Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Bryan R Haugen"'
Autor:
Nikita Pozdeyev, Adam Berlinberg, Qiong Zhou, Kelsey Wuensch, Hiroyuki Shibata, William M Wood, Bryan R Haugen
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134901 (2015)
NF-κB signaling plays an important role in tumor cell proliferation, cell survival, angiogenesis, invasion, metastasis and drug/radiation resistance. Combination therapy involving NF-κB pathway inhibition is an attractive strategy for the treatment
Externí odkaz:
https://doaj.org/article/129280423c93467185b7ddc62f3d03e9
Autor:
Min Ji Jeon, Bryan R. Haugen
Publikováno v:
Endocrinology and Metabolism, Vol 37, Iss 6, Pp 830-838 (2022)
The overall prognosis of thyroid cancer is excellent, but some patients have grossly invasive disease and distant metastases with limited responses to systemic therapies. Thus, relevant preclinical models are needed to investigate thyroid cancer biol
Externí odkaz:
https://doaj.org/article/734dbe8cbe75451b98f531fecf8ceb4c
Autor:
Martin Barrio, Christopher D. Raeburn, Robert McIntyre, Maria Albuja-Cruz, Bryan R. Haugen, Nikita Pozdeyev
Publikováno v:
Thyroid. 33:547-555
Autor:
Simion Chiosea, Steven P Hodak, Linwah Yip, Devaprabu Abraham, Chelsey Baldwin, Zubair Baloch, Seza A Gulec, Zeina C Hannoush, Bryan R Haugen, Lija Joseph, Atil Y Kargi, Elham Khanafshar, Masha J Livhits, Bryan McIver, Kepal Patel, Snehal G Patel, Gregory W Randolph, Ashok R Shaha, Jyotirmay Sharma, Nikolaos Stathatos, Annemieke van Zante, Sally E Carty, Yuri E Nikiforov, Marina N Nikiforova
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism.
Context Comprehensive genomic analysis of thyroid nodules for multiple classes of molecular alterations detected in a large series of fine needle aspiration (FNA) samples has not been reported. Objective To determine the prevalence of clinically rele
Autor:
Nikita Pozdeyev, Manjiri Dighe, Martin Barrio, Christopher Raeburn, Harry Smith, Matthew Fisher, Sameer Chavan, Nicholas Rafaels, Jonathan A. Shortt, Meng Lin, Michael G. Leu, Toshimasa Clark, Carrie Marshall, Bryan R. Haugen, Devika Subramanian, Regeneron Genetics Center, Kristy Crooks, Christopher Gignoux, Trevor Cohen
Evaluating thyroid nodules to rule out malignancy is a very common clinical task. Image-based clinical and machine learning risk stratification schemas rely on the presence of thyroid nodule high-risk sonographic features. However, this approach is l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c854fe7553844c314bc0efc1182c4cc
https://doi.org/10.1101/2023.04.11.23288041
https://doi.org/10.1101/2023.04.11.23288041
Autor:
Jena D. French, Bryan R. Haugen, Sharon B. Sams, Robert C. McIntyre, Christopher D. Raeburn, Valerica Mateescu, Hilary S. Serracino, Jill J. Severson
Supplementary Figure 2. PMA/ionomycin and anti-CD3/anti-CD28 induce up-regulation of PD-1 and Tim-3. Non-adherent cells from TILN were left untreated (US) or stimulated with anti-CD3/anti-CD28 or PMA/ionomycin (P/I) for 6 hours to assess cytokine exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc0e2855daff7e386bca9f8a4ddaa6a
https://doi.org/10.1158/2326-6066.22538240
https://doi.org/10.1158/2326-6066.22538240
Autor:
Jena D. French, Bryan R. Haugen, Sharon B. Sams, Robert C. McIntyre, Christopher D. Raeburn, Valerica Mateescu, Hilary S. Serracino, Jill J. Severson
Regional metastatic differentiated thyroid cancer (mDTC) provides a unique model in which to study the tumor–immune interface. These lymph node metastases persist for years, generally without progression to distant metastases. Although the immune s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5df283ed6e78183e02110a635ea51bc
https://doi.org/10.1158/2326-6066.c.6548720.v1
https://doi.org/10.1158/2326-6066.c.6548720.v1
Autor:
Jena D. French, Bryan R. Haugen, Sharon B. Sams, Robert C. McIntyre, Christopher D. Raeburn, Valerica Mateescu, Hilary S. Serracino, Jill J. Severson
Supplementary Figure 3. Stimulated Cytokine Production in Peripheral Blood T Cells. Lymphocytes from peripheral blood (A) or normal LN (B) were stimulated with PMA/ionomycin and analyzed by flow cytometry for cytokine expression. CD8+ or CD4+ T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5422fcfeaff823dba8c8d304ba12b6ed
https://doi.org/10.1158/2326-6066.22538237.v1
https://doi.org/10.1158/2326-6066.22538237.v1
Autor:
Bryan R. Haugen, James A. Fagin, Jeffrey A. Knauf, Iñigo Landa, Daniel V. LaBarbera, Philip Reigan, Maria B. Albuja-Cruz, Christopher Raeburn, Umarani Pugazhenthi, Vibha Sharma, Sharon B. Sams, Qiong Zhou, Christopher Korch, Laura A. Pike, Nikita Pozdeyev, Rebecca E. Schweppe
Electropherograms of the CUTC5, CUTC48, CUTC60 and CUTC61 cell line, PDX, and patient samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217c351ac513de8c219d6acdec51feea
https://doi.org/10.1158/1541-7786.22512805.v1
https://doi.org/10.1158/1541-7786.22512805.v1
Autor:
Jena D. French, Bryan R. Haugen, Sharon B. Sams, Robert C. McIntyre, Christopher D. Raeburn, Valerica Mateescu, Hilary S. Serracino, Jill J. Severson
Supplementary Figure 1. PD-1+ T cells in TILN are largely CD45RO+RA-CCR7- effector memory cells (TEM). T cells from PB, normal lymph node, and TILN sections from patients 11 and 12 were analyzed by flow cytometry. CD8+ and CD4+ CD3+ T cells were gate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f962d2b31dbd46508e0d57d39275871
https://doi.org/10.1158/2326-6066.22538243
https://doi.org/10.1158/2326-6066.22538243