Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Bryan M. Turner"'
Autor:
John A. Halsall, Simon Andrews, Felix Krueger, Charlotte E. Rutledge, Gabriella Ficz, Wolf Reik, Bryan M. Turner
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Chromatin configuration influences gene expression in eukaryotes at multiple levels, from individual nucleosomes to chromatin domains several Mb long. Post-translational modifications (PTM) of core histones seem to be involved in chromatin s
Externí odkaz:
https://doaj.org/article/638296035c4644d5b4cc65f25c7d7cda
Autor:
Charlotte E. Rutledge, Bryan M. Turner, Wolf Reik, John A. Halsall, Gabriella Ficz, Felix Krueger, Simon Andrews
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Scientific Reports
Scientific Reports
Chromatin configuration influences gene expression in eukaryotes at multiple levels, from individual nucleosomes to chromatin domains several Mb long. Post-translational modifications (PTM) of core histones seem to be involved in chromatin structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2dd1bc6553885059fc83f90db074e7c
Autor:
Manu Araolaza, John A. Halsall, Iraia Muñoa-Hoyos, Carl Ward, Itziar Urizar-Arenaza, Idoia Garcia, Paloma Garcia, Bryan M. Turner, Nerea Subirán, Marta Gianzo
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Clinical Epigenetics
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Clinical Epigenetics
Background Environmentally induced epigenetic changes can lead to health problems or disease, but the mechanisms involved remain unclear. Morphine can pass through the placental barrier leading to abnormal embryo development. However, the mechanism b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cdf401cec3fa811413b6985b4d40b62
http://hdl.handle.net/10810/49987
http://hdl.handle.net/10810/49987
Autor:
Gabriella Ficz, Bryan M. Turner, Wolf Reik, Charlotte E. Rutledge, Felix Krueger, John A. Halsall, Simon Andrews
BackgroundChromatin configuration influences gene expression in eukaryotes at multiple levels, from individual nucleosomes to chromatin domains several Mb long. Post-translational modifications (PTM) of core histones seem to be involved in chromatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7080115b12b609261e6e53c0ee81765
https://doi.org/10.1101/2020.10.16.341446
https://doi.org/10.1101/2020.10.16.341446
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33453 (2012)
Histone deacetylase inhibitors (HDACi) are increasingly used as therapeutic agents, but the mechanisms by which they alter cell behaviour remain unclear. Here we use microarray expression analysis to show that only a small proportion of genes (∼9%)
Externí odkaz:
https://doaj.org/article/807e277a158b4988a06929a0a365d703
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e6086 (2009)
Enzyme-catalyzed, post-translational modifications of core histones have been implicated in the complex changes in gene expression that drive early mammalian development. However, until recently the small number of cells available from the preimplant
Externí odkaz:
https://doaj.org/article/922eb8cc850644baa892133c0cc230e2
Autor:
Hong Lin, Vibhor Gupta, Matthew D Vermilyea, Francesco Falciani, Jeannie T Lee, Laura P O'Neill, Bryan M Turner
Publikováno v:
PLoS Biology, Vol 5, Iss 12, p e326 (2007)
Dosage compensation in mammals involves silencing of one X chromosome in XX females and requires expression, in cis, of Xist RNA. The X to be inactivated is randomly chosen in cells of the inner cell mass (ICM) at the blastocyst stage of development.
Externí odkaz:
https://doaj.org/article/6fe7ef6ab2cd4451b3e80539b38e81cc
Autor:
Bryan M. Turner
Publikováno v:
The Biochemist. 39:4-7
Richard Dawkins' The Selfish Gene was published in 1976. It promulgates a philosophy that places DNA firmly in charge; you are what your DNA (acting in its own evolutionary interests) tells you to be. We know of course that things are not so simple,
Autor:
Bryan M. Turner
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1839:623-626
The nucleosome core particle is the first stage of DNA packaging in virtually all eukaryotes. It both organises nuclear DNA and protects it from adventitious binding of transcription factors and the consequent deregulation of gene expression. Both pr
Autor:
Vineet K. Dhiman, Dominic J. Smiraglia, Prashant Singh, Bryan M. Turner, Craig L. Doig, Moray J. Campbell
Publikováno v:
The Journal of steroid biochemistry and molecular biology
The current study aimed to examine the gene specific mechanisms by which the actions of the vitamin D receptor (VDR) are distorted in prostate cancer. Transcriptional responses toward the VDR ligand, 1α,25(OH)2D3, were examined in non-malignant pros