Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Bryan Faust"'
Autor:
Roberto Efraín Díaz, Andrew K Ecker, Galen J Correy, Pooja Asthana, Iris D Young, Bryan Faust, Michael C Thompson, Ian B Seiple, Steven Van Dyken, Richard M Locksley, James S Fraser
Publikováno v:
eLife, Vol 12 (2024)
Chitin is an abundant biopolymer and pathogen-associated molecular pattern that stimulates a host innate immune response. Mammals express chitin-binding and chitin-degrading proteins to remove chitin from the body. One of these proteins, Acidic Mamma
Externí odkaz:
https://doaj.org/article/1d6ac3d5e2914957b1f145449e49bd88
Autor:
Kristyn Hayashi, Kenton L. Longenecker, Yi-Liang Liu, Bryan Faust, Aditi Prashar, Johannes Hampl, Vincent Stoll, Sandro Vivona
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Melanotransferrin (MTf) is an iron-binding member of the transferrin superfamily that can be membrane-anchored or secreted in serum. On cells, it can mediate transferrin-independent iron uptake and promote proliferation. In serum, it is a tr
Externí odkaz:
https://doaj.org/article/e40faf28a7d64f9d868ff1e3a76c9fde
Autor:
Christian B. Billesbølle, Claire A. de March, Wijnand J. C. van der Velden, Ning Ma, Jeevan Tewari, Claudia Llinas del Torrent, Linus Li, Bryan Faust, Nagarajan Vaidehi, Hiroaki Matsunami, Aashish Manglik
Our sense of smell enables us to navigate a vast space of chemically diverse odor molecules. This task is accomplished by the combinatorial activation of approximately 400 olfactory G protein-coupled receptors (GPCRs) encoded in the human genome1–3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b631cd2538099921fc927df0be52bc6
https://doi.org/10.1101/2022.12.20.520951
https://doi.org/10.1101/2022.12.20.520951
Autor:
Marc A. Dämgen, David M. Thal, Ron O. Dror, Arisbel B. Gondin, Julian A Harris, Yifan Cheng, Carl-Mikael Suomivuori, Nicholas A. Veldhuis, Bryan Faust, Aashish Manglik
Publikováno v:
Nature Chemical Biology. 18:109-115
The neuropeptide substance P (SP) is important in pain and inflammation. SP activates the neurokinin-1 receptor (NK1R) to signal via Gq and Gs proteins. Neurokinin A also activates NK1R, but leads to selective Gq signaling. How two stimuli yield dist
Autor:
Bryan Faust, Christian B. Billesbølle, Carl-Mikael Suomivuori, Isha Singh, Kaihua Zhang, Nicholas Hoppe, Antonio F. M. Pinto, Jolene K. Diedrich, Yagmur Muftuoglu, Mariusz W. Szkudlinski, Alan Saghatelian, Ron O. Dror, Yifan Cheng, Aashish Manglik
Publikováno v:
Nature, vol 609, iss 7928
Nature
Nature
Thyroid hormones are vital in metabolism, growth and development(1). Thyroid hormone synthesis is controlled by thyrotropin (TSH), which acts at the thyrotropin receptor (TSHR)(2). In patients with Graves’ disease, autoantibodies that activate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c970e589a202254df5f2423c80112e
https://escholarship.org/uc/item/7xj7c9w5
https://escholarship.org/uc/item/7xj7c9w5
Autor:
Bryan Faust, Isha Singh, Kaihua Zhang, Nicholas Hoppe, Antonio F. M. Pinto, Yagmur Muftuoglu, Christian B. Billesbølle, Alan Saghatelian, Yifan Cheng, Aashish Manglik
Thyroid hormones are vital to growth and metabolism. Thyroid hormone synthesis is controlled by thyrotropin (TSH), which acts at the thyrotropin receptor (TSHR). Autoantibodies that activate the TSHR pathologically increase thyroid hormones in Graves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::404c6ee9e0d36765991c0511ff4db451
