Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Bryan J. Lampkin"'
Autor:
Brett VanVeller, Bryan J. Lampkin
Publikováno v:
J Org Chem
Thioamide substitution of backbone peptide bonds can probe interactions along the main chain of proteins. Despite theoretical predictions of the enhanced hydrogen bonding propensities of thioamides, previous studies often do not consider the geometri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fba2cf996587ca9cdaa95c8cbda51f3
https://doi.org/10.1021/acs.joc.1c02373
https://doi.org/10.1021/acs.joc.1c02373
Autor:
Charles Abakah, Jiayuan Miao, Kirsten Deprey, James D. Baleja, Adam Moyer, Bryan J. Lampkin, Jennifer R. Pace, David Baker, Yu-Shan Lin, Joshua A. Kritzer, Robert A. Cerulli
Publikováno v:
J Am Chem Soc
Peptides constrained by intramolecular cross-links, especially stapled α-helices, have emerged as versatile scaffolds for drug development. However, there are fewer examples of similarly constrained scaffolds for other secondary structures. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b2db5b75ccf8e6895ff17249aed574
https://doi.org/10.1021/jacs.1c04378
https://doi.org/10.1021/jacs.1c04378
Publikováno v:
Organic Letters. 21:3817-3821
A new class of push-pull dyes based on the reactive isobenzofuran core have been synthesized. The new dyes have a smaller HOMO-LUMO gap than a related class of dyes based on benzofurazan and allow for isolation of structural factors that contribute t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2249a8275ac1678ed7b3524c5c6179c3
https://doi.org/10.1021/acs.orglett.9b01260
https://doi.org/10.1021/acs.orglett.9b01260
Publikováno v:
Angewandte Chemie (International ed. in English). 59(43)
For many years, Clar's aromatic sextet theory has served as a qualitative method for assessing the aromatic character of polycyclic aromatic hydrocarbons. A new approach, based on the calculation of isotropic magnetic shielding (IMS) contour plots, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56222cda68eaf3617880b3c38058dfc1
https://pubmed.ncbi.nlm.nih.gov/33448542
https://pubmed.ncbi.nlm.nih.gov/33448542
Autor:
Brett VanVeller, Bryan J. Lampkin, Michael P. Hanrahan, Aaron J. Rossini, Scott L. Carnahan, Igor I. Slowing, Gang Wu, Pranjali Naik
Publikováno v:
Journal of the American Chemical Society. 141:441-450
The ubiquity of oxygen in organic, inorganic, and biological systems has stimulated the application and development of 17O solid-state NMR spectroscopy as a probe of molecular structure and dynamic...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10f374629415bc57181d5c292e089134
https://doi.org/10.1021/jacs.8b10878
https://doi.org/10.1021/jacs.8b10878
Autor:
Brett VanVeller, Anuradha V. Wijesekara, Bryan J. Lampkin, Aaron J. Rossini, Ivan Hung, Karthik Nagapudi, Joseph W. Lubach, Zhehong Gan, Peter L. Gor’kov, Amrit Venkatesh
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 26(35)
Fast magic-angle spinning (MAS), frequency selective (FS) heteronuclear multiple quantum coherence (HMQC) experiments which function in an analogous manner to solution SOFAST HMQC NMR experiments, are demonstrated. Fast MAS enables efficient FS excit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad683341f1399a5714bf650d4333aedc
https://pubmed.ncbi.nlm.nih.gov/32315472
https://pubmed.ncbi.nlm.nih.gov/32315472
Autor:
Bryan J. Lampkin, Selin K. Demirci, Caroline C Warner, Sean R Norris, Andrea M Thooft, Brett VanVeller
A new design strategy to control the efficiency of a photocleavage reaction based on changing the nature of the excited state is presented. A novel class of photoactive compounds has been synthesized by combining the classicalo-nitrobenzyl scaffold w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878b33de3a55d5671a97a1bf0f57a3f2
https://aperta.ulakbim.gov.tr/record/8053
https://aperta.ulakbim.gov.tr/record/8053
Publikováno v:
Organic letters. 21(17)
Thioamides are useful biophysical probes for the study of peptide structure and folding. The α-C stereochemistry of thioamide amino acids, however, is easily epimerized during solid-phase peptide synthesis (SPPS), which limits the sequence space tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca723e44f6ce928d1d801768681221c
https://pubmed.ncbi.nlm.nih.gov/31403302
https://pubmed.ncbi.nlm.nih.gov/31403302
A strategy to control the efficiency of a photocleavage reaction based on changing the nature of the excited state is presented. A novel class of photoactive compounds has been synthesized by combining the classical o-nitrobenzyl scaffold with an env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553884320ff765b6e5cfa997f3181ba7
https://doi.org/10.26434/chemrxiv.8251568.v1
https://doi.org/10.26434/chemrxiv.8251568.v1