Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bryan Dickinson"'
Publikováno v:
Hum Mol Genet
RNA modifications affect many aspects of RNA metabolism and are involved in the regulation of many different biological processes. Mono-methylation of adenosine in the N1 position, N1-methyladensoine (m1A), is a reversible modification that is known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37e34705b65fb82ddda781975f80001
https://doi.org/10.1093/hmg/ddab357
https://doi.org/10.1093/hmg/ddab357
Development of an improved reporter system for assessing the activity of programmable RNA regulators
RNA-binding proteins (RBPs) play a key role in the control of gene expression through their regulation of mRNA half-life, localization, chemical composition, and translation. Aside from their roles in native biological regulation, RBP functions can a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dac70f2cf6e8a5caeca428ddf3a344a
https://doi.org/10.26434/chemrxiv-2022-6qv3b
https://doi.org/10.26434/chemrxiv-2022-6qv3b
Molecules that induce interactions between proteins, often referred to as “molecular glues”, are increasingly recognized as important therapeutic modalities and as entry points for rewiring cellular signaling networks. Here, we report a new PACE-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cd6433a9afcf52558e1b085503f46ef
https://doi.org/10.26434/chemrxiv-2021-ss23c
https://doi.org/10.26434/chemrxiv-2021-ss23c
Protein S-acylation is a dynamic lipid post-translational modification that can modulate the localization and activity of target proteins. In humans, the installation of the lipid onto target proteins is catalyzed by a family of 23 Asp-His-His-Cys do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a25f4b26e8416d3fc37e47031710105
https://doi.org/10.26434/chemrxiv.13755763.v1
https://doi.org/10.26434/chemrxiv.13755763.v1
RNA regulation is critical for gene expression control, but tools to temporally manipulate RNA regulatory mechanisms are lacking. Here, we present small molecule-inducible RNA-targeting effectors based on our previously developed CRISPR/Cas-inspired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc6f52832b1f961a586849469b6ef8d
https://doi.org/10.26434/chemrxiv.11673711.v2
https://doi.org/10.26434/chemrxiv.11673711.v2
Autor:
Krysten A. Jones, Kaitlin Kentala, Michael Beck, Weiwei An, Alexander Lippert, Jared C. Lewis, Bryan Dickinson
Split reporters based on fluorescent proteins and luciferases have emerged as valuable tools for measuring interactions in biological systems. Relatedly, biosensors that transduce measured input signals into outputs that influence the host system are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26c0f834bc76d07c478a638b2ddcd44d
https://doi.org/10.26434/chemrxiv.8258633.v1
https://doi.org/10.26434/chemrxiv.8258633.v1
Autor:
Krysten A. Jones, Kaitlin Kentala, Michael Beck, Weiwei An, Alexander Lippert, Jared C. Lewis, Bryan Dickinson
Split reporters based on fluorescent proteins and luciferases have emerged as valuable tools for measuring interactions in biological systems. Relatedly, biosensors that transduce measured input signals into outputs that influence the host system are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b6c71471b360ad907ede8022bf9d11
https://doi.org/10.26434/chemrxiv.8258633.v2
https://doi.org/10.26434/chemrxiv.8258633.v2