https://doi.org/10.1101/2022.01.06.475289
https://doi.org/10.1101/2022.01.06.475289
Autor:
J.A. Harris, Ron O. Dror, Bryan Faust, David M. Thal, Arisbel B. Gondin, Carl-Mikael Suomivuori, Nicholas A. Veldhuis, Marc A. Dämgen, Aashish Manglik, Yifan Cheng
The neuropeptide Substance P (SP) is important in pain and inflammation. SP activates the neurokinin-1 receptor (NK1R) to signal via Gqand Gsproteins. Neurokinin A also activates NK1R, but leads to selective Gqsignaling. How two stimuli yield distinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3b7fec6b58b262a835dddeaf60928c4
https://doi.org/10.1101/2021.05.16.444192
https://doi.org/10.1101/2021.05.16.444192
Autor:
Johannes Hampl, Yi-Liang Liu, Vincent S. Stoll, Aditi Prashar, Sandro Vivona, Kenton L. Longenecker, Kristyn Hayashi, Bryan Faust
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
Melanotransferrin (MTf) is an iron-binding member of the transferrin superfamily that can be membrane-anchored or secreted in serum. On cells, it can mediate transferrin-independent iron uptake and promote proliferation. In serum, it is a transcytoti
Autor:
Bei Wang, Daniel Asarnow, Wen-Hsin Lee, Ching-Wen Huang, Bryan Faust, Patricia Miang Lon Ng, Eve Zi Xian Ngoh, Markus Bohn, David Bulkley, Andrés Pizzorno, Hwee Ching Tan, Chia Yin Lee, Rabiatul Adawiyah Minhat, Olivier Terrier, Mun Kuen Soh, Frannie Jiuyi Teo, Yvonne Yee Chin Yeap, Yuanyu Hu, Shirley Gek Kheng Seah, Sebastian Maurer-Stroh, Laurent Renia, Brendon John Hanson, Manuel Rosa-Calatrava, Aashish Manglik, Yifan Cheng, Charles S. Craik, Cheng-I Wang
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
In vitro antibody selection against pathogens from naïve combinatorial libraries can yield various classes of antigen-specific binders that are distinct from those evolved from natural infection1–4. Also, rapid neutralizing antibody discovery can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38885bd9bef5c4aadb645f8ff2e2baf
https://hal.science/hal-02988332/file/2020.07.14.203414v1.full.pdf
https://hal.science/hal-02988332/file/2020.07.14.203414v1.full.pdf
Autor:
Un Seng Chio, Ming Sun, Adolfo García-Sastre, R.A. Saunders, Niv Dobzinski, Jiahao Liang, Vladislav Belyy, Peter Walter, Caleigh M. Azumaya, Beth S. Zha, Fei Li, Morgane Boone, Kris M. White, Yuwei Liu, Kaitlin Schaefer, Frank R. Moss, Aashish Manglik, Nevan J. Krogan, Michael C. Thompson, Nick Hoppe, Alexandrea N. Rizo, Axel F. Brilot, Danielle L. Swaney, S. Dickinson, Corie Y. Ralston, Bryan Faust, Devan Diwanji, A.W. Barile-Hill, Camille R. Simoneau, Smriti Sangwan, Sayan Gupta, Benjamin Barsi-Rhyne, Mingliang Jin, Veronica V. Rezelj, Huong T. Kratochvil, Silke Nock, David Bulkley, Kristoffer E. Leon, Marco Vignuzzi, Sergei Pourmal, Henry C. Nguyen, Thomas H. Pospiech, Gregory E. Merz, Raphael Trenker, Cynthia M. Chio, Yanxin Liu, Kaihua Zhang, Meghna Gupta, Aditya A. Anand, Cristina Puchades, M. Zimanyi, Amber M. Smith, Michael Schoof, Christian B. Billesbølle, Melanie Ott, Ishan Deshpande
Publikováno v:
Science (New York, N.y.)
Science
Science
Nanobodies that neutralize Monoclonal antibodies that bind to the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) show therapeutic promise but must be produced in mammalian cells and need to be delivered intravenously. B