Výsledky vyhledávání - "Bryan Mark O'hara"

Novel Class of Thiourea Compounds That Inhibit Herpes Simplex Virus Type 1 DNA Cleavage and Encapsidation: Resistance Maps to the UL6 Gene

Autor: S V Johann, Morin John Edward, Bloom Jonathan David, Larocque James Paul, Boris Feld, Bryan Mark O'hara, Jeanette Fairhurst, Steven K. Vernon, Marja van Zeijl, Thomas R. Jones

Publikováno v: Journal of Virology. 74:9054-9061

The herpesvirus family has many members that are human pathogens and make a significant contribution to morbidity and mortality associated with viral diseases. Based on criteria such as host cell specificity, oncogenicity, length of replication cycle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983d4b882d843db3e2731003e87bc938
https://doi.org/10.1128/jvi.74.19.9054-9061.2000

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Amphotropic Murine Leukemia Virus Entry Is Determined by Specific Combinations of Residues from Receptor Loops 2 and 4

Autor: Lene Pedersen, Finn Skou Pedersen, Mikkel Dybro Lundorf, Bryan Mark O'hara

Publikováno v: Lundorf, M, Pedersen, F S, O'Hara, B & Pedersen, L 1999, ' Amphotropic murine leukemia virus entry is determined by specific combinations of residues from receptor loops 2 and 4 ', Journal of Virology, vol. 73, no. 4, pp. 3169-3175 . < http://jvi.asm.org/content/73/4/3169.abstract >

Pit2 is the human receptor for amphotropic murine leukemia virus (A-MuLV); the related human protein Pit1 does not support A-MuLV entry. Interestingly, chimeric proteins in which either the N-terminal or the C-terminal part of Pit2 was replaced by th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddad37bfdfef90131a692d1c0c9257c3
https://doi.org/10.1128/jvi.73.4.3169-3175.1999

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Inhibition of Influenza A Virus Replication by Compounds Interfering with the Fusogenic Function of the Viral Hemagglutinin

Autor: Larocque James Paul, Yakov Gluzman, Stanley A. Lang, Mary Bradley, Ramaswamy Nilakantan, Martin Joseph Digrandi, Bloom Jonathan David, Morin John Edward, Bryan Mark O'hara, Olga Palant, Stephen J. Plotch

Publikováno v: Journal of Virology. 73:140-151

Several compounds that specifically inhibited replication of the H1 and H2 subtypes of influenza virus type A were identified by screening a chemical library for antiviral activity. In single-cycle infections, the compounds inhibited virus-specific p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b2077b272ca0ac8883faf7aecf5c0e
https://doi.org/10.1128/jvi.73.1.140-151.1999

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Localization of the human gene allowing infection by gibbon ape leukemia virus to human chromosome region 2q11-q14 and to the homologous region on mouse chromosome 2

Autor: Bryan Mark O'hara, Neal G. Copeland, Thomas B. Shows, Harold P. Klinger, Nancy A. Jenkins, Margot Kaelbling, Roger L. Eddy, Debra J. Gilbert

Publikováno v: Journal of Virology. 65:1743-1747

Retrovirus receptors remain a largely unexplored group of proteins. Of the receptors which allow infection of human and murine cells by various retroviruses, only three have been identified at the molecular level. These receptors include CD4 for huma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c814335bb260d11beb55d881a130b9
https://doi.org/10.1128/jvi.65.4.1743-1747.1991

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RFI-641, a Potent Respiratory Syncytial Virus Inhibitor

Autor: Antonia A. Nikitenko, Bryan Mark O'hara, Anna Gazumyan, Timothy F. Murphy, Gregory A. Prince, Yuri Raifeld, Philip R. Wyde, Thomas R. Jones, Boris Feld, Clayton C. Huntley, Susan Quartuccio, John O'Connell, Aron Buklan, William J. Weiss, William Hu

Human respiratory syncytial virus (RSV), a paramyxovirus, is a major cause of acute upper and lower respiratory tract infections in infants, young children, and adults. RFI-641 is a novel anti-RSV agent with potent in vitro and in vivo activity. RFI-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef1ec96c3b611aae713cfc22ff578cc
https://europepmc.org/articles/PMC127488/

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Single Amino Acid Insertion in Loop 4 Confers Amphotropic Murine Leukemia Virus Receptor Function upon Murine Pit1

Autor: Finn Skou Pedersen, Lene Pedersen, Bryan Mark O'hara, Mikkel Dybro Lundorf

Publikováno v: Lundorf, M D, Pedersen, F S, O'Hara, B & Pedersen, L 1998, ' Single Amino Acid Insertion in Loop 4 Confers Amphotropic Murine Leukemia Virus Receptor Function upon Murine Pit1 ', Journal of Virology, vol. 75, no. 5, pp. 4524-4527 .

Pit1 is the human receptor for gibbon ape leukemia virus (GALV) and feline leukemia virus subgroup B (FeLV-B), while the related human protein Pit2 is a receptor for amphotropic murine leukemia virus (A-MuLV). The A-MuLV-related isolate 10A1 can util

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020c43e433984b97d3a3c61b7f16f3e2
https://pure.au.dk/portal/da/publications/single-amino-acid-insertion-in-loop-4-confers-amphotropic-murine-leukemia-virus-receptor-function-upon-murine-pit1(7a11b683-e33a-45a6-a73a-6bd3faee2e7a).html

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