Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Bryan R. Conway"'
Autor:
Anna Kolb, Peter J. Gallacher, Jacqueline Campbell, Martin O’Neill, James R. Smith, Samira Bell, Bryan R. Conway, Wendy Metcalfe, Nicola Joss, Vishal Dey, Annette Alfonzo, Michael Kelly, Shahzad Shah, Emily McQuarrie, Colin Geddes, Jamie Traynor, Robert W. Hunter
Publikováno v:
Kidney International Reports, Vol 6, Iss 2, Pp 449-459 (2021)
Introduction: We aimed to determine the mortality rate, cause of death, and rate of end-stage kidney disease (ESKD) in adults with nephrotic syndrome (NS). Methods: We conducted a national registry–based study, including all 522 adults who had a ki
Externí odkaz:
https://doaj.org/article/dcbdaaafbd474f579517b63c725d4726
Autor:
Katie L. Connor, Oliver Teenan, Carolynn Cairns, Victoria Banwell, Rachel A.B. Thomas, Julie Rodor, Sarah Finnie, Riinu Pius, Gillian M. Tannahill, Vishal Sahni, Caroline O.S. Savage, Jeremy Hughes, Ewen M. Harrison, Robert B. Henderson, Lorna P. Marson, Bryan R. Conway, Stephen J. Wigmore, Laura Denby
Publikováno v:
JCI Insight, Vol 5, Iss 24 (2020)
Small noncoding RNAs, miRNAs (miRNAs), are emerging as important modulators in the pathogenesis of kidney disease, with potential as biomarkers of kidney disease onset, progression, or therapeutic efficacy. Bulk tissue small RNA-sequencing (sRNA-Seq)
Externí odkaz:
https://doaj.org/article/0e57397672654b13af1fc22e1d4a45d8
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 12, Pp 1419-1433 (2016)
The rat has classically been the species of choice for pharmacological studies and disease modeling, providing a source of high-quality physiological data on cardiovascular and renal pathophysiology over many decades. Recent developments in genome en
Externí odkaz:
https://doaj.org/article/5e2b82ec40dd485d849c393926b5e345
Autor:
Rachel M B, Bell, Bryan R, Conway
Publikováno v:
International review of cell and molecular biology. 367
Macrophages are a key component of the renal mononuclear phagocyte system, playing a major role in defense against infection, renal injury and repair. Yolk sac macrophage precursors seed the early embryonic kidney and are important for renal developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::67818e150605ac473ff11bc097e3746d
https://pubmed.ncbi.nlm.nih.gov/35461656
https://pubmed.ncbi.nlm.nih.gov/35461656
Autor:
Oliver Teenan, Vishal Sahni, Robert B. Henderson, Bryan R. Conway, Carmel M. Moran, Jeremy Hughes, Laura Denby
Publikováno v:
Teenan, O, Sahni, V, Henderson, R B, Conway, B R, Moran, C M, Hughes, J & Denby, L 2022, ' Sonoporation of human renal proximal tubular epithelial cells in vitro to enhance the liberation of intracellular miRNA biomarkers. ', Ultrasound in Medicine and Biology (UMB) . https://doi.org/10.1016/j.ultrasmedbio.2022.01.019
Ultrasound has previously been demonstrated to non-invasively cause tissue disruption. Small animal studies have demonstrated that this effect can be enhanced by contrast microbubbles and has the potential to be clinically beneficial in techniques su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3002672e1be35f6f764e3f74ebf3d9
https://www.pure.ed.ac.uk/ws/files/251511161/Teenan_et_al_2020_v13_revised_January_2022.docx
https://www.pure.ed.ac.uk/ws/files/251511161/Teenan_et_al_2020_v13_revised_January_2022.docx
Autor:
Anna Kolb, Jacqueline Campbell, Bryan R. Conway, Emily P. McQuarrie, Samira Bell, Jamie P. Traynor, Michael Kelly, Wendy Metcalfe, Annette V.M. Alfonzo, Nicola Joss, James R Smith, Robert W. Hunter, Shahzad Shah, Colin C. Geddes, Vishal Dey, Martin O’Neill, Peter J. Gallacher
Publikováno v:
Kidney International Reports
Kolb, A, Gallacher, P J, Campbell, J, O’neill, M, Smith, J R, Bell, S, Conway, B R, Metcalfe, W, Joss, N, Dey, V, Alfonzo, A, Kelly, M, Shah, S, Mcquarrie, E, Geddes, C, Traynor, J & Hunter, R W 2021, ' A National Registry Study of Patient and Renal Survival in Adult Nephrotic Syndrome ', Kidney International Reports, vol. 6, no. 2, pp. 449-459 . https://doi.org/10.1016/j.ekir.2020.10.033
