Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Bryan W Jones"'
Autor:
Alex Woodell, Beth Coughlin, Kannan Kunchithapautham, Sarah Casey, Tucker Williamson, W Drew Ferrell, Carl Atkinson, Bryan W Jones, Bärbel Rohrer
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67894 (2013)
Age-related macular degeneration (AMD), a complex disease involving genetic variants and environmental insults, is among the leading causes of blindness in Western populations. Genetic and histologic evidence implicate the complement system in AMD pa
Externí odkaz:
https://doaj.org/article/7cfd30d76a654c0fbd975821a4f9ff52
Autor:
James R Anderson, Bryan W Jones, Jia-Hui Yang, Marguerite V Shaw, Carl B Watt, Pavel Koshevoy, Joel Spaltenstein, Elizabeth Jurrus, Kannan U V, Ross T Whitaker, David Mastronarde, Tolga Tasdizen, Robert E Marc
Publikováno v:
PLoS Biology, Vol 7, Iss 3, p e1000074 (2009)
Circuitry mapping of metazoan neural systems is difficult because canonical neural regions (regions containing one or more copies of all components) are large, regional borders are uncertain, neuronal diversity is high, and potential network topologi
Externí odkaz:
https://doaj.org/article/110bcb5e76134dd490902ad6459178b1
Autor:
Shayan Farzad, Pragya Kosta, Ege Iseri, Steven T. Walston, Jean-Marie C. Bouteiller, Rebecca L. Pfeiffer, Crystal L. Sigulinsky, Jia-Hui Yang, Jessica C. Garcia, James R. Anderson, Bryan W. Jones, Gianluca Lazzi
Publikováno v:
IEEE Transactions on Neural Systems and Rehabilitation Engineering. 31:2424-2437
Autor:
ALESSANDRA SILVESTRI, ANTONIO GIL-GOMEZ, ELAINE CHIQUETTE, CHRISTIAN DEMITRI, BRYAN W. JONES, ALESSANDRO SANNINO, MARIA RESCIGNO
Publikováno v:
Diabetes. 71
Gelesis' Oral superabsorbent hydrogels (OSH) are crosslinked cellulose-based materials that expand upon hydration in the gastrointestinal tract and are engineered to mimic the mechanical properties of masticated vegetables. One OSH prototype, denoted
Publikováno v:
Microscopy and Microanalysis. 27:3042-3044
Publikováno v:
Trends Endocrinol Metab
Müller cells are glia that play important regulatory roles in retinal metabolism. These roles have been evolutionarily conserved across at least 300 million years. Müller cells have a tightly locked metabolic signature in the healthy retina, which
Autor:
Sieu K. Khuu, Janelle Tong, Nayuta Yoshioka, Barbara Zangerl, Michael Kalloniatis, Jack Phu, Bryan W. Jones, Robert E. Marc, Agnes Yiu Jeung Choi, Lisa Nivison-Smith, Rebecca L. Pfeiffer
Publikováno v:
Am J Ophthalmol
PURPOSE: To develop location specific models of normal, age-related changes in the macular ganglion cell layer (GCL) from optical coherence tomography (OCT). Using these OCT-derived models, we predicted visual field (VF) sensitivity and compared thes
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Primary cilia are conserved organelles found in polarized cells within the eye that regulate cell growth, migration, and differentiation. Although the role of cilia in photoreceptors is well-studied, the formation of cilia in other retinal ce
Autor:
Loyal A. Goff, Jacob S Heng, Jeremy Nathans, Briana L. Winer, Amir Rattner, Hilary J. Vernon, Bryan W. Jones, Genevieve Stein-O’Brien
Publikováno v:
Proceedings of the National Academy of Sciences. 116:9103-9114
The mammalian CNS is capable of tolerating chronic hypoxia, but cell type-specific responses to this stress have not been systematically characterized. In the Norrin KO ( Ndp KO ) mouse, a model of familial exudative vitreoretinopathy (FEVR), develop
Autor:
Bärbel Rohrer, Bryan W. Jones, Elisabeth Obert, Crystal Nicholson, Nathaniel Parsons, Balasubramaniam Annamalai
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose The risk for age-related macular degeneration has been tied to an overactive complement system. Despite combined attempts by academia and industry to develop therapeutics that modulate the complement response, particularly in the late geograp