Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Bryan G Yipp"'
Autor:
Brendan D Snarr, Guillaume St-Pierre, Benjamin Ralph, Mélanie Lehoux, Yukiko Sato, Ann Rancourt, Takahiro Takazono, Shane R Baistrocchi, Rachel Corsini, Matthew P Cheng, Michele Sugrue, Lindsey R Baden, Koichi Izumikawa, Hiroshi Mukae, John R Wingard, Irah L King, Maziar Divangahi, Masahiko S Satoh, Bryan G Yipp, Sachiko Sato, Donald C Sheppard
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008741 (2020)
Aspergillus fumigatus is an opportunistic mold that infects patients who are immunocompromised or have chronic lung disease, causing significant morbidity and mortality in these populations. While the factors governing the host response to A. fumigat
Externí odkaz:
https://doaj.org/article/414657841db046fa861b75d2c1b81a56
Autor:
Andréanne Côté, Chel Hee Lee, Sayed M. Metwaly, Christopher J. Doig, Graciela Andonegui, Bryan G. Yipp, Ken Kuljit S. Parhar, Brent W. Winston
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-11 (2024)
Abstract Background The Berlin definition of acute respiratory distress syndrome (ARDS) includes only clinical characteristics. Understanding unique patient pathobiology may allow personalized treatment. We aimed to define and describe ARDS phenotype
Externí odkaz:
https://doaj.org/article/51696785a6904045808d1662e524495c
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Epithelial host defense to rhinovirus infections is enhanced by targeting the mitochondrial metabolic regulator, PGC-1a. Using metabolomics and proteomics, Michi et al show that human airway epithelial cells mount a barrier-protective early glycolysi
Externí odkaz:
https://doaj.org/article/4ad81efea5d74dc78473dc5ffdbcd650
Autor:
Henrik Almblad, Trevor E. Randall, Fanny Liu, Katherine Leblanc, Ryan A. Groves, Weerayuth Kittichotirat, Geoffrey L. Winsor, Nicolas Fournier, Emily Au, Julie Groizeleau, Jacquelyn D. Rich, Yuefei Lou, Elise Granton, Laura K. Jennings, Larissa A. Singletary, Tara M. L. Winstone, Nathan M. Good, Roger E. Bumgarner, Michael F. Hynes, Manu Singh, Maria Silvina Stietz, Fiona S. L. Brinkman, Ayush Kumar, Ann Karen Cornelia Brassinga, Matthew R. Parsek, Boo Shan Tseng, Ian A. Lewis, Bryan G. Yipp, Justin L. MacCallum, Joe Jonathan Harrison
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility, biofilm production and virulence. Here, the authors identify a thermosensitive enzyme that synthesizes c-di-GMP and modulates temperature-dependent motility, bi
Externí odkaz:
https://doaj.org/article/6182b1bdedda46118764d49013acab00
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The lungs are constantly exposed to non-sterile air which carries harmful threats, such as particles and pathogens. Nonetheless, this organ is equipped with fast and efficient mechanisms to eliminate these threats from the airways as well as prevent
Externí odkaz:
https://doaj.org/article/a8ba47e3123a4868aad8a3500cc10d08
Autor:
Nicole Sarden, Bryan G. Yipp
Publikováno v:
Trends in Immunology. 44:305-318
Autor:
Mark R. Gillrie, Nicole Rosin, Sarthak Sinha, Hellen Kang, Raquel Farias, Angela Nguyen, Kelsie Volek, Jordan Mah, Etienne Mahe, Marvin J. Fritzler, Bryan G. Yipp, Jeff Biernaskie
Publikováno v:
Frontiers in Immunology. 14
Despite surviving a SARS-CoV-2 infection, some individuals experience an intense post-infectious Multisystem Inflammatory Syndrome (MIS) of uncertain etiology. Children with this syndrome (MIS-C) can experience a Kawasaki-like disease, but mechanisms
Autor:
Nicole Sarden, Sarthak Sinha, Kyle G. Potts, Erwan Pernet, Carlos H. Hiroki, Mortaza F. Hassanabad, Angela P. Nguyen, Yuefei Lou, Raquel Farias, Brent W. Winston, Amy Bromley, Brendan D. Snarr, Amanda Z. Zucoloto, Graciela Andonegui, Daniel A. Muruve, Braedon McDonald, Donald C. Sheppard, Douglas J. Mahoney, Maziar Divangahi, Nicole Rosin, Jeff Biernaskie, Bryan G. Yipp
Publikováno v:
Science Translational Medicine. 14
The lung naturally resists Aspergillus fumigatus ( Af ) in healthy individuals, but multiple conditions can disrupt this resistance, leading to lethal invasive infections. Core processes of natural resistance and its breakdown are undefined. We inves
Autor:
Antoine Dufour, Raquel Farias, Leslie Cao, Mark R. Gillrie, Braedon McDonald, Bryan G. Yipp, Nicole L. Rosin, Angela P. Nguyen, Arzina Jaffer, Elodie Labit, Sarthak Sinha, Amy Bromley, Luiz Gustavo de Almeida, Jeff Biernaskie, Marvin J. Fritzler, Rohit Arora
Publikováno v:
Nature Reviews. Immunology
Nature Medicine
Nature Medicine
Although critical for host defense, innate immune cells are also pathologic drivers of acute respiratory distress syndrome (ARDS). Innate immune dynamics during Coronavirus Disease 2019 (COVID-19) ARDS, compared to ARDS from other respiratory pathoge
Autor:
Luke Brown, Bryan G. Yipp
Publikováno v:
Nature cardiovascular research. 1(8)
Thrombocytopenia is common in severe sepsis and is associated with an increased risk of mortality. A new study shows that platelet pyroptosis initiated during infection promotes a feedforward loop of neutrophil-mediated inflammation that worsens outc