Kidney International Reports, Vol 6, Iss 2, Pp 449-459 (2021)
Kolb, A, Gallacher, P J, Campbell, J, O’neill, M, Smith, J R, Bell, S, Conway, B R, Metcalfe, W, Joss, N, Dey, V, Alfonzo, A, Kelly, M, Shah, S, Mcquarrie, E, Geddes, C, Traynor, J & Hunter, R W 2021, ' A National Registry Study of Patient and Renal Survival in Adult Nephrotic Syndrome ', Kidney International Reports, vol. 6, no. 2, pp. 449-459 . https://doi.org/10.1016/j.ekir.2020.10.033
Kidney International Reports, Vol 6, Iss 2, Pp 449-459 (2021)
Introduction We aimed to determine the mortality rate, cause of death, and rate of end-stage kidney disease (ESKD) in adults with nephrotic syndrome (NS). Methods We conducted a national registry–based study, including all 522 adults who had a kidn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3644d82444a58a18a35150718451968e
http://europepmc.org/articles/PMC7879209
http://europepmc.org/articles/PMC7879209
Autor:
Dawn E W Livingstone, John J. Mullins, Kevin Stewart, John Wiseman, James W. Dear, Carmel M. Moran, Bryan R. Conway, Patrick W. F. Hadoke, Laura Denby, Robert I. Menzies, Matthew A. Bailey, Natalie K. Jones, David J. Webb, Alicja Czopek, Adrian Thomson, Carolynn Cairns, Neeraj Dhaun
Publikováno v:
Jones, N, Stewart, K, Czopek, A, Menzies, R, Thomson, A W, Moran, C, Cairns, C, Conway, B, Denby, L, Livingstone, D, Wiseman, J, Hadoke, P, Webb, D, Dhaun, N, Dear, J, Mullins, J & Bailey, M 2020, ' Endothelin-1 mediates the systemic and renal hemodynamic effects of GPR81 activation ', Hypertension . https://doi.org/10.1161/HYPERTENSIONAHA.119.14308
Hypertension (Dallas, Tex. : 1979)
Hypertension (Dallas, Tex. : 1979)
Supplemental Digital Content is available in the text.
GPR81 (G-protein-coupled receptor 81) is highly expressed in adipocytes, and activation by the endogenous ligand lactate inhibits lipolysis. GPR81 is also expressed in the heart, liver, and
GPR81 (G-protein-coupled receptor 81) is highly expressed in adipocytes, and activation by the endogenous ligand lactate inhibits lipolysis. GPR81 is also expressed in the heart, liver, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db93e9f8bfa30f8527af2997cc8ba983
https://doi.org/10.1161/hypertensionaha.119.14308
https://doi.org/10.1161/hypertensionaha.119.14308
Autor:
Rachel M.B. Bell, Bryan R. Conway
Publikováno v:
International Review of Cell and Molecular Biology ISBN: 9780323907415
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9708caf49d397e4521f4ce52386d693b
https://doi.org/10.1016/bs.ircmb.2022.01.005
https://doi.org/10.1016/bs.ircmb.2022.01.005
Autor:
Albert Tenesa, Cathie Sudlow, Rainer Malik, Sophie Thrippleton, Amy C Ferguson, Bryan R. Conway, Kristiina Rannikmäe, Konrad Rawlik, Malcolm R. Macleod, Ed Whittaker, David E. Henshall
Based on previous case reports and disease-based cohorts, a minority of patients with cerebral small vessel disease (cSVD) have a monogenic cause, with many also manifesting extra-cerebral phenotypes. We investigated the frequency, penetrance, and ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14587d3b7594ff3e3227e629127d4830
https://doi.org/10.1101/2021.11.17.21266447
https://doi.org/10.1101/2021.11.17.21266447
Autor:
Cuiyan Xin, Bryan R. Conway, Sarah Finnie, Joseph V. Bonventre, Laura Denby, Cyril Carvalho, Julia Wilflingseder, Neil Henderson, Jeremy Hughes, Eoin O'Sullivan, Angela Oliveira Pisco, Michaela Willi, Katie J. Mylonas, David A. Ferenbach
Chronic kidney disease (CKD) and ageing inhibit tissue regeneration and increase risks of organ fibrosis and cardiovascular disease. Increased numbers of leukocytes are present in the circulation and within the kidney of ageing individuals and patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4615b28a91782b677f72a3c9921f9261
https://doi.org/10.21203/rs.3.rs-793155/v1
https://doi.org/10.21203/rs.3.rs-793155/v1