Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Bryan Mackowiak"'
Autor:
Seol Hee Park, Wonhyo Seo, Ming-Jiang Xu, Bryan Mackowiak, Yuhong Lin, Yong He, Yaojie Fu, Seonghwan Hwang, Seung-Jin Kim, Yukun Guan, Dechun Feng, Liqing Yu, Richard Lehner, Suthat Liangpunsakul, Bin Gao
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 2, Pp 281-306 (2023)
Background & Aims: Binge drinking in patients with metabolic syndrome accelerates the development of alcohol-associated liver disease. However, the underlying mechanisms remain elusive. We investigated if oxidative and nonoxidative alcohol metabolism
Externí odkaz:
https://doaj.org/article/a67d3ce54aed43fea65cca3f64b06571
Autor:
Robim M. Rodrigues, Yong He, Seonghwan Hwang, Adeline Bertola, Bryan Mackowiak, Yeni Ait Ahmed, Wonhyo Seo, Jing Ma, Xiaolin Wang, Seol Hee Park, Yukun Guan, Yaojie Fu, Tamara Vanhaecke, Dechun Feng, Bin Gao
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 151-171 (2022)
Background & Aims: Nonalcoholic steatohepatitis (NASH) is a leading cause of chronic liver disease, characterized by steatosis and hallmark liver neutrophil infiltration. NASH also is associated with adipose tissue inflammation, but the role of adipo
Externí odkaz:
https://doaj.org/article/9bc1e20fa00e4a4fafdb662818770db4
Autor:
Jing Ma, Adrien Guillot, Zhihong Yang, Bryan Mackowiak, Seonghwan Hwang, Ogyi Park, Brandon J. Peiffer, Ali Reza Ahmadi, Luma Melo, Praveen Kusumanchi, Nazmul Huda, Romil Saxena, Yong He, Yukun Guan, Dechun Feng, Pau Sancho-Bru, Mengwei Zang, Andrew MacGregor Cameron, Ramon Bataller, Frank Tacke, Zhaoli Sun, Suthat Liangpunsakul, Bin Gao
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 14 (2022)
Intrahepatic neutrophil infiltration has been implicated in severe alcoholic hepatitis (SAH) pathogenesis; however, the mechanism underlying neutrophil-induced injury in SAH remains obscure. This translational study aims to describe the patterns of i
Externí odkaz:
https://doaj.org/article/1d54fb8fcbe94219bd2bea490035c8c2
Autor:
Bryan Mackowiak, Bin Gao, MD, PhD
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 343-345 (2022)
Externí odkaz:
https://doaj.org/article/628f4b4406bf441889d7f5d99a657e49
Publikováno v:
Cells, Vol 9, Iss 11, p 2520 (2020)
Non-Hodgkin’s lymphoma (NHL) is a malignant cancer originating in the lymphatic system with a 25–30% mortality rate. CHOP, consisting of cyclophosphamide (CPA), doxorubicin, vincristine, and prednisone, is a first-generation chemotherapy extensiv
Externí odkaz:
https://doaj.org/article/429d3b30522e4ba7844615164546f491
Autor:
Bryan Mackowiak, Bin Gao
Publikováno v:
Hepatology.
Autor:
Bryan Mackowiak, Mingjiang Xu, Yuhong Lin, Yukun Guan, Wonhyo Seo, Ruixue Ren, Dechun Feng, Jace W. Jones, Hongbing Wang, Bin Gao
Publikováno v:
Alcoholism, clinical and experimental researchREFERENCES. 46(12)
The chronic-plus-binge model of ethanol consumption, where chronically (8-week) ethanol-fed mice are gavaged a single dose of ethanol (E8G1), is known to induce steatohepatitis in mice. However, how chronically ethanol-fed mice respond to multiple bi
Autor:
Maureen A. Kane, Ramin Samadani, Lijia Chen, Ramon Martinez, Ivie L. Conlon, Bryan Mackowiak, Paul Shapiro, Kellie Hom, Steven Fletcher, Garrick Centola, Weiliang Huang
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics
Constitutively active extracellular signal-regulated kinase (ERK) 1/2 signaling promotes cancer cell proliferation and survival. We previously described a class of compounds containing a 1,1-dioxido-2,5-dihydrothiophen-3-yl 4-benzenesulfonate scaffol
Autor:
Yaojie Fu, Bryan Mackowiak, Dechun Feng, Hongkun Lu, Yukun Guan, Taylor Lehner, Hongna Pan, Xin Wei Wang, Yong He, Bin Gao
Publikováno v:
Gut. :gutjnl-2022
ObjectiveThe current treatment for hepatocellular carcinoma (HCC) to block angiogenesis and immunosuppression provides some benefits only for a subset of patients with HCC, thus optimised therapeutic regimens are unmet needs, which require a thorough
Autor:
Yaojie Fu, Shanshan Liu, Robim M. Rodrigues, Ying Han, Cao Guo, Zhanwei Zhu, Yong He, Bryan Mackowiak, Dechun Feng, Bin Gao, Shan Zeng, Hong Shen
Publikováno v:
International journal of biological sciences. 18(11)