Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Bryan D. White"'
Publikováno v:
Gastroenterology. 142:219-232
Aberrant Wnt/β-catenin signaling is widely implicated in numerous malignancies, including cancers of the gastrointestinal tract. Dysregulation of signaling is traditionally attributed to mutations in Axin, adenomatous polyposis coli, and β-catenin
Autor:
Ryan J. Nathe, Randall T. Moon, Philip J. Horner, Jamie M. Goodson, Nghi K. Nguyen, Bryan D. White, Don O. Maris
Publikováno v:
Stem Cells. 28:297-307
Wnt/β-catenin signaling can influence the proliferation and differentiation of progenitor populations in the hippocampus and subventricular zone, known germinal centers in the adult mouse brain. It is not known whether β-catenin signaling occurs in
Autor:
Xin Zheng, Abdelhadi Rebbaa, Bernard L. Mirkin, Marianne E. Greene, Bryan D. White, Fei Chu, Sandra H. Clark
Publikováno v:
Oncogene. 24:4965-4974
Resistance to cytotoxic agents is a major limitation for their clinical use to treat human cancers. Tumors become resistant to chemotherapy when a subset of cells undergoes molecular changes leading to overexpression of drug transport proteins, alter
Autor:
BRYAN D. WHITE, NATHE, RYAN J., MARIS4, DON O., NGUYEN, NGHI K., GOODSON, JAMIE M., MOON, RANDALL T., HORNER, PHILIP J.
Publikováno v:
Stem Cells; Feb2010, Vol. 28 Issue 2, p297-307, 11p, 1 Color Photograph, 6 Graphs
Autor:
Daniel M. Fass, Jeanot Muster, Erin C. Moore, Stephen J. Haggarty, Corinne M. Taraska, Rakesh Karmacharya, Nicholas C. Robin, Rima M. Kulikauskas, Bryan D. White, Randall T. Moon, Nathan D. Camp, Andy J. Chien, Travis L. Biechele
Publikováno v:
Chemistry & Biology. (11):1177-1182
SummaryTo identify new protein and pharmacological regulators of Wnt/β-catenin signaling, we used a cell-based reporter assay to screen a collection of 1857 human-experienced compounds for their ability to enhance activation of the β-catenin report
Publikováno v:
Current Biology. (21):R923-R925
Summary In addition to its myriad of contributions in development, disease and regeneration, recent research implicates the Wnt/β-catenin signaling cascade in yet another biological process — aging. The latest role of Wnt uncovers new complexities