Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Bryan T. Hackfort"'
Autor:
Morgan A. Schake, Ian S. McCue, Evan T. Curtis, Thomas J. Ripperda, Jr., Samuel Harvey, Bryan T. Hackfort, Anna Fitzwater, Yiannis S. Chatzizisis, Forrest M. Kievit, Ryan M. Pedrigi
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106760- (2023)
Summary: Blood flow is a key regulator of atherosclerosis. Disturbed blood flow promotes atherosclerotic plaque development, whereas normal blood flow protects against plaque development. We hypothesized that normal blood flow is also therapeutic, if
Externí odkaz:
https://doaj.org/article/df5f6f2cf0e9416f9819145b79319fb8
Autor:
Prasanta K. Dash, Fadhel A. Alomar, Jesse L. Cox, JoEllyn McMillan, Bryan T. Hackfort, Edward Makarov, Brenda Morsey, Howard S. Fox, Howard E. Gendelman, Santhi Gorantla, Keshore R. Bidasee
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Early-onset heart failure (HF) continues to be a major cause of morbidity and mortality in people living with human immunodeficiency virus type one (HIV-1) infection (PLWH), yet the molecular causes for this remain poorly understood. Herein NOD.Cg-Pr
Externí odkaz:
https://doaj.org/article/4f2a27b9809f46c2b078238674c554a2
Autor:
Sarah L. Schlichte, Elizabeth J. Pekas, Taylor J. Bruett, Elizabeth A. Kosmacek, Bryan T. Hackfort, Jordan M. Rasmussen, Kaushik P. Patel, Song-Young Park, Rebecca E. Oberley-Deegan, Matthew C. Zimmerman
Publikováno v:
Advances in Redox Research, Vol 3, Iss , Pp 100016- (2021)
The pathogenesis of hypertension has been linked to excessive levels of reactive oxygen species (ROS), particularly superoxide (O2•−), in multiple tissues and organ systems. Overexpression of superoxide dismutase (SOD) to scavenge O2•− has be
Externí odkaz:
https://doaj.org/article/0a5e9b3f51f747d9b579aa9d7390f385
Publikováno v:
The FASEB Journal. 36
Publikováno v:
J Mol Cell Cardiol
Under stress, the heart undergoes extensive remodeling resulting in cardiac fibrosis and hypertrophy, ultimately contributing to chronic heart failure (CHF). Alterations in microRNA levels are associated with dysfunctional gene expression profiles in
Autor:
Amy Conaway, Prasanta K. Dash, Fadhel Ahmed Alomar, Howard E. Gendelman, Bryan T. Hackfort, Santhi Gorantla, Larisa Y. Poluektova, Hang Su, Keshore R. Bidasee
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
The molecular cause(s) for early onset heart failure in people living with HIV-1 infection (PLWH) remains poorly defined. Herein, longitudinal echocardiography was used to assess whether NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ mice reconstituted with human
Autor:
Bryan T. Hackfort, Michael C. Wadman, Liang Cao, Dongze Zhang, Robert L. Muelleman, Chaojun Wang, Yu Long Li, Wenfeng Hu, Huiyin Tu
Publikováno v:
Cardiovasc Res
Aims Cardiac sympathetic overactivation is an important trigger of ventricular arrhythmias in patients with chronic heart failure (CHF). Our previous study demonstrated that N-type calcium (Cav2.2) currents in cardiac sympathetic post-ganglionic (CSP
Publikováno v:
The FASEB Journal. 35
Autor:
Hamid R. Shahshahan, Paras Kumar Mishra, David J. Lefer, Tyler N. Kambis, Roopali Yadav, Sumit Kar, Bryan T. Hackfort, Santosh K. Yadav
Publikováno v:
Antioxidants
Volume 8
Issue 12
Volume 8
Issue 12
Obesity increases the risk of developing diabetes and subsequently, diabetic cardiomyopathy (DMCM). Reduced cardioprotective antioxidant hydrogen sulfide (H2S) and increased inflammatory cell death via pyroptosis contribute to adverse cardiac remodel
Autor:
Rebecca E. Oberley-Deegan, Elizabeth J. Pekas, Matthew C. Zimmerman, Sarah L. Schlichte, Elizabeth A. Kosmacek, Song-Young Park, Kaushik P. Patel, Bryan T. Hackfort, Taylor J. Bruett, Jordan M. Rasmussen
Publikováno v:
Advances in Redox Research, Vol 3, Iss, Pp 100016-(2021)
The pathogenesis of hypertension has been linked to excessive levels of reactive oxygen species (ROS), particularly superoxide (O2•−), in multiple tissues and organ systems. Overexpression of superoxide dismutase (SOD) to scavenge O2•− has be