Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Bryan France"'
Autor:
Cody J. Aros, Manash K. Paul, Carla J. Pantoja, Bharti Bisht, Luisa K. Meneses, Preethi Vijayaraj, Jenna M. Sandlin, Bryan France, Jonathan A. Tse, Michelle W. Chen, David W. Shia, Tammy M. Rickabaugh, Robert Damoiseaux, Brigitte N. Gomperts
Publikováno v:
Cell Reports, Vol 30, Iss 7, Pp 2055-2064.e5 (2020)
Summary: Mechanisms underpinning airway epithelial homeostatic maintenance and ways to prevent its dysregulation remain elusive. Herein, we identify that β-catenin phosphorylated at Y489 (p-β-cateninY489) emerges during human squamous lung cancer p
Externí odkaz:
https://doaj.org/article/a599394ed7284d46981ea5a3afde29bc
Autor:
Jeremiah Olorunjuwon Olugbami, Robert Damoiseaux, Bryan France, Esther Modupe Onibiyo, Michael Adedapo Gbadegesin, Shivani Sharma, James Kazimierz Gimzewski, Oyeronke Adunni Odunola
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 17, Iss 1, Pp 1-11 (2017)
Abstract Background Epidemiological and experimental evidences have shown cancer as a leading cause of death worldwide. Although the folklore use of plants as a reliable source of health-restoring principles is well-documented, the search for more of
Externí odkaz:
https://doaj.org/article/8d2eb97e04c34d9c806459cded173851
Autor:
Jill K Terra, Bryan France, Christopher K Cote, Amy Jenkins, Joel A Bozue, Susan L Welkos, Ragini Bhargava, Chi-Lee Ho, Margarete Mehrabian, Calvin Pan, Aldons J Lusis, Richard C Davis, Steven M LeVine, Kenneth A Bradley
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002469 (2011)
Anthrax is a potentially fatal disease resulting from infection with Bacillus anthracis. The outcome of infection is influenced by pathogen-encoded virulence factors such as lethal toxin (LT), as well as by genetic variation within the host. To ident
Externí odkaz:
https://doaj.org/article/268629d88df4443393b3b819c4cfb5ee
Autor:
Philip L. Bulterys, Isabelle J. Toesca, Michael H. Norris, Jeffrey P. Maloy, Sorel T. Fitz-Gibbon, Bryan France, Babak Toffig, Marco Morselli, Nawarat Somprasong, Matteo Pellegrini, Herbert P. Schweizer, Apichai Tuanyok, Robert Damoiseaux, Christopher T. French, Jeff F. Miller
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Burkholderia pseudomallei, the etiologic agent of melioidosis, is an environmental organism that inhabits tropical soils and kills an estimated 90,000 people each year. Caused by an intracellular and often drug-resistant pathogen, melioi
Publikováno v:
Environmental and Molecular Mutagenesis. 58:522-528
Genotoxicity is thought to be the cause of many cancers. Genotoxicity due to environmental toxins may be partly responsible for the dramatic increase in the incidence of papillary thyroid cancer over the past two decades. Here, we present a fully aut
Autor:
Ivan Pushkarsky, Peter Tseng, Dylan Black, Bryan France, Lyndon Warfe, Cynthia J. Koziol-White, William F. Jester, Ryan K. Trinh, Jonathan Lin, Philip O. Scumpia, Sherie L. Morrison, Reynold A. Panettieri, Robert Damoiseaux, Dino Di Carlo
Publikováno v:
Nature biomedical engineering, vol 2, iss 2
As cells with aberrant force-generating phenotypes can directly lead to disease, cellular force-generation mechanisms are high-value targets for new therapies. Here, we show that single-cell force sensors embedded in elastomers enable single-cell for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c573d2908625d9f6789550cfa46a9a24
https://escholarship.org/uc/item/9tx782d1
https://escholarship.org/uc/item/9tx782d1
Autor:
Yu-Chen Lo, Silvia Senese, Bryan France, Ankur A. Gholkar, Robert Damoiseaux, Jorge Z. Torres
Publikováno v:
Scientific reports, vol 7, iss 1
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Lo, Y-C; Senese, S; France, B; Gholkar, AA; Damoiseaux, R; & Torres, JZ. (2017). Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential. SCIENTIFIC REPORTS, 7. doi: 10.1038/s41598-017-11508-2. UCLA: Retrieved from: http://www.escholarship.org/uc/item/0p64d8z3
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Lo, Y-C; Senese, S; France, B; Gholkar, AA; Damoiseaux, R; & Torres, JZ. (2017). Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential. SCIENTIFIC REPORTS, 7. doi: 10.1038/s41598-017-11508-2. UCLA: Retrieved from: http://www.escholarship.org/uc/item/0p64d8z3
Discovery of first-in-class medicines for treating cancer is limited by concerns with their toxicity and safety profiles, while repurposing known drugs for new anticancer indications has become a viable alternative. Here, we have developed a new appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef30954cf72900e2d2eb7083c2b18e8
https://escholarship.org/uc/item/0p64d8z3
https://escholarship.org/uc/item/0p64d8z3
Autor:
Rong Liu, Bryan France, Saji George, Robert Rallo, Haiyuan Zhang, Tian Xia, Andre E. Nel, Kenneth Bradley, Yoram Cohen
Publikováno v:
Analyst
Repositori Institucional de la Universitat Rovira i Virgili
Universitat Rovira i virgili (URV)
Repositori Institucional de la Universitat Rovira i Virgili
Universitat Rovira i virgili (URV)
Relationships among fourteen different biological responses (including ten signaling pathway activities and four cytotoxicity effects) of murine macrophage (RAW264.7) and bronchial epithelial (BEAS-2B) cells exposed to six metal and metal oxide nanop
Autor:
Jason L. Larabee, Francisco J. Maldonado-Arocho, Sergio Pacheco, Bryan France, Kevin DeGiusti, Salika M. Shakir, Kenneth A. Bradley, Jimmy D. Ballard
Publikováno v:
Infection and Immunity. 79:3302-3308
Anthrax edema toxin (ET) is one of two binary toxins produced by Bacillus anthracis that contributes to the virulence of this pathogen. ET is an adenylate cyclase that generates high levels of cyclic AMP (cAMP), causing alterations in multiple host c
Autor:
Robert Rallo, Bryan France, Rong Liu, Sumitra Nair, Saji George, Robert Damoiseaux, Francesc Giralt, Andre Nel, Kenneth Bradley, Yoram Cohen
Publikováno v:
Environmental Science & Technology. 45:1695-1702
The response of a murine macrophage cell line exposed to a library of seven metal and metal oxide nanoparticles was evaluated via High Throughput Screening (HTS) assay employing luciferase-reporters for ten independent toxicity-related signaling path