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The Target Selects the Toxin: Specific Amino Acids in Snake-Prey Nicotinic Acetylcholine Receptors That Are Selectively Bound by King Cobra Venoms

Autor: Richard Harris, Uthpala Madhavi Chandrasekara, Bryan Fry

Publikováno v: Toxins; Volume 14; Issue 8; Pages: 528

Snake venom is an adaptive ecological trait that has evolved primarily as a form of prey subjugation. Thus, the selection pressure for toxin diversification is exerted by the prey’s physiological targets, with this pressure being particularly acute

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4660b49064ae27573f6fff54d8e3dcda
https://pubmed.ncbi.nlm.nih.gov/36006190

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Influence of Study Composition on the Efficacy of Sleep Detection Using Actigraphy

Autor: Kevin Chao, Bryan Fry, Kuldeep Singh Rajput, Nandakumar Selvaraj

Publikováno v: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2021

Wearable actigraphy sensors have been useful tools for unobtrusive monitoring of sleep. The influence of the composition and characteristics of study groups such as normal sleep versus sleep disorders affecting the efficacy of sleep assessment using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20173b0fe1d86c4d9512e56c761090b
https://pubmed.ncbi.nlm.nih.gov/34892834

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Elektronická kniha

Venomous Reptiles and Their Toxins : Evolution, Pathophysiology and Biodiscovery

Autor: Bryan Fry

Venom research and technology has advanced greatly, rapidly transforming our knowledge of reptile venoms. Research advances, like the development of molecular systematics, provide the framework necessary to reconstruct the evolutionary history of gla

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The origin and evolution of the Toxicofera reptile venom system

Autor: Bryan Fry, Kartik Sunagar, Nicolas Casewell, Elazar Kochva, Holger Scheib, Wolfgang Wüster, Nicolas Vidal, Bruce Young, Frank Burbrink, Alexander Pyron, Freek Vonk, Kim Roelants, Timothy Jackson

Publikováno v: Vrije Universiteit Brussel

The insights gained into the contentious evolutionary history of the venom system of toxicoferan reptiles (Serpentes [snakes] plus Anguimorpha [anguimorph lizards] and Iguania [iguanian lizards]) in recent years have generated considerable controvers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9af9435075f2e5f25f01a7d483743d08
https://biblio.vub.ac.be/vubir/the-origin-and-evolution-of-the-toxicofera-reptile-venom-system(003ce73c-474e-4076-8bf3-31716c739f14).html

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Exendin peptides

Autor: Bryan Fry, Timothy Jackson, Kim Roelants, Kartik Sunagar, Zoltan Takacs, Timothy Reeks, Hang Fai Kwok

Publikováno v: Vrije Universiteit Brussel

Exendin peptides are not only the most enigmatic of all toxins, but they are also among the most medically useful. Their genetic ancestry remains to be conclusively resolved, but the evidence and the principle of parsimony point toward a single evolu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8d059384aaee6d13c77867553b2a6a99
https://biblio.vub.ac.be/vubir/exendin-peptides(e8f52e24-5f8d-498f-a3e9-4025d847fd52).html

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Tentacles of venom: toxic protein convergence in the Kingdom Animalia

Autor: Bryan Fry, Kim Roelants, Jannette Norman

Publikováno v: Vrije Universiteit Brussel

The origin and evolution of venom in many animal orders remain controversial or almost entirely uninvestigated. Here we use cDNA studies of cephalopod posterior and anterior glands to reveal a single early origin of the associated secreted proteins.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::55ee6bf3fde15962a4b3839489148b24
https://biblio.vub.ac.be/vubir/tentacles-of-venom-toxic-protein-convergence-in-the-kingdom-animalia(1fae4f4f-6182-43f6-8005-3eec327c5785).html

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The toxicogenomic multiverse: convergent recruitment of proteins into animal venoms

Autor: Bryan Fry, Kim Roelants, Donald Champagne, Holger Scheib, Joel Tyndall, Glenn King, Timo Nevalainen, Jannette Norman, Richard Lewis, Raymond Norton, Camila Renjifo, Ricardo De La Vega

Publikováno v: Vrije Universiteit Brussel

Throughout evolution, numerous proteins have been convergently recruited into the venoms of various animals, including centipedes, cephalopods, cone snails, fish, insects (several independent venom systems), platypus, scorpions, shrews, spiders, toxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6d83fdab40b69cc2a8c74a4cfa8df022
https://hdl.handle.net/20.500.14017/92fc9495-cf1a-46e8-9e79-148e80cd1738

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