Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Bryan P Hurley"'
Autor:
Michael A Pazos, Bernard B Lanter, Lael M Yonker, Alex D Eaton, Waheed Pirzai, Karsten Gronert, Joseph V Bonventre, Bryan P Hurley
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006548 (2017)
Excessive neutrophil infiltration of the lungs is a common contributor to immune-related pathology in many pulmonary disease states. In response to pathogenic infection, airway epithelial cells produce hepoxilin A3 (HXA3), initiating neutrophil trans
Externí odkaz:
https://doaj.org/article/af2c8f88c5164c6d8be84c7240e433b0
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160937 (2016)
Gut commensal bacteria contribute to the pathogenesis of inflammatory bowel disease, in part by activating the inflammasome and inducing secretion of interleukin-1ß (IL-1ß). Although much has been learned about inflammasome activation by bacterial
Externí odkaz:
https://doaj.org/article/d8bc426ce8d841cdaf4ddc361b345123
Autor:
Alex Hopke, Tian Lin, Allison K. Scherer, Ashley E. Shay, Kyle D. Timmer, Brittany Wilson-Mifsud, Michael K. Mansour, Charles N. Serhan, Daniel Irimia, Bryan P. Hurley
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105226- (2022)
Summary: Neutrophil swarming is an emergent host defense mechanism triggered by targets larger than a single neutrophil’s capacity to phagocytose. Swarming synergizes neutrophil functions, including chemotaxis, phagocytosis, and reactive oxygen spe
Externí odkaz:
https://doaj.org/article/9702e75d772246ab84e3c19a0369c655
Autor:
Bethany L. Bartley, Kelly J. Gardner, Stefano Spina, Bryan P. Hurley, David Campeau, Lorenzo Berra, Lael M. Yonker, Ryan W. Carroll
Publikováno v:
Case Reports in Pediatrics, Vol 2020 (2020)
Background. Individuals with cystic fibrosis (CF) have persistent lung infections, necessitating the frequent use of antibiotics for pulmonary exacerbations. Some respiratory pathogens have intrinsic resistance to the currently available antibiotics,
Externí odkaz:
https://doaj.org/article/a079b612cbb042cb9393dda2ff412926
Autor:
Lael M. Yonker, Hongmei Mou, Kengyeh K. Chu, Michael A. Pazos, Huimin Leung, Dongyao Cui, Jinhyeob Ryu, Rhianna M. Hibbler, Alexander D. Eaton, Tim N. Ford, J. R. Falck, T. Bernard Kinane, Guillermo J. Tearney, Jayaraj Rajagopal, Bryan P. Hurley
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Neutrophil breach of the mucosal surface is a common pathological consequence of infection. We present an advanced co-culture model to explore neutrophil transepithelial migration utilizing airway mucosal barriers differentiated from primary
Externí odkaz:
https://doaj.org/article/27f6d6cde653441b8cceb7c78149692a
Autor:
Tina L. Samuels, Ke Yan, Nishma Patel, Kate Plehhova, Cathal Coyle, Bryan P. Hurley, Nikki Johnston
Publikováno v:
The Laryngoscope. 132:2327-2334
Gastroesophageal reflux disease (GERD) and laryngopharyngeal reflux (LPR) are chronic conditions caused by backflow of gastric and duodenal contents into the esophagus and proximal aerodigestive tract, respectively. Mucosal barrier dysfunction result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52035d88551065d329097009496e6c6
https://doi.org/10.1002/lary.30087
https://doi.org/10.1002/lary.30087
Autor:
Yihan Zhang, Katharine Elliot Black, Thien-Khoi N Phung, Sujatha Rajeev Thundivalappil, Tian Lin, Wei Wang, Jie Xu, Cheng Zhang, Lida P Hariri, Allen Lapey, Hu Li, Paul Hubert Lerou, Xingbin Ai, Jianwen Que, Jin-Ah Park, Bryan P Hurley, Hongmei Mou
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f8929ebd4bbbe89396db02be01af888
https://doi.org/10.1165/rcmb.2022-0299oc
https://doi.org/10.1165/rcmb.2022-0299oc
Autor:
Yihan Zhang, Tian Lin, Hui Min Leung, Cheng Zhang, Brittany Wilson-Mifsud, Michael B. Feldman, Anne Puel, Fanny Lanternier, Louis-Jean Couderc, Francois Danion, Emilie Catherinot, Hélène Salvator, Colas Tcherkian, Claire Givel, Jie Xu, Guillermo J. Tearney, Jatin M. Vyas, Hu Li, Bryan P. Hurley, Hongmei Mou
Publikováno v:
Journal of Allergy and Clinical Immunology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42550484286dabb59fd37b622b2c36bd
https://doi.org/10.1016/j.jaci.2022.12.821
https://doi.org/10.1016/j.jaci.2022.12.821
Autor:
Hui Min Leung, Lael M. Yonker, Guillermo J. Tearney, Anika L. Marand, Grace Park, Lauren B. Guthrie, Hanna T. Pinsky, Daniel Irimia, Sinan K. Muldur, Alex Hopke, Bryan P. Hurley, Denis De la Flor
Publikováno v:
J Cyst Fibros
BACKGROUND: Excessive neutrophil inflammation is the hallmark of cystic fibrosis (CF) airway disease. Novel technologies for characterizing neutrophil dysfunction may provide insight into the nature of these abnormalities, revealing a greater mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b47ea11421df442efdd66f4adafcb4
https://doi.org/10.1016/j.jcf.2021.01.012
https://doi.org/10.1016/j.jcf.2021.01.012
Publikováno v:
Clinical Pharmacology & Therapeutics. 110:69-81
Inflammation of the airway involves the recruitment of highly active immune cells to combat and clear microbes and toxic factors; however, this inflammatory response can result in unintended damage to lung tissue. Tissue damage resulting from inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e744e1ff9bdc7f567b247f04a72b68f5
https://doi.org/10.1002/cpt.2165
https://doi.org/10.1002/cpt.2165