Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Bryan J. McCullough"'
Autor:
David Douce, Peter Cain, Kirtan Patel, Chris Hopley, Steve Bajic, Bryan J. McCullough, Nicola Lumley, Ryan Francis, Kate Whyatt
Publikováno v:
Journal of the American Society for Mass Spectrometry. 31(2)
The emergence of ambient ionization techniques and their combination with smaller, cheaper mass spectrometers is beginning to make real the possibility of mass spectrometry measurements being made routinely outside of traditional laboratory settings.
Autor:
David Douce, Daniel Burns, Nicola Lumley, Chris Hopley, Simone C. Mathias, Bryan J. McCullough, Steve Bajic, Patrick Sears
Publikováno v:
International Journal of Mass Spectrometry. 471:116735
Five different classes of explosives were analysed by ambient ionisation mass spectrometry testing selectivity, sensitivity, and repeatability. We compare the effectiveness of two techniques (ASAP and SESI) for the trace detection of five explosives
Publikováno v:
Food Chemistry. 245:289-296
The need for an analytical procedure for the identification of allergens present at trace levels in foods was highlighted by conflicting results in a case of contamination of the spice cumin. The application of a bottom-up proteomics experiment was i
Publikováno v:
Forensic Chemistry. 4:75-81
Recent developments in the miniaturisation of mass spectrometry have led to a new generation of low-cost instruments which are making MS a more accessible technology in all areas of analytical science. While the utility of these instruments for quali
Publikováno v:
Rapid communications in mass spectrometry : RCMREFERENCES. 35
RATIONALE As the popularity of ambient ionisation grows, so too does the importance of understanding its capabilities and limitations. The British Mass Spectrometry Society Special Interest Group on Ambient Ionisation has carried out two studies into
Autor:
Christopher J. Welch, Xiaodong Bu, Simon E. Hamilton, Bryan J. McCullough, Fred Mattrey, David Murray
Publikováno v:
Organic Process Research & Development. 18:103-108
In this study we describe the evaluation of a recently developed miniaturized single-quadrupole mass spectrometer to support pharmaceutical process research investigations. Mass spectrometry is becoming an indispensable tool for analytical support of
Autor:
Dominic J. Campopiano, Bryan J. McCullough, Martin De Cecco, Julia R. Dorin, K. J. Taylor, Emily S. Seo, Perdita E. Barran, Derek Macmillan, David Clarke
Publikováno v:
The Journal of Physical Chemistry B. 114:2312-2318
In recent times there has been an enormous rise in resistance to synthetic antibiotics as well as an increase in the virulence of bacteria, the so-called "superbugs". This problem has catalyzed a search for novel molecules to fight bacteria, which in
Autor:
Bryan J. McCullough, Peter Faull, Karoliina E. Korkeila, Jason M. D. Kalapothakis, Andrew Gray, Perdita E. Barran
Publikováno v:
International Journal of Mass Spectrometry. 283:140-148
Gas-phase biomolecular structure may be explored through a number of analytical techniques. Ion mobility-mass spectrometry (IM-MS) continues to prove itself as a sensitive and reliable bioanalytical tool for gas-phase structure determination due to i
Autor:
Bryan J. McCullough, K. J. Taylor, Perdita E. Barran, Julia R. Dorin, Paul Kemper, Derek Macmillan, Jason M. D. Kalapothakis, Hayden Eastwood
Publikováno v:
Analytical Chemistry. 80:6336-6344
We describe here a new ion mobility capable mass spectrometer which comprises a drift cell for mobility separation and a quadrapole time of flight mass spectrometer for mass analysis--the MoQTOF. A commercial QToF instrument (Micromass UK Ltd., Manch
Autor:
Perdita E. Barran, Emily S. Seo, Karen Taylor, Derek Macmillan, De Yang, Julia R. Dorin, John R. W. Govan, Joost J. Oppenheim, Wuthareth Chin, Bryan J. McCullough, David Clarke, Dušan Uhrín, Dominic J. Campopiano
Publikováno v:
Journal of Biological Chemistry. 283:6631-6639
beta-Defensins are important in mammalian immunity displaying both antimicrobial and chemoattractant activities. Three canonical disulfide intramolecular bonds are believed to be dispensable for antimicrobial activity but essential for chemoattractan