Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Bryan Simard"'
Autor:
Frank C. J. M. van Veggel, Boguslaw Tomanek, Abedelnasser Abulrob, Gleb G. Mironov, Bryan Simard
Publikováno v:
Journal of Peptide Science. 22:415-420
Optical imaging offers high sensitivity and portability at low cost. The design of 'smart' or 'activatable' probes can decrease the background noise and increase the specificity of the signal. By conjugating a fluorescent dye and a compatible quenche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1602fe47ba8d6a4e00aff9bea3ce398e
https://doi.org/10.1002/psc.2884
https://doi.org/10.1002/psc.2884
Autor:
Bryan, Simard, Gleb G, Mironov, Boguslaw, Tomanek, Frank C J M, van Veggel, Abedelnasser, Abulrob
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 22(6)
Optical imaging offers high sensitivity and portability at low cost. The design of 'smart' or 'activatable' probes can decrease the background noise and increase the specificity of the signal. By conjugating a fluorescent dye and a compatible quenche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e7dc44143da1fd77c670e863180da4c
https://pubmed.ncbi.nlm.nih.gov/27282138
https://pubmed.ncbi.nlm.nih.gov/27282138
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 80:1203-1207
The morbidity and mortality associated with type 1 diabetes are essentially related to the micro- and macro-vascular complications that develop over time and lead to several diabetic complications, including hypertension, atherosclerosis, and retinop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8cac8d201ed1e354994aeda3a9d34d
https://doi.org/10.1139/y02-153
https://doi.org/10.1139/y02-153
Publikováno v:
Cytokine. 61(1)
Neovastat® is a standardized extract of marine cartilage, an avascular tissue, which contains many biologically active molecules and has multiple antiangiogenic properties. In addition to VEGFR2 and MMPs inhibition, shark cartilage extract (SCE) has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f6e6b29fb727e205f0b013991fd7d3
https://pubmed.ncbi.nlm.nih.gov/23063000
https://pubmed.ncbi.nlm.nih.gov/23063000
Autor:
Gilles Pernod, Peggy Jourdes, Violetta Dimitriadou, A Bouamrani, François Berger, Bryan Simard
Publikováno v:
Microvascular research. 82(1)
Both the antiangiogenic and antitumoral activity of shark cartilage extracts (SCE) have been demonstrated in animal models and clinical trials. Studies reported that SCE induces the expression of tissue plasminogen activator gene (PLAT) in endothelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921d502768c8e6ac474bd1993912ede4
https://pubmed.ncbi.nlm.nih.gov/21406197
https://pubmed.ncbi.nlm.nih.gov/21406197
Autor:
Gilles Pernod, Benoît Polack, Richard J. Fish, N. Bolle, Egbert K. O. Kruithof, Bryan Simard, F. Solly
Publikováno v:
Cancer Gene Therapy
Cancer Gene Therapy, Nature Publishing Group, 2008, 15 (10), pp.685-92. ⟨10.1038/cgt.2008.36⟩
Cancer Gene Therapy, Vol. 15, No 10 (2008) pp. 685-692
Cancer Gene Therapy, Nature Publishing Group, 2008, 15 (10), pp.685-92. ⟨10.1038/cgt.2008.36⟩
Cancer Gene Therapy, Vol. 15, No 10 (2008) pp. 685-692
International audience; Tissue-type plasminogen activator (tPA) plays a major role in the fibrinolytic system. According to several reports, tPA may also have antiangiogenic properties, especially in combination with a free sulfhydryl donor (FSD). In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91496ced60fe0ba5fababbb8156fcb69
https://pubmed.ncbi.nlm.nih.gov/18535615
https://pubmed.ncbi.nlm.nih.gov/18535615
Autor:
Richard, Béliveau, Denis, Gingras, Erwin A, Kruger, Sylvie, Lamy, Pierre, Sirois, Bryan, Simard, Martin G, Sirois, Leone, Tranqui, Fabienne, Baffert, Edith, Beaulieu, Violetta, Dimitriadou, Marie-Claude, Pépin, Frank, Courjal, Isabelle, Ricard, Patrick, Poyet, Pierre, Falardeau, William D, Figg, Eric, Dupont
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 8(4)
Vascular endothelial growth factor (VEGF) is a potent regulator of angiogenesis, which exerts direct effects on vascular endothelial cells, including endothelial cell proliferation and survival, tubulogenesis, and vascular permeability. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::754876cc919a3fabe7519bb803b0b485
https://pubmed.ncbi.nlm.nih.gov/11948139
https://pubmed.ncbi.nlm.nih.gov/11948139
Autor:
Chris M. Farnet, Pierre Falardeau, Maxime Ranger, James B. McAlpine, François Berger, Henriette Gourdeau, Francis Beaudry, Bryan Simard
Publikováno v:
Cancer Chemotherapy and Pharmacology
Cancer Chemotherapy and Pharmacology, Springer Verlag, 2008, 61 (6), pp.911-21. ⟨10.1007/s00280-007-0544-2⟩
Cancer Chemotherapy and Pharmacology, Springer Verlag, 2008, 61 (6), pp.911-21. ⟨10.1007/s00280-007-0544-2⟩
International audience; PURPOSE: ECO-4601 is a structurally novel farnesylated dibenzodiazepinone discovered through DECIPHER technology, Thallion's proprietary drug discovery platform. The compound was shown to have a broad cytotoxic activity in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6f7e5b901f9f0a536db80b775e7273
https://doi.org/10.1007/s00280-008-0848-x
https://doi.org/10.1007/s00280-008-0848-x