Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bryan E Hoffman"'
Autor:
Elizabeth B. Somers, Zoltan Dezso, Natalie C. Twine, Daniel J. O'Shannessy, Bryan E Hoffman, Sergei Agoulnik, Stephen M. Jackson
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 7, Pp 13687-13703 (2013)
International Journal of Molecular Sciences; Volume 14; Issue 7; Pages: 13687-13703
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 14; Issue 7; Pages: 13687-13703
International Journal of Molecular Sciences
Folate receptor alpha (FOLR1/FRA) is reported to be overexpressed in epithelial ovarian cancers (EOC), especially the serous histotype. Further, while dysregulation of the folate-dependent 1-carbon cycle has been implicated in tumorogenesis, little i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d129a082d99723e58915696023751c
http://www.mdpi.com/1422-0067/14/7/13687
http://www.mdpi.com/1422-0067/14/7/13687
Autor:
Ping Zhang, Yi Shi, Damir Hamamdzic, Christine L. Webb, Daniel J Pelchovitz, M Walker, Jun Li, Mark E. Burgert, LeFeng Zhang, Jisheng Yang, Anthony D. Postle, Rosanna C. Mirabile, Emile R. Mohler, Bryan E. Hoffman, Andrew Zalewski, Robert S. Fenning, Robert L. Wilensky, James G. Bollinger, Michael H. Gelb, Colin H. Macphee
Publikováno v:
Nature Medicine. 14:1059-1066
Increased lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) activity is associated with increased risk of cardiac events, but it is not known whether Lp-PLA(2) is a causative agent. Here we show that selective inhibition of Lp-PLA(2) with darapla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6915a97a72bbe230c5da0785b9f94d0
https://doi.org/10.1038/nm.1870
https://doi.org/10.1038/nm.1870
Autor:
Gretchen Temeles, Jinshui Fan, Stefanie Galbán, Jennifer L. Martindale, Bryan E. Hoffman, Chris Cheadle, Myriam Gorospe, Jochen Decker, Michael P. Woods, Jürgen Brieger
Publikováno v:
Molecular and Cellular Biology. 23:2316-2328
Based on evidence that the von Hippel-Lindau (VHL) tumor suppressor protein is associated with polysomes and interacts with translation regulatory factors, we set out to investigate the potential influence of pVHL on protein translation. To this end,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae047109313d43431622a01de05c823
https://doi.org/10.1128/mcb.23.7.2316-2328.2003
https://doi.org/10.1128/mcb.23.7.2316-2328.2003
Autor:
John T. Lis, Bryan E. Hoffman
Publikováno v:
Molecular and Cellular Biology. 20:181-186
Many genes are interrupted by introns that are removed in the process of making a functional mRNA and, ultimately, a protein product. This splicing process takes place in a megadalton RNA-protein complex termed the spliceosome. The spliceosome consis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c3a8d50189dd123efd667cd6be9c3f
https://doi.org/10.1128/mcb.20.1.181-186.2000
https://doi.org/10.1128/mcb.20.1.181-186.2000
Publikováno v:
Molecular and Cellular Biology. 17:2649-2657
B52, also known as SRp55, is a member of the Drosophila melanogaster SR protein family, a group of nuclear proteins that are both essential splicing factors and specific splicing regulators. Like most SR proteins, B52 contains two RNA recognition mot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3934184ba3bbf970f64a36cf49d4af21
https://doi.org/10.1128/mcb.17.5.2649
https://doi.org/10.1128/mcb.17.5.2649
Autor:
Tonie M. Newman-Tarr, Ryan J. Boyle, Bryan E. Hoffman, Anna Gibbard, Charles Hanning, Sanjay Kumar, Shen Wang, Manas K. Majumdar, Michael A. Pratta
Publikováno v:
Journal of Cellular Physiology.
Chondrocytes, the only cell type present in articular cartilage, regulate tissue homeostasis by a fine balance of metabolism that includes both anabolic and catabolic activities. Therefore, the biology of chondrocytes is critical for understanding ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6a5f04e511ae8cd8a87f221ed11058
https://doi.org/10.1002/jcp.21994
https://doi.org/10.1002/jcp.21994
Autor:
Ruth J. Mayer, Linda C. Warnock, Dave Singh, Stewart Bates, Ruth Tal-Singer, Joanna Betts, Christopher Larminie, Chris Clayton, Bryan E. Hoffman
Publikováno v:
Pharmacology Research & Perspectives
The p38 mitogen-activated protein kinase (MAPK) intracellular signaling pathway responds to a variety of extracellular stimuli, including cytokines, Toll-like receptor agonists, and components of cigarette smoke to influence the expression of proinfl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378fe8750a892a701dd48bc68af865c4
https://doi.org/10.1002/prp2.94
https://doi.org/10.1002/prp2.94
RNA aptamers selected against proteins can be used to modulate specific protein function. Expression of such reagents in cells and whole organisms could provide a means of dissecting and controlling molecular mechanisms in vivo . We demonstrate that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54db330556bee4e6b17f1909e418689
https://europepmc.org/articles/PMC17837/
https://europepmc.org/articles/PMC17837/
Autor:
William N. Bell, Antony Chadderton, Connie L. Erickson-Miller, David P. Steensma, Joanne J. Lager, Kevin H. Laubscher, Julie C. Porcher, Deb Jaworski, Bryan E. Hoffman
Publikováno v:
Blood. 110:3661-3661
Background: Many patients (pts) with anemia due to impaired erythropoiesis fail to respond to currently available erythropoiesis-stimulating agents or do not wish to receive these agents due to safety concerns. For these pts, novel approaches are nee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58d2c8a5b3e2d335d3b250a3df53d528
https://doi.org/10.1182/blood.v110.11.3661.3661
https://doi.org/10.1182/blood.v110.11.3661.3661