Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Bryan William Davies"'
Publikováno v:
Protein Sci
The beta hairpin motif is a ubiquitous protein structural motif that can be found in molecules across the tree of life. This motif, which is also popular in synthetically designed proteins and peptides, is known for its stability and adaptability to
Publikováno v:
Microbiology. 168
Microcins are an understudied and poorly characterized class of antimicrobial peptides. Despite the existence of only 15 examples, all identified from the Enterobacteriaceae , microcins display diversity in sequence, structure, target cell uptake, cy
Publikováno v:
Microbiology (Reading, England). 168(4)
Microcins are an understudied and poorly characterized class of antimicrobial peptides. Despite the existence of only 15 examples, all identified from the
Publikováno v:
Proceedings of the National Academy of Sciences. 117:27620-27626
The extracellular polysaccharide capsule of Klebsiella pneumoniae resists penetration by antimicrobials and protects the bacteria from the innate immune system. Host antimicrobial peptides are inactivated by the capsule as it impedes their penetratio
Autor:
Jiri Perutka, Peng Geng, Andrew D. Ellington, Jeffrey E. Barrick, Bryan William Davies, J. Elijah Powell, Sean P. Leonard, Richard D. Horak, Nancy A. Moran, Luke C. Heckmann
Publikováno v:
Science. 367:573-576
Inducing immune bee genes Honey bees are prone to parasitism by the Varroa mite, which is a vector for several bee pathogens. However, honey bees are also host to the symbiotic gut bacterium Snodgrassella alvi. Leonard et al. engineered S. alvi to pr
Publikováno v:
Methods in Molecular Biology ISBN: 9781071616888
Peptide macrocycles exhibit great ability to inhibit bacterial growth making them a promising new avenue for antimicrobial discovery. Surface Localized Antimicrobial Display (SLAY) is a platform allowing the high-throughput screening of large peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9471c93b50b891e6e708df4eed18d71
https://doi.org/10.1007/978-1-0716-1689-5_15
https://doi.org/10.1007/978-1-0716-1689-5_15
Autor:
Bryan William Davies, Orhi Esarte Palomero, Bradley J. Voss, Ashley L. Cunningham, M. Stephen Trent
Publikováno v:
Antimicrob Agents Chemother
Otilonium bromide is a poorly absorbed oral medication used to control irritable bowel syndrome. It is thought to act as a muscle relaxant in the intestine. Here, we show that otilonium bromide has broad-spectrum antibacterial and antifungal activity
Autor:
Bryan William Davies, Justin R Randall
Publikováno v:
Curr Opin Microbiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37b5d145f6ed9490b12e0cd40d068db
https://europepmc.org/articles/PMC8463434/
https://europepmc.org/articles/PMC8463434/
Autor:
Alexander A. Crofts, Ashley L. Ciosek, Alexandra R. Mey, Heidi A. Butz, Bryan William Davies, Shelley M. Payne
Publikováno v:
mBio
mBio, Vol 12, Iss 1 (2021)
mBio, Vol 12, Iss 1 (2021)
Vibrio cholerae, a Gram-negative bacterium, is a natural inhabitant of the aqueous environment. However, once ingested, this bacterium can colonize the human host and cause the disease cholera.
CsrA is a posttranscriptional global regulator in V
CsrA is a posttranscriptional global regulator in V
Publikováno v:
mSphere, Vol 5, Iss 6 (2020)
Pathogenic strains of Vibrio cholerae require careful regulation of horizontally acquired virulence factors that are largely located on horizontally acquired genomic islands (HAIs). While TsrA, a Vibrionaceae-specific protein, is known to regulate th