Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Bryan J, Berube"'
Autor:
Sasha E. Larsen, Hazem F. M. Abdelaal, Courtney R. Plumlee, Sara B. Cohen, Ho D. Kim, Holly W. Barrett, Qingyun Liu, Matthew H. Harband, Bryan J. Berube, Susan L. Baldwin, Sarah M. Fortune, Kevin B. Urdahl, Rhea N. Coler
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The three programs that make up the Immune Mechanisms of Protection Against Mycobacterium tuberculosis Centers (IMPAc-TB) had to prioritize and select strains to be leveraged for this work. The CASCADE team based at Seattle Children’s Research Inst
Externí odkaz:
https://doaj.org/article/aeee2ded1b5d4b998456581f74d8ed36
Autor:
Brittany D. Williams, Debora Ferede, Hazem F. M. Abdelaal, Bryan J. Berube, Brendan K. Podell, Sasha E. Larsen, Susan L. Baldwin, Rhea N. Coler
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
At the beginning of the COVID-19 pandemic those with underlying chronic lung conditions, including tuberculosis (TB), were hypothesized to be at higher risk of severe COVID-19 disease. However, there is inconclusive clinical and preclinical data to c
Externí odkaz:
https://doaj.org/article/aff08b3a575940cbbf9ef16b41cab381
Autor:
Sasha E. Larsen, Valerie A. Reese, Tiffany Pecor, Bryan J. Berube, Sarah K. Cooper, Guy Brewer, Diane Ordway, Marcela Henao-Tamayo, Brendan K. Podell, Susan L. Baldwin, Rhea N. Coler
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The nontuberculous mycobacteria (NTM) Mycobacterium avium is a clinically significant pathogen that can cause a wide range of maladies, including tuberculosis-like pulmonary disease. An immunocompromised host status, either genetically or ac
Externí odkaz:
https://doaj.org/article/927dd0386d3f47ee8d7c92fa46bca032
Autor:
Sara E. Maloney, Ian E. Stewart, Brendan K. Podell, Hadley E. Gary, Jeffrey B. Mecham, Bryan J. Berube, Susan L. Baldwin, Rhea N. Coler, Anthony J. Hickey
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 729 (2023)
Mycobacterium tuberculosis (M.tb) has infected one-quarter of the world’s population and led to the deaths of 1.6 million individuals in 2021 according to estimates from the World Health Organization. The rise in prevalence of multidrug-resistant a
Externí odkaz:
https://doaj.org/article/fb1e73021b01468fbe479f08053d7b07
Autor:
Amit P. Khandhar, Chelsea D. Landon, Jacob Archer, Kyle Krieger, Nikole L. Warner, Samantha Randall, Bryan J. Berube, Jesse H. Erasmus, D. Noah Sather, Herman F. Staats
Publikováno v:
Molecular Therapy. 31:1046-1058
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21687fc16ce5ffe00633c5c4c4691618
https://doi.org/10.1016/j.ymthe.2023.02.022
https://doi.org/10.1016/j.ymthe.2023.02.022
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Mycobacterium abscessus infections are increasing worldwide. Current drug regimens are largely ineffective, yet the current development pipeline for M. abscessus is alarmingly sparse. Traditional discovery efforts for M. abscessus assess the capabili
Externí odkaz:
https://doaj.org/article/437e9331002d42c39a0781cd0f871487
Publikováno v:
Toxins, Vol 5, Iss 6, Pp 1140-1166 (2013)
Staphylococcus aureus secretes a number of host-injurious toxins, among the most prominent of which is the small β-barrel pore-forming toxin α-hemolysin. Initially named based on its properties as a red blood cell lytic toxin, early studies suggest
Externí odkaz:
https://doaj.org/article/135dbf2c80db4ab6972e4799681c421d
Autor:
Dara Russell, Lindsay Flint, Catherine Shelton, Bryan J. Berube, Matthew B. McNeil, Tanya Parish, Aaron Korkegian, Yulia Ovechkina
We previously identified a series of triazolopyrimidines with anti-tubercular activity. We determined that Mycobacterium tuberculosis strains with mutations in a component of the cytochrome bc1 system (QcrB) were resistant to the series. A cytochrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e65c5b71c08a88b1126fc2e40deb397f
https://doi.org/10.1101/2021.10.18.464924
https://doi.org/10.1101/2021.10.18.464924
Autor:
Bryan J. Berube, Sasha E. Larsen, Matthew B. McNeil, Valerie A. Reese, Tiffany Pecor, Suhavi Kaur, Tanya Parish, Susan L. Baldwin, Rhea N. Coler
Publikováno v:
Tuberculosis. 137:102272
The increase of global cases of drug resistant (DR) Mycobacterium tuberculosis (M.tb) is a serious problem for the tuberculosis research community and the goals to END TB by 2030. Due to the need for advancing and screening next generation therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf58625f550fb31fb8b107eda0ba19cd
https://doi.org/10.1016/j.tube.2022.102272
https://doi.org/10.1016/j.tube.2022.102272
Autor:
Jaden Yabut, Donald T. Moir, Bryan J. Berube, Alan R. Hauser, Zachary D. Aron, Terry L. Bowlin, John D. Williams, Giang T. Nguyen, Nicholas O. Bowlin, Debra M. Mills, Joan Mecsas
Publikováno v:
Journal of Bacteriology. 202
The Pseudomonas aeruginosa type III secretion system (T3SS) needle comprised of multiple PscF subunits is essential for the translocation of effector toxins into human cells, facilitating the establishment and dissemination of infection. Mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04c45991ca7b0f3d0c0e6b2ebbabbf31
https://doi.org/10.1128/jb.00055-20
https://doi.org/10.1128/jb.00055-20