Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Bryan P Roxas"'
Autor:
Michele Chu, Michael J G Mallozzi, Bryan P Roxas, Lisa Bertolo, Mario A Monteiro, Al Agellon, V K Viswanathan, Gayatri Vedantam
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005946 (2016)
Clostridium difficile is a diarrheagenic pathogen associated with significant mortality and morbidity. While its glucosylating toxins are primary virulence determinants, there is increasing appreciation of important roles for non-toxin factors in C.
Externí odkaz:
https://doaj.org/article/12e18a6f7b9d4631b886b59e873922ff
Publikováno v:
Analytical Chemistry. 80:396-406
We determined the global protein turnover profiles for Mycobacterium smegmatis under acid shock and iron starvation conditions using a simple (15)N isotope doping technique and a complete medium replacement method for chasing. We used a high-resoluti
Autor:
Janet Chin, Yogen Saunthararajah, Pasit Phiasivongsa, Donald Lavelle, Roselle Will, Mahipal Singh, Kestis Vaitkus, Chunlin Tang, Maria Hankewych, Joseph DeSimone, Sanjeev Redkar, Bryan P. Roxas
Publikováno v:
American Journal of Hematology. 82:981-985
The silencing of tumor suppressor genes associated with increased DNA methylation of the promoter regions is a frequent observation in many forms of cancer. Reactivation of these genes using pharmacological inhibitors of DNA methyltransferase such as
Publikováno v:
Hypertension. 43:282-285
Aminopeptidase N (APN) is an abundant metallohydrolase in the brush border of kidney proximal tubule cells that degrades angiotensin III (Ang III) to angiotensin IV (Ang IV) and, along with dipeptidylaminopeptidase, degrades Ang IV. We examined the i
Autor:
Bryan P. Roxas, Qingbo Li
Publikováno v:
BMC Bioinformatics, Vol 10, Iss 1, p 43 (2009)
BMC Bioinformatics
BMC Bioinformatics
Background Many studies have provided algorithms or methods to assess a statistical significance in quantitative proteomics when multiple replicates for a protein sample and a LC/MS analysis are available. But, confidence is still lacking in using da
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 41(4)
Serum and glucocorticoid-induced kinase 1 (SGK1) activates the epithelial sodium channel (eNaC) in tubules. We examined renal SGK1 abundance in salt-adaptation and in salt-sensitive hypertension. Sprague-Dawley and Dahl salt-sensitive rats were place
Publikováno v:
Biochemical and biophysical research communications. 296(3)
Aquaporin-2 (AQP-2) is a vasopressin-regulated water channel in the kidney collecting duct. AQP-2 transcript has been identified by transcriptional profiling of rat kidneys as being regulated by dietary salt. We compared renal AQP-2 transcript expres
Publikováno v:
American Journal of Hypertension. 16:A163-A164
Publikováno v:
American Journal of Hypertension. 16:A22-A23
Autor:
Qingbo Li, Bryan P. Roxas
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 9, Iss 1, p 187 (2008)
BMC Bioinformatics, Vol 9, Iss 1, p 187 (2008)
Background Although fold change is a commonly used criterion in quantitative proteomics for differentiating regulated proteins, it does not provide an estimation of false positive and false negative rates that is often desirable in a large-scale quan