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of 8
pro vyhledávání: '"Bryan Leatham"'
Autor:
Bryan Leatham, Katie McNall, Hari K. K. Subramanian, Lucien Jacky, John Alvarado, Dominic Yurk, Mimi Wang, Donald C. Green, Gregory J. Tsongalis, Aditya Rajagopal, Jerrod J. Schwartz
Publikováno v:
Molecular Oncology, Vol 17, Iss 11, Pp 2221-2234 (2023)
Digital PCR (dPCR) is emerging as an ideal platform for the detection and tracking of genomic variants in cancer due to its high sensitivity and simple workflow. The growing number of clinically actionable cancer biomarkers creates a need for fast, a
Externí odkaz:
https://doaj.org/article/2f8abd2ae9464955898cc183ee988e88
Autor:
Kerri Cabrera, Jeffrey Gole, Bryan Leatham, Matthew J. Springer, Molly Smith, Leah Herdt, Lucien Jacky, Bradley A. Brown
Publikováno v:
Diagnostics, Vol 13, Iss 21, p 3299 (2023)
FDA approval of targeted therapies for lung cancer has significantly improved patient survival rates. Despite these improvements, barriers to timely access to biomarker information, such as nucleic acid input, still exist. Here, we report the analyti
Externí odkaz:
https://doaj.org/article/773e258eb9ce4d119c4e6a1b17eab0ab
BackgroundOver the last ten years, the discovery and FDA approval of targeted therapies for lung cancer has significantly improved patient survival rates. However, despite these improved survival rates, only 68% of patients receive molecular testing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f901a5fd4c229a6d43e8f11b35945c5
https://doi.org/10.1101/2023.05.04.539400
https://doi.org/10.1101/2023.05.04.539400
Autor:
Bryan Leatham, Katie McNall, Hari K. Subramanian, Lucien Jacky, John Alvarado, Dominic Yurk, Mimi Wang, Donald C. Green, Gregory J. Tsongalis, Aditya Rajagopal, Jerrod J. Schwartz
Digital PCR (dPCR) is emerging as an ideal platform for the detection and tracking of genomic variants in cancer due to its high sensitivity and simple workflow. The growing number of clinically-actionable cancer biomarkers creates a need for fast, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a6bedbec7ab8ec54d540ad6f2e1afd7
https://doi.org/10.1101/2023.03.09.531949
https://doi.org/10.1101/2023.03.09.531949
Autor:
Kerri Cabrera, Jeff Gole, Bryan Leatham, Isabel Regoli, Tiffany Martinez, Andrew Richards, Leah Herdt, Juan Enciso, Paige Berroteran, Heather Carolan, Brad Brown
Publikováno v:
Cancer Research. 83:2194-2194
Non-Small Cell Lung Cancer (NSCLC) is the most common type of lung cancer with 236,740 new cases diagnosed in 2022 in the United States. In this study, we demonstrate the performance of a digital PCR (dPCR) based assay that reports 15 (NCCN) biomarke
Autor:
Lucien Jacky, Dominic Yurk, John Alvarado, Bryan Leatham, Jerrod Schwartz, John Annaloro, Chris MacDonald, Aditya Rajagopal
Publikováno v:
Analytical chemistry. 93(51)
Digital PCR (dPCR) is the gold-standard analytical platform for rapid high-precision quantification of genomic fragments. However, current dPCR assays are generally limited to monitoring 1–2 analytes per sample, thereby limiting the platform’s ab
Autor:
Bryan Leatham, Katie McNall, Hari K. Subramanian, John Alvarado, Lucien Jacky, Mimi Wang, Aditya Rajagopal, Jerrod Schwartz
Publikováno v:
Cancer Research. 82:2929-2929
Digital PCR (dPCR) is an emerging platform for detecting genomic variants in cancer genomes due to its high sensitivity and fast time to result compared to massively parallel sequencing. However, translational oncology applications often require the
Autor:
Gregory J. Tsongalis, Bryan Leatham, Katie McNall, Hari Subramanian, John G Alvarado, Lucien Jacky, Dominic Yurk, Donald Green, Aditya Rajagopal, Jerrod Schwartz
Publikováno v:
Journal of Clinical Oncology. 40:e20603-e20603
e20603 Background: Digital PCR (dPCR) is an emerging technology platform for detecting genomic variants in cancer genomes due to its high sensitivity and fast time to results compared to sequencing. However, translational oncology applications often