. Harris, Jamie Hodgson, Melissa Davis, Petros Nikolinakos, Mary Egan, Wujun Zhao, Brittany D. Jenkins, Kristina Meichner, Weizhong Zhang, Lisa A. Newman, Yang Liu

Publikováno v: Lab Chip

Isolation of circulating tumor cells (CTCs) from blood provides a minimally-invasive alternative into the basic understanding, diagnosis and prognosis of metastatic cancers. The roles and clinical values of CTCs are under intensive investigation, yet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8e123fd6d10ce93102f0ee785b1fcb
https://europepmc.org/articles/PMC6590080/

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