Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Bryan E Welm"'
Autor:
Jessica Maddox, Arvind Shakya, Samuel South, Dawne Shelton, Jared N Andersen, Stephanie Chidester, Jinsuk Kang, Keith M Gligorich, David A Jones, Gerald J Spangrude, Bryan E Welm, Dean Tantin
Publikováno v:
PLoS Genetics, Vol 8, Iss 11, p e1003048 (2012)
Defining master transcription factors governing somatic and cancer stem cell identity is an important goal. Here we show that the Oct4 paralog Oct1, a transcription factor implicated in stress responses, metabolic control, and poised transcription st
Externí odkaz:
https://doaj.org/article/0919bdc7bcae48b0ba2c398df15a22d4
Autor:
Sandra D. Scherer, Ling Zhao, Andrew J. Butterfield, Chieh-Hsiang Yang, Emilio Cortes-Sanchez, Katrin P. Guillen, Bryan E. Welm, Alana L. Welm
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102402- (2023)
Summary: Patient-derived xenografts (PDXs) have clinical value but are time-, cost-, and labor-intensive and thus ill-suited for large-scale experiments. Here, we present a protocol to convert PDX tumors into PDxOs for long-term cultures amenable to
Externí odkaz:
https://doaj.org/article/caabe65db8564dada1e80756fb6070c9
Autor:
Varduhi Petrosyan, Lacey E. Dobrolecki, Lillian Thistlethwaite, Alaina N. Lewis, Christina Sallas, Ramakrishnan R. Srinivasan, Jonathan T. Lei, Vladimir Kovacevic, Predrag Obradovic, Matthew J. Ellis, C. Kent Osborne, Mothaffar F. Rimawi, Anne Pavlick, Maryam Nemati Shafaee, Heidi Dowst, Antrix Jain, Alexander B. Saltzman, Anna Malovannaya, Elisabetta Marangoni, Alana L. Welm, Bryan E. Welm, Shunqiang Li, Gerburg M. Wulf, Olmo Sonzogni, Chen Huang, Suhas Vasaikar, Susan G. Hilsenbeck, Bing Zhang, Aleksandar Milosavljevic, Michael T. Lewis
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105799- (2023)
Summary: Although systemic chemotherapy remains the standard of care for TNBC, even combination chemotherapy is often ineffective. The identification of biomarkers for differential chemotherapy response would allow for the selection of responsive pat
Externí odkaz:
https://doaj.org/article/2b0f86504c374089a6c4e5c09a09e1cb
Autor:
Hua Sun, Song Cao, R. Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C. Wendl, Sherri R. Davies, Matthew H. Bailey, Tina M. Primeau, Jeremy Hoog, Jacqueline L. Mudd, Dennis A. Dean, Rajesh Patidar, Li Chen, Matthew A. Wyczalkowski, Reyka G. Jayasinghe, Fernanda Martins Rodrigues, Nadezhda V. Terekhanova, Yize Li, Kian-Huat Lim, Andrea Wang-Gillam, Brian A. Van Tine, Cynthia X. Ma, Rebecca Aft, Katherine C. Fuh, Julie K. Schwarz, Jose P. Zevallos, Sidharth V. Puram, John F. Dipersio, The NCI PDXNet Consortium, Brandi Davis-Dusenbery, Matthew J. Ellis, Michael T. Lewis, Michael A. Davies, Meenhard Herlyn, Bingliang Fang, Jack A. Roth, Alana L. Welm, Bryan E. Welm, Funda Meric-Bernstam, Feng Chen, Ryan C. Fields, Shunqiang Li, Ramaswamy Govindan, James H. Doroshow, Jeffrey A. Moscow, Yvonne A. Evrard, Jeffrey H. Chuang, Benjamin J. Raphael, Li Ding
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Patient-derived xenograft models (PDX) have been extensively used to study the molecular and clinical features of cancers. Here the authors present a cohort of 536 PDX models from 25 cancers, as well as their genomic and evolutionary profiles and the
