Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Bryan M Gebhardt"'
Publikováno v:
Drug Design, Development and Therapy, Vol 2009, Iss default, Pp 289-294 (2009)
Bryan M Gebhardt1, Federico Focher2, Richard Eberle3, Andrzej Manikowski4, George E Wright41LSU Eye Center, Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, LA, USA; 2Istituto di Genetica Molecolare, Consig
Externí odkaz:
https://doaj.org/article/992b0e8188eb4fb6a6d0b6fa6bd8080f
Publikováno v:
Drug design, development and therapy
Bryan M Gebhardt1, Federico Focher2, Richard Eberle3, Andrzej Manikowski4, GeorgeE Wright41LSU Eye Center, Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, LA, USA; 2Istituto di Genetica Molecolare, Consigl
Autor:
Silvio Spadari, Andrzej Manikowski, Joseph Gambino, Annalisa Verri, George E. Wright, Andrea Lossani, Bryan M. Gebhardt, Federico Focher
Publikováno v:
Journal of Medicinal Chemistry. 48:3919-3929
Derivatives of the herpes simplex thymidine kinase inhibitor HBPG [2-phenylamino-9-(4-hydroxybutyl)-6-oxopurine] have been synthesized and tested for inhibitory activity against recombinant enzymes (TK) from herpes simplex types 1 and 2 (HSV-1, HSV-2
Autor:
Dass S. Vinay, Hyo Won Jung, James M. Hill, Beom K. Choi, Bryan M. Gebhardt, Byoung S. Kwon, Cho-Rok Jung
Publikováno v:
Current Eye Research. 29:201-208
To determine the effect of ICAM-1 deficiency on viral infection of the cornea.Wild-type and intercellular adhesion molecule 1 (ICAM-1)-deficient mice were infected with the RE strain of herpes simplex virus type 1 (HSV-1). Corneal swabs and trigemina
Publikováno v:
Current Eye Research. 29:119-125
To investigate the effect of acetylsalicylic acid on ocular shedding of herpes simplex virus type 1 (HSV-1).Mice that were latent for the McKrae strain of HSV-1 were treated with acetylsalicylic acid, a nonspecific inhibitor of cyclooxygenases, eithe
Autor:
Emily D. Varnell, Bryan M. Gebhardt, Sang W. Kang, Ho Y. Lim, Shiro Higaki, Herbert E. Kaufman, Su K. Seo, James M. Hill, Byoung S. Kwon
Publikováno v:
European Journal of Immunology. 31:3318-3328
Keratocytes express MHC class I molecules constitutively, and keratocytes stimulated with IFN-gamma express MHC class II molecules. Unstimulated keratocytes constitutively express B7-1 and ICAM-1, as well as low levels of CD40 and 4-1BBL. These findi
Autor:
Bryan M. Gebhardt, James M. Hill, Walter J. Lukiw, Shiro Higaki, Jeannette M. Loutsch, ME Myles, Hilary W. Thompson, Herbert E. Kaufman, Nicolas G. Bazan, Byoung S. Kwon
Publikováno v:
Virus Genes. 23:273-280
An understanding of the cellular genes whose expression is altered during HSV reactivation will enable us to better understand host responses and biochemical pathways involved in the process. Furthermore, this knowledge could allow us to develop gene
Publikováno v:
Transplantation. 67:594-599
Background. In this study, we determined the binding characteristics of F(ab') 2 alloantibody fragments to corneal antigens and assessed the capacity of these antibody fragments to protect corneal allografts from immune attack. Methods. Goat anti-rab
Publikováno v:
Analytical Biochemistry. 266:181-191
The quantitative capacity of the reverse transcription-polymerase chain reaction (RT-PCR) is generally underestimated. In this study, PCR and RT-PCR products were amplified from serially diluted DNA and RNA templates, respectively, using a 35-cycle P
Publikováno v:
Current Eye Research. 16:960-963
PURPOSE. To determine whether substance P is present in human tears. METHODS. Tear samples (1–2 µl) were collected from one eye of each of 12 subjects. Two of the eyes had dry eye syndrome, two wore contact lenses and had dry eye syndrome, and eig