Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Bryan J. Hoerl"'
Autor:
E. I. Seibel-Ross, R. Sparks, Michael A. Zschunke, Robert E. Scott, Bryan J. Hoerl, Bruce M. Boman, R. Tracy, J. G. Zalitis
Publikováno v:
Cell Proliferation. 23:71-87
Murine mesenchymal stem cells can be induced to arrest their growth at a series of growth and differentiation states in the G1 phase of the cell cycle. These include the predifferentiation arrest state (GD) at which the integrated control of prolifer
Autor:
Chin-Yuan Tzen, David N. Estervig, Parviz Minoo, Peter B. Maercklein, Bryan J. Hoerl, Michiko Filipak, Robert E. Scott
Publikováno v:
Biochemistry and Cell Biology. 66:478-489
Carcinogenesis is a multistep process that results from the development of a variety of defects in the control of differentiation and proliferation. To investigate this concept further, 3T3 T mesenchymal stems cells were employed to establish that a
Autor:
Parviz Minoo, Bryan J. Hoerl, Chin-Yuan Tzen, Michiko Filipak, Michael A. Zschunke, Peter B. Maercklein, Maryanne Edens, David N. Estervig, Robert E. Scott
Publikováno v:
Environmental Health Perspectives
The physiological control of cellular proliferation and differentiation is an integrated regulatory process. This conclusion is based upon observations using numerous in vivo and in vitro experimental systems of which murine BALB/c 3T3 T mesenchymal
Publikováno v:
Journal of Cellular Physiology. 117:249-256
The differentiation of low density BALB/3T3 T proadipocytes that are cultured in standard tissue culture flasks can be induced by heparinized medium containing human plasma. It has been shown that under these conditions, cells first growth-arrest at
Publikováno v:
Experimental cell research. 155(2)
The differentiation of 3T3 T proadipocyte stem cells is controlled at two related yet distinct states in the G1 phase of the cell cycle. They are designated GD and GD'. GD is the G1 state at which cells must growth arrest prior to differentiation, an
Publikováno v:
Journal of cell science. 35
3T3 and SV3T3 mouse embryo cells and a variety of other monolayer cell lines can be induced to form and shed plasma membrane vesicles by exposure to sulphydryl blocking agents including formaldehyde and N-ethyl malemide. Morphological studies show th
Publikováno v:
Cell differentiation. 11(4)
The control of cell proliferation can result from the coupling of growth arrest and differentiation. In this regard, we recently demonstrated that growth arrest which precedes the differentiation of 3T3 T proadipocytes must occur at a distinct state
Autor:
Bruce M. Boman, Bryan J. Hoerl, Douglas E. Swartzendruber, Michael A. Zschunke, Robert E. Scott
Publikováno v:
Experimental cell research. 133(1)
Purified plasma membrane preparations isolated from rapidly growing BALB/3T3 cells have been shown to contain two protein substrates which undergo phosphorylation catalysed by an endogenous cAMP-dependent protein kinase. These substrates, which have
Autor:
Robert E. Scott, Bryan J. Hoerl
Publikováno v:
Journal of cellular physiology. 139(1)
In 3T3 T mesenchymal stem cells, at least four types of biological states exist that can mediate the control of cell differentiation and/or proliferation. These include the predifferentiation growth arrest state, the nonterminal differentiation state
Autor:
Peter B. Maercklein, Parviz Minoo, Chin-Yuan Tzen, Robert E. Scott, David N. Estervig, Bryan J. Hoerl
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 86(5)
The potential of nonterminal cellular differentiation to stably repress the expression of the neoplastic phenotype of transformed cells is established. Nonterminal differentiation induces spontaneously transformed 3T3 T cells to revert to a nontransf