Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bryan Pursell"'
Autor:
Hira Lal Goel, Bryan Pursell, Leonard D. Shultz, Dale L. Greiner, Rolf A. Brekken, Craig W. Vander Kooi, Arthur M. Mercurio
Publikováno v:
Cell Reports, Vol 14, Iss 9, Pp 2193-2208 (2016)
Autocrine VEGF signaling is critical for sustaining prostate and other cancer stem cells (CSCs), and it is a potential therapeutic target, but we observed that CSCs isolated from prostate tumors are resistant to anti-VEGF (bevacizumab) and anti-VEGFR
Externí odkaz:
https://doaj.org/article/8c17537e827f446195f5c1b49e43bb2d
Autor:
Hira Lal Goel, Tatiana Gritsko, Bryan Pursell, Cheng Chang, Leonard D. Shultz, Dale L. Greiner, Jens Henrik Norum, Rune Toftgard, Leslie M. Shaw, Arthur M. Mercurio
Publikováno v:
Cell Reports, Vol 7, Iss 3, Pp 747-761 (2014)
Although the α6β1 integrin has been implicated in the function of breast and other cancer stem cells (CSCs), little is known about its regulation and relationship to mechanisms involved in the genesis of CSCs. We report that a CD44high/CD24low popu
Externí odkaz:
https://doaj.org/article/4e1a162adbeb445b9041895eb6512251
Autor:
Arthur M. Mercurio, Stephen R. Plymate, Roger J. Davis, Robert L. Vessella, Peter S. Nelson, Ilsa M. Coleman, Pradip Roy-Burman, Helty Adisetiyo, Chung-Cheng Hsieh, Hualin Simon Xi, Stephen Lyle, Irwin Leav, Bryan Pursell, Cheng Chang, Hira Lal Goel
PDF file - 819K, List of primer sequences for semi-quantitative and quantitative PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf73393db3013b6384478cc00eef3b5c
https://doi.org/10.1158/2159-8290.22528323
https://doi.org/10.1158/2159-8290.22528323
Autor:
Arthur M. Mercurio, Stephen R. Plymate, Roger J. Davis, Robert L. Vessella, Peter S. Nelson, Ilsa M. Coleman, Pradip Roy-Burman, Helty Adisetiyo, Chung-Cheng Hsieh, Hualin Simon Xi, Stephen Lyle, Irwin Leav, Bryan Pursell, Cheng Chang, Hira Lal Goel
PDF file - 504K, Response of xenografts of human prostate cancer specimens to IGF-1R inhibition as a function of NRP2 expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295edcca33a65a6ce1108ff9fdef3db9
https://doi.org/10.1158/2159-8290.22528326.v1
https://doi.org/10.1158/2159-8290.22528326.v1
Autor:
Arthur M. Mercurio, Stephen R. Plymate, Roger J. Davis, Robert L. Vessella, Peter S. Nelson, Ilsa M. Coleman, Pradip Roy-Burman, Helty Adisetiyo, Chung-Cheng Hsieh, Hualin Simon Xi, Stephen Lyle, Irwin Leav, Bryan Pursell, Cheng Chang, Hira Lal Goel
PDF file - 454K, Role of JNK/c-Jun in regulating NRP2 expression in prostate carcinoma cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3efccae0f6307b050a11fd5c4d33e409
https://doi.org/10.1158/2159-8290.22528335
https://doi.org/10.1158/2159-8290.22528335
Autor:
Arthur M. Mercurio, Stephen R. Plymate, Roger J. Davis, Robert L. Vessella, Peter S. Nelson, Ilsa M. Coleman, Pradip Roy-Burman, Helty Adisetiyo, Chung-Cheng Hsieh, Hualin Simon Xi, Stephen Lyle, Irwin Leav, Bryan Pursell, Cheng Chang, Hira Lal Goel
PDF file - 1.8MB, Evaluation of insulin signaling in prostate tumors and cell lines as a function of NRP2 expression and role of VEGF in regulation of Bmi-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234d2f155ca4325ac0e5289d5af835d8
https://doi.org/10.1158/2159-8290.22528329.v1
https://doi.org/10.1158/2159-8290.22528329.v1
Autor:
Arthur M. Mercurio, Stephen R. Plymate, Roger J. Davis, Robert L. Vessella, Peter S. Nelson, Ilsa M. Coleman, Pradip Roy-Burman, Helty Adisetiyo, Chung-Cheng Hsieh, Hualin Simon Xi, Stephen Lyle, Irwin Leav, Bryan Pursell, Cheng Chang, Hira Lal Goel
We show that the VEGF receptor neuropilin-2 (NRP2) is associated with high-grade, PTEN-null prostate cancer and that its expression in tumor cells is induced by PTEN loss as a consequence of c-Jun activation. VEGF/NRP2 signaling represses insulin-lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0392679cb4149d201f91278b922d2110
https://doi.org/10.1158/2159-8290.c.6545694
https://doi.org/10.1158/2159-8290.c.6545694
Autor:
Arthur M. Mercurio, Stephen R. Plymate, Roger J. Davis, Robert L. Vessella, Peter S. Nelson, Ilsa M. Coleman, Pradip Roy-Burman, Helty Adisetiyo, Chung-Cheng Hsieh, Hualin Simon Xi, Stephen Lyle, Irwin Leav, Bryan Pursell, Cheng Chang, Hira Lal Goel
PDF file - 2.5MB, Correlation of NRP2 expression in prostate cancer with clinical parameters and expression of VEGFRs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3535b23d5b88d471b4e5cab525db18d3
https://doi.org/10.1158/2159-8290.22528341.v1
https://doi.org/10.1158/2159-8290.22528341.v1
Autor:
Arthur M. Mercurio, Stephen R. Plymate, Roger J. Davis, Robert L. Vessella, Peter S. Nelson, Ilsa M. Coleman, Pradip Roy-Burman, Helty Adisetiyo, Chung-Cheng Hsieh, Hualin Simon Xi, Stephen Lyle, Irwin Leav, Bryan Pursell, Cheng Chang, Hira Lal Goel
PDF file - 536K, Invasive behavior of cell lines used and assessment of NRP2 expression in prostate glands and cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb96b4c77136ef53a994aaf9e4088ac
https://doi.org/10.1158/2159-8290.22528344.v1
https://doi.org/10.1158/2159-8290.22528344.v1
Autor:
Arthur M. Mercurio, Stephen R. Plymate, Roger J. Davis, Robert L. Vessella, Peter S. Nelson, Ilsa M. Coleman, Pradip Roy-Burman, Helty Adisetiyo, Chung-Cheng Hsieh, Hualin Simon Xi, Stephen Lyle, Irwin Leav, Bryan Pursell, Cheng Chang, Hira Lal Goel
PDF file - 484K, Evaluation of the contribution of FOXO1 to NRP2 expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2803b98159171c356ab2e8303473979b
https://doi.org/10.1158/2159-8290.22528332.v1
https://doi.org/10.1158/2159-8290.22528332.v1