Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Bryan D Choi"'
Autor:
Irene Scarfò, Marcela V Maus, Andrea Schmidts, Leah C Marsh, Ambike A Srivastava, Amanda A Bouffard, Angela C Boroughs, Rebecca C Larson, Felipe Bedoya, Bryan D Choi, Matthew J Frigault, Stefanie R Bailey, Mark B Leick, Sonika Vatsa, Michael C Kann, Michelle S Prew, Benjamin P Kleinstiver, J Keith Joung
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Adoptive cell therapy with chimeric antigen receptor T cells (CAR-T) has become a standard treatment for patients with certain aggressive B cell malignancies and holds promise to improve the care of patients suffering from numerous other c
Externí odkaz:
https://doaj.org/article/1383b25b9a8e4f49a0640c17e9556951
Autor:
Hongsheng Miao, Bryan D Choi, Carter M Suryadevara, Luis Sanchez-Perez, Shicheng Yang, Gabriel De Leon, Elias J Sayour, Roger McLendon, James E Herndon, Patrick Healy, Gary E Archer, Darell D Bigner, Laura A Johnson, John H Sampson
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94281 (2014)
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults and is uniformly lethal. T-cell-based immunotherapy offers a promising platform for treatment given its potential to specifically target tumor tissue while sparing the norm
Externí odkaz:
https://doaj.org/article/d47e7819adf54a82a2ea64097678daa4
Autor:
Luis A Sanchez-Perez, Bryan D Choi, Gary E Archer, Xiuyu Cui, Catherