Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Bryan Zimdahl"'
Autor:
Kyle Spinler, Jeevisha Bajaj, Takahiro Ito, Bryan Zimdahl, Michael Hamilton, Armin Ahmadi, Claire S. Koechlein, Nikki Lytle, Hyog Young Kwon, Ferdous Anower-E-Khuda, Hao Sun, Allen Blevins, Joi Weeks, Marcie Kritzik, Jan Karlseder, Mark H. Ginsberg, Pyong Woo Park, Jeffrey D. Esko, Tannishtha Reya
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Identifying leukaemia stem cells (LSC) and defining how they drive tumourigenesis might aid in the treatment of disease. Here, the authors show that a reporter Musashi 2 can serve as a platform to effectively identify leukemic stem cells and it is us
Externí odkaz:
https://doaj.org/article/9cff1956974c4fd4bec74dfa1770589a
Autor:
Claire S. Koechlein, Jeffrey R. Harris, Timothy K. Lee, Joi Weeks, Raymond G. Fox, Bryan Zimdahl, Takahiro Ito, Allen Blevins, Seung-Hye Jung, John P. Chute, Amit Chourasia, Markus W. Covert, Tannishtha Reya
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
It is difficult to image haematopoietic stem cells (HSC) in their niche. Here, the authors present a new high-throughput computational approach to visualise HSCs in vivoat a high spatial and temporal resolution and also use a Msi2-reporter to label e
Externí odkaz:
https://doaj.org/article/eb98c9dbcd7d47d28ac28ab4c7bfb28b
Autor:
Cheng Liu, Vivien W. Chan, Stephen J. Forman, Christine E. Brown, Saul J. Priceman, Binnaz K. Staley, Lian-xing Liu, Pengbo Zhang, Javier F. Morales, Yoko Nakano, Lu Jin, Juan Diaz, Pei Wang, Su Yan, Bin Liu, Lucas H. Horan, Neal Cheng, Jingwei Lu, Bryan Zimdahl, Zhiyuan Yang, Shon Green, Li Long, Jingyi Xiang, Yiyang Xu, Hong Liu
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5abef1545c442ba0fdb71d1f5c7a3246
https://doi.org/10.1158/1078-0432.22467768.v1
https://doi.org/10.1158/1078-0432.22467768.v1
Autor:
Cheng Liu, Vivien W. Chan, Stephen J. Forman, Christine E. Brown, Saul J. Priceman, Binnaz K. Staley, Lian-xing Liu, Pengbo Zhang, Javier F. Morales, Yoko Nakano, Lu Jin, Juan Diaz, Pei Wang, Su Yan, Bin Liu, Lucas H. Horan, Neal Cheng, Jingwei Lu, Bryan Zimdahl, Zhiyuan Yang, Shon Green, Li Long, Jingyi Xiang, Yiyang Xu, Hong Liu
Supplementary Figure S1. Epitope mapping of clones A-D by alanine scanning mutagenesis. Supplementary Figure S2. Analysis of the selectivity of ET1402L1 (clone B) towards AFP158. Supplementary Figure S3. Analysis of the potential risk for cross-prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c65678d4587c80c4da9af329161540b
https://doi.org/10.1158/1078-0432.22467771.v1
https://doi.org/10.1158/1078-0432.22467771.v1
Autor:
Cheng Liu, Vivien W. Chan, Stephen J. Forman, Christine E. Brown, Saul J. Priceman, Binnaz K. Staley, Lian-xing Liu, Pengbo Zhang, Javier F. Morales, Yoko Nakano, Lu Jin, Juan Diaz, Pei Wang, Su Yan, Bin Liu, Lucas H. Horan, Neal Cheng, Jingwei Lu, Bryan Zimdahl, Zhiyuan Yang, Shon Green, Li Long, Jingyi Xiang, Yiyang Xu, Hong Liu
Figure Legends for Sup. Figures 1-9 and Sup. Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23f7ef647d186810848333c6c90edcc
https://doi.org/10.1158/1078-0432.22467774
https://doi.org/10.1158/1078-0432.22467774
Autor:
Cheng Liu, Vivien W. Chan, Stephen J. Forman, Christine E. Brown, Saul J. Priceman, Binnaz K. Staley, Lian-xing Liu, Pengbo Zhang, Javier F. Morales, Yoko Nakano, Lu Jin, Juan Diaz, Pei Wang, Su Yan, Bin Liu, Lucas H. Horan, Neal Cheng, Jingwei Lu, Bryan Zimdahl, Zhiyuan Yang, Shon Green, Li Long, Jingyi Xiang, Yiyang Xu, Hong Liu
Purpose: The majority of tumor-specific antigens are intracellular and/or secreted and therefore inaccessible by conventional chimeric antigen receptor (CAR) T-cell therapy. Given that all intracellular/secreted proteins are processed into peptides a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059189502e37618c9d1888723a151675
https://doi.org/10.1158/1078-0432.c.6526737
https://doi.org/10.1158/1078-0432.c.6526737
Autor:
Pengcheng He, Haibo Liu, Bryan Zimdahl, Jie Wang, Minna Luo, Qi Chang, Fangzhou Tian, Fan Ni, Duo Yu, Huasheng Liu, Limei Chen, Huaiyu Wang, Mei Zhang, Stephan A. Grupp, Cheng Liu
Publikováno v:
Journal of cancer research and clinical oncology.
A barrier to widespread adoption of chimeric antigen receptor (CAR) T-cell therapy is toxicity. To address this, we recently developed a novel antibody-T-cell receptor (AbTCR) platform (trademarked as ARTEMISWe generated ET019003 T cells, which are a
Autor:
Nikki K. Lytle, Hyog Young Kwon, Michael Hamilton, Jeevisha Bajaj, Ferdous Anower-E-Khuda, Tannishtha Reya, Mark H. Ginsberg, Jeffrey D. Esko, Bryan Zimdahl, Armin Ahmadi, Kyle R. Spinler, Joi Weeks, Jan Karlseder, Claire S. Koechlein, Marcie Kritzik, Hao Sun, Pyong Woo Park, Allen Blevins, Takahiro Ito
Publikováno v:
Nature communications, vol 11, iss 1
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Intratumoral heterogeneity is a common feature of many myeloid leukemias and a significant reason for treatment failure and relapse. Thus, identifying the cells responsible for residual disease and leukemia re-growth is critical to better understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d060c5584d0922de3b8568c04b179d6
https://escholarship.org/uc/item/7vk3p3vd
https://escholarship.org/uc/item/7vk3p3vd
Autor:
Stephan A. Grupp, Cheng Liu, Bryan Zimdahl, Horan Lucas, Pengbo Zhang, Hong Liu, David M. Barrett, Yiyang Xu, Jingwei Lu, Liu Lianxing, Vivien W. Chan, Shon Green, Javier Morales, Zhiyuan Yang
Publikováno v:
Cell Discovery
Cell Discovery, Vol 4, Iss 1, Pp 1-13 (2018)
Cell Discovery, Vol 4, Iss 1, Pp 1-13 (2018)
The clinical use of genetically modified T-cell therapies has led to unprecedented response rates in leukemia and lymphoma patients treated with anti-CD19 chimeric antigen receptor (CAR)-T. Despite this clinical success, FDA-approved T-cell therapies
Publikováno v:
Cancer research, vol 75, iss 5
Asymmetric division is an evolutionarily conserved process that generates daughter cells with different fates through the unequal partitioning of fate determinants. While asymmetric division is critically important in generating diversity during deve