Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Bryan W. Day"'
Autor:
Juliana Muller Bark, Avinash V. Karpe, James D. Doecke, Paul Leo, Rosalind L. Jeffree, Benjamin Chua, Bryan W. Day, David J. Beale, Chamindie Punyadeera
Publikováno v:
Cancer Medicine, Vol 12, Iss 10, Pp 11427-11437 (2023)
Abstract Background Despite aggressive treatment, more than 90% of glioblastoma (GBM) patients experience recurrences. GBM response to therapy is currently assessed by imaging techniques and tissue biopsy. However, difficulties with these methods may
Externí odkaz:
https://doaj.org/article/bf2d3199e1af4d7b9ff4a2375a3e5b34
Autor:
Georgia K. B. Halkett, Lauren J. Breen, Melissa Berg, Rebecca Sampson, Hao-Wen Sim, Hui K. Gan, Benjamin Y. Kong, Anna K. Nowak, Bryan W. Day, Rosemary Harrup, Melissa James, Frank Saran, Brett Mcfarlane, Chris Tse, Eng-Siew Koh
Publikováno v:
Current Oncology, Vol 29, Iss 12, Pp 9928-9955 (2022)
The aim of this project was to determine research priorities, barriers, and enablers for adult primary brain tumour research in Australia and New Zealand. Consumers, health professionals, and researchers were invited to participate in a two-phase mod
Externí odkaz:
https://doaj.org/article/6cd87a96459d43ed8dda66d8c3a38599
Autor:
Ariadna Recasens, Sean J. Humphrey, Michael Ellis, Monira Hoque, Ramzi H. Abbassi, Brianna Chen, Mitchell Longworth, Elise J. Needham, David E. James, Terrance G. Johns, Bryan W. Day, Michael Kassiou, Pengyi Yang, Lenka Munoz
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-16 (2021)
Abstract Both tumour suppressive and oncogenic functions have been reported for dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A). Herein, we performed a detailed investigation to delineate the role of DYRK1A in glioblastoma. Our
Externí odkaz:
https://doaj.org/article/0a8dca1bb09e4683a7fb6162b88375d9
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background Approximately 80% of brain tumours are gliomas. Despite treatment, patient mortality remains high due to local metastasis and relapse. It has been shown that transferrin-functionalised porous silicon nanoparticles (Tf@pSiNPs) can
Externí odkaz:
https://doaj.org/article/77a1a454b16b4883bca265869f1d0b2f
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background The traditional concept that heritability occurs exclusively from the transfer of germline-restricted genetics is being challenged by the increasing accumulation of evidence confirming the existence of experience-dependent transge
Externí odkaz:
https://doaj.org/article/b3b5e4d16edf40ef888e6eefe7baed43
Autor:
Mengnan Li, Shin-ya Nishio, Chie Naruse, Meghan Riddell, Sabrina Sapski, Tatsuya Katsuno, Takao Hikita, Fatemeh Mizapourshafiyi, Fiona M. Smith, Leanne T. Cooper, Min Goo Lee, Masahide Asano, Thomas Boettger, Marcus Krueger, Astrid Wietelmann, Johannes Graumann, Bryan W. Day, Andrew W. Boyd, Stefan Offermanns, Shin-ichiro Kitajiri, Shin-ichi Usami, Masanori Nakayama
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
While biallelic mutations of the SLC26A4 gene cause non-syndromic hearing loss with enlarged vestibular aqueducts or Pendred syndrome, a considerable number of patients carry mono-allelic mutations. Here the authors identify EPHA2 as another causativ
Externí odkaz:
https://doaj.org/article/2394b397faac4471be86a22fa110d8db
Autor:
Juliana Müller Bark, Arutha Kulasinghe, Gunter Hartel, Paul Leo, Majid Ebrahimi Warkiani, Rosalind L. Jeffree, Benjamin Chua, Bryan W. Day, Chamindie Punyadeera
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioblastoma (GBM) is the most common and aggressive type of tumour arising from the central nervous system. GBM remains an incurable disease despite advancement in therapies, with overall survival of approximately 15 months. Recent literature has hi
Externí odkaz:
https://doaj.org/article/be369566ee874d27a0bf30ab00df39cd
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-8 (2019)
Abstract Background Medulloblastoma (MB) is the most common malignant brain tumour in children but also rarely occur in adults. Sonic Hedgehog (SHH) driven MB is associated with aberrant activation of the SHH signalling pathway. SMO inhibitors, sonid
Externí odkaz:
https://doaj.org/article/da189fb789214995a1af0d34413f8b08
Autor:
Mathew Lozinski, Nikola A. Bowden, Moira C. Graves, Michael Fay, Bryan W. Day, Brett W. Stringer, Paul A. Tooney
Publikováno v:
Cells, Vol 11, Iss 7, p 1215 (2022)
Glioblastoma is a highly aggressive, invasive and treatment-resistant tumour. The DNA damage response (DDR) provides tumour cells with enhanced ability to activate cell cycle arrest and repair treatment-induced DNA damage. We studied the expression o
Externí odkaz:
https://doaj.org/article/6ff2596000eb4b66b56cea0c64a675e9
Publikováno v:
Bioengineering, Vol 9, Iss 3, p 91 (2022)
Lentiviral vectors are unique and highly efficient genetic tools to incorporate genetic materials into the genome of a variety of cells whilst conserving biosafety. Their rapid acceptance made it necessary to improve existing protocols, including mol
Externí odkaz:
https://doaj.org/article/aa6bd8a64cd347faab33eb5f8b40647b