Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Bryan W, Davies"'
Publikováno v:
mSystems, Vol 9, Iss 10 (2024)
ABSTRACT Class II microcins are antimicrobial peptides that have shown some potential as novel antibiotics. However, to date, only 10 class II microcins have been described, and the discovery of novel microcins has been hampered by their short length
Externí odkaz:
https://doaj.org/article/527c09e5b39a4bf587bf7a36967941ff
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionThe use of microorganisms as drug delivery systems to treat cancer has expanded recently, including FDA approval of certain viruses as oncolytics. Microorganisms have several unique benefits compared to traditional pharmacologic agents in
Externí odkaz:
https://doaj.org/article/85b2be2525e743ab8d32881baae1d2d3
Autor:
Renee M. Fleeman, Bryan W. Davies
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Klebsiella pneumoniae produces a thick capsule layer composed of extracellular polysaccharides protecting the bacterial cells from clearance by innate host immunity during infection. Here we characterize the interactions of a structurally di
Externí odkaz:
https://doaj.org/article/314c35f185994ae3b0b0aba76d5d04d6
Publikováno v:
mSphere, Vol 7, Iss 1 (2022)
ABSTRACT Acinetobacter baumannii is an important hospital-associated pathogen that causes antibiotic resistant infections and reoccurring hospital outbreaks. A. baumannii’s ability to asymptomatically colonize patients is a risk factor for infectio
Externí odkaz:
https://doaj.org/article/09dcd7ab7d4a46bf83ca0e9dcd0105b6
Autor:
Justin R. Randall, Gillian Davidson, Renee M. Fleeman, Santos A. Acosta, Ian M. Riddington, T. Jeffrey Cole, Cory D. DuPai, Bryan W. Davies
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103611- (2022)
Summary: The rapid development and spread of antibiotic resistance necessitate the development of novel strategies for antibiotic discovery. Symbah-1, a synthetic peptide antibiotic, was identified in a high-throughput antibacterial screen of random
Externí odkaz:
https://doaj.org/article/69d8a6c402034da79e413160bbfe08ef
Autor:
Jennifer K Parker, Richard Gu, Gregory A Estrera, Betsy Kirkpatrick, Dusten T Rose, Despoina AI Mavridou, Kristin E Mondy, Bryan W Davies
Publikováno v:
Infection and Drug Resistance. 16:1249-1261
Jennifer K Parker,1 Richard Gu,1 Gregory A Estrera,1 Betsy Kirkpatrick,2 Dusten T Rose,3 Despoina AI Mavridou,1,4 Kristin E Mondy,5 Bryan W Davies1,4 1Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX, USA; 2Austin Pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115ac3a16aaebc96afd91c855630974f
https://doi.org/10.2147/idr.s403448
https://doi.org/10.2147/idr.s403448
Autor:
Heidi A. Butz, Alexandra R. Mey, Ashley L. Ciosek, Alexander A. Crofts, Bryan W. Davies, Shelley M. Payne
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Vibrio cholerae
Externí odkaz:
https://doaj.org/article/77b0d0d64e0f49888614cd8c5a4c1f9d
Publikováno v:
mSphere, Vol 5, Iss 6 (2020)
ABSTRACT Pathogenic strains of Vibrio cholerae require careful regulation of horizontally acquired virulence factors that are largely located on horizontally acquired genomic islands (HAIs). While TsrA, a Vibrionaceae-specific protein, is known to re
Externí odkaz:
https://doaj.org/article/241265e24b73482fa8bf8512cae96ce7
Publikováno v:
mSystems, Vol 5, Iss 4 (2020)
ABSTRACT Research into the evolution and pathogenesis of Vibrio cholerae has benefited greatly from the generation of high-throughput sequencing data to drive molecular analyses. The steady accumulation of these data sets now provides a unique opport
Externí odkaz:
https://doaj.org/article/08b1847653c9482d84f897afde81eab1
Autor:
Sun-Young Kim, Jennifer K. Parker, Monica Gonzalez-Magaldi, Mady S. Telford, Daniel J. Leahy, Bryan W. Davies
Publikováno v:
Applied and Environmental Microbiology. 89
Type I secretion systems for microcin export in Gram-negative bacteria transport small antibacterial proteins from the cytoplasm to the extracellular environment in a single step. In nature, each secretion system is generally paired with a specific s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f4108d8acc1f7576eb29e32017cbb84
https://doi.org/10.1128/aem.00335-23
https://doi.org/10.1128/aem.00335-23