Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Bryan D. Schindler"'
Autor:
Ivan Birukou, Nam K. Tonthat, Susan M. Seo, Bryan D. Schindler, Glenn W. Kaatz, Richard G. Brennan
Publikováno v:
mBio, Vol 4, Iss 5 (2013)
ABSTRACT Overexpression of the Staphylococcus aureus multidrug efflux pump MepA confers resistance to a wide variety of antimicrobials. mepA expression is controlled by MarR family member MepR, which represses mepA and autorepresses its own productio
Externí odkaz:
https://doaj.org/article/07f73ecbe7c84e91b1c2658cca5f9fe4
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
The metal-reducing bacterium Geobacter sulfurreducens requires the expression of conductive pili to reduce iron oxides and to wire electroactive biofilms, but the role of pilus retraction in these functions has remained elusive. Here we show that of
Externí odkaz:
https://doaj.org/article/b96c7242c81a4d2fbe4dbd780108d1af
Autor:
Rolando Cannalire, Maria Letizia Barreca, Tommaso Felicetti, Maria Sole Burali, Bryan D. Schindler, Serena Massari, Glenn W. Kaatz, Giuseppe Manfroni, Violetta Cecchetti, Oriana Tabarrini, Stefano Sabatini
Publikováno v:
ChemMedChem. 12:1293-1302
Bacterial resistance to antimicrobial agents has become an increasingly serious health problem in recent years. Among the strategies by which resistance can be achieved, overexpression of efflux pumps such as NorA of Staphylococcus aureus leads to a
Autor:
Bryan D. Schindler, Gabriele Cruciani, Glenn W. Kaatz, Federica Buonerba, Susan Lepri, Renzo Ruzziconi, Irene Velilla, Susan M. Seo, Laura Goracci
Publikováno v:
Journal of Medicinal Chemistry. 59:867-891
Antibiotic resistance represents a worldwide concern, especially regarding the outbreak of methicillin-resistant Staphylococcus aureus, a common cause for serious skin and soft tissues infections. A major contributor to Staphylococcus aureus antibiot
Autor:
Stefano Sabatini, Oriana Tabarrini, Maria Letizia Barreca, Bryan D. Schindler, Giuseppe Manfroni, Violetta Cecchetti, Tommaso Felicetti, Rolando Cannalire, Maria Giulia Nizi, Serena Massari, Glenn W. Kaatz
The alarming and rapid spread of antimicrobial resistance among bacteria represents a high risk for global health. Targeting factors involved in resistance to restore the activity of failing antibiotics is a promising strategy to overcome this urgent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f531242372d87d60a55957097f577f9b
http://hdl.handle.net/11391/1438113
http://hdl.handle.net/11391/1438113
Autor:
Oriana Tabarrini, Maria Letizia Barreca, Bryan D. Schindler, Serena Massari, Glenn W. Kaatz, Gniewomir Latacz, Giuseppe Manfroni, Tommaso Felicetti, Violetta Cecchetti, Katarzyna Kieć-Kononowicz, Donatella Pietrella, Stefano Sabatini, Rolando Cannalire, Annamaria Lubelska
Antimicrobial resistance (AMR) represents a hot topic in drug discovery. Besides the identification of new antibiotics, the use of nonantibiotic molecules to block resistance mechanisms is a powerful alternative. Bacterial efflux pumps exert an early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9e1b872ca0db46662d5aac5d588410
https://ruj.uj.edu.pl/xmlui/handle/item/107693
https://ruj.uj.edu.pl/xmlui/handle/item/107693
Publikováno v:
Journal of Bacteriology. 197:1104-1114
The expression of mepA , encoding the Staphylococcus aureus MepA multidrug efflux protein, is repressed by the MarR homologue MepR. Repression occurs through binding of two MepR dimers to an operator with two homologous and closely approximated pseud
Autor:
Glenn W. Kaatz, Bryan D. Schindler, Susan Lepri, Laura Goracci, Gabriele Cruciani, Susan M. Seo, Federica Buonerba
The NorA efflux pump is a potential drug target for reversal of resistance to selected antibacterial agents, and recently we described indole-based inhibitor candidates. Herein we report a second class of inhibitors derived from them but with signifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47abe5ff38bf3b14864ef2420615d87
http://hdl.handle.net/11391/1398662
http://hdl.handle.net/11391/1398662
Publikováno v:
Antimicrobial Drug Resistance ISBN: 9783319467160
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bd353a84a07b00351d63e3b44e49051
https://doi.org/10.1007/978-3-319-46718-4_16
https://doi.org/10.1007/978-3-319-46718-4_16
Autor:
Jonathan Curry, Winnie Ka Po Shiu, Shazad Mushtaq, Marina Warner, Stephen Neidle, Simon Gibbons, David M. Livermore, Susan M. Seo, David L. Coleman, Bryan D. Schindler, Dimitrios Evangelopoulos, Chandrakala Basavannacharya, Glenn W. Kaatz, John P. Malkinson, Sanjib Bhakta, Paul Stapleton, M. Mukhlesur Rahman, Mekala Gunaratnam
Publikováno v:
International Journal of Antimicrobial Agents. 42:513-518
An in-depth evaluation was undertaken of a new antibacterial natural product (1) recently isolated and characterised from the plant Hypericum olympicum L. cf. uniflorum. Minimum inhibitory concentrations (MICs) were determined for a panel of bacteria