Externí odkaz:
https://doaj.org/article/e6286532f9bc487a87943a142621d7a3
Autor:
Blake R. Wilde, Mohan R. Kaadige, Katrin P. Guillen, Andrew Butterfield, Bryan E. Welm, Donald E. Ayer
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background Protein synthesis is regulated by the availability of amino acids, the engagement of growth factor signaling pathways, and adenosine triphosphate (ATP) levels sufficient to support translation. Crosstalk between these inputs is ex
Externí odkaz:
https://doaj.org/article/c974fd6b85e94429a1a2e9d12bfd477a
Publikováno v:
APL Bioengineering, Vol 5, Iss 2, Pp 029901-029901-1 (2021)
Externí odkaz:
https://doaj.org/article/dfdb34176d4a4fdebc71b818ec438fba
Publikováno v:
APL Bioengineering, Vol 5, Iss 1, Pp 010901-010901-4 (2021)
Human cancer is a complex and heterogeneous collection of diseases that kills more than 18 million people every year worldwide. Despite advances in detection, diagnosis, and treatments for cancers, new strategies are needed to combat deadly cancer
Externí odkaz:
https://doaj.org/article/b02723fc989a45c395ca5f612404f280
Autor:
Hua Sun, Song Cao, R. Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C. Wendl, Sherri R. Davies, Matthew H. Bailey, Tina M. Primeau, Jeremy Hoog, Jacqueline L. Mudd, Dennis A. Dean, Rajesh Patidar, Li Chen, Matthew A. Wyczalkowski, Reyka G. Jayasinghe, Fernanda Martins Rodrigues, Nadezhda V. Terekhanova, Yize Li, Kian-Huat Lim, Andrea Wang-Gillam, Brian A. Van Tine, Cynthia X. Ma, Rebecca Aft, Katherine C. Fuh, Julie K. Schwarz, Jose P. Zevallos, Sidharth V. Puram, John F. Dipersio, The NCI PDXNet Consortium, Brandi Davis-Dusenbery, Matthew J. Ellis, Michael T. Lewis, Michael A. Davies, Meenhard Herlyn, Bingliang Fang, Jack A. Roth, Alana L. Welm, Bryan E. Welm, Funda Meric-Bernstam, Feng Chen, Ryan C. Fields, Shunqiang Li, Ramaswamy Govindan, James H. Doroshow, Jeffrey A. Moscow, Yvonne A. Evrard, Jeffrey H. Chuang, Benjamin J. Raphael, Li Ding
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/395184e65c5746b0adbbaf31dc3c4cc4
Autor:
Jeffery M. Vahrenkamp, Chieh-Hsiang Yang, Adriana C. Rodriguez, Aliyah Almomen, Kristofer C. Berrett, Alexis N. Trujillo, Katrin P. Guillen, Bryan E. Welm, Elke A. Jarboe, Margit M. Janat-Amsbury, Jason Gertz
Publikováno v:
Cell Reports, Vol 22, Iss 11, Pp 2995-3005 (2018)
Summary: Steroid hormone receptors are simultaneously active in many tissues and are capable of altering each other’s function. Estrogen receptor α (ER) and glucocorticoid receptor (GR) are expressed in the uterus, and their ligands have opposing
Externí odkaz:
https://doaj.org/article/373a73b79ed044d69306f26432b18e84
Autor:
Clinton C. Mason, Josef T. Prchal, Lynn B. Jorde, Christopher Ours, Juan L. Rodriguez-Flores, Bryan E. Welm, Amber Ferdig, Chad VanSant-Webb, Monika J. Baker, Tsewang Tashi, Sasi Arunachalam, Julie E. Feusier
Hotspots difficult to confidently assess for CHIP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87246a984ac3872eac03ad48384c025b
https://doi.org/10.1158/2643-3230.22543200
https://doi.org/10.1158/2643-3230.22543200