Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bryan D. Mets"'
Autor:
Anna K. Kopec, Lyle D. Burgoon, Jack R. Harkema, Bonnie Sharratt, Timothy R. Zacharewski, Colleen Tashiro, Bryan D. Mets, Dave Potter, Daher Ibrahim-Aibo
Publikováno v:
Toxicology and Applied Pharmacology. 243:359-371
Polychlorinated biphenyls (PCBs) are ubiquitous contaminants found as complex mixtures of coplanar and non-coplanar congeners. The hepatic temporal and dose-dependent effects of the most abundant non-dioxin-like congener, 2,2',4,4',5,5'-hexachlorobip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016e74aeed42746e4f9374991eb2c617
https://doi.org/10.1016/j.taap.2009.12.003
https://doi.org/10.1016/j.taap.2009.12.003
Autor:
Sandra O'Reilly, Piro Lito, J. Justin McCormick, Bryan D. Mets, Veronica M. Maher, Susanne Kleff
Publikováno v:
Journal of Biological Chemistry. 283:2002-2009
Sprouty 2 (Spry2) acts as an inhibitor of receptor tyrosine kinase signaling in various cellular contexts. Interestingly, Spry2 also prevents the c-Cbl-induced degradation of epidermal growth factor receptor (EGFR). We compared human fibroblasts mali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b41fedb61f9f1b77c0f0584e3f16c6
https://doi.org/10.1074/jbc.m709046200
https://doi.org/10.1074/jbc.m709046200
Autor:
Agnes L. Forgacs, Meghan K. Makley, Nicholas V. Reo, Nicholas J. DelRaso, Gary L. Jahns, Michael N. Kent, Lyle D. Burgoon, Timothy R. Zacharewski, Bryan D. Mets
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a persistent environmental contaminant that elicits a broad spectrum of biochemical and toxic effects in a species-specific manner. These effects include hepatotoxicity, immunotoxicity, endocrine disrupti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c129f5dd4f2b61b4c43acfafcb032f8
https://europepmc.org/articles/PMC3243745/
https://europepmc.org/articles/PMC3243745/
Autor:
Bonnie Sharratt, Colleen Tashiro, Bryan D. Mets, Lyle D. Burgoon, Timothy R. Zacharewski, Kellie J. Archer, Anna K. Kopec, Dave Potter, Michelle L. D’Souza, Sarah E. Reese, Jack R. Harkema
Interactions between environmental contaminants can lead to non-additive effects that may affect the toxicity and risk assessment of a mixture. Comprehensive time course and dose-response studies with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), non-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485a8d417409d799b8f5864e724aec82
https://europepmc.org/articles/PMC4126514/
https://europepmc.org/articles/PMC4126514/
We have reported that expression of Sprouty 2 (Spry2) is necessary for tumor formation by HRasV12-transformed fibroblasts. We now report on the role of Spry2 in the inhibition of UV254 nm radiation-induced apoptosis in HRasV12-transformed human fibro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae378b1b22bce83dad67a287be99a0f
https://europepmc.org/articles/PMC2613613/
https://europepmc.org/articles/PMC2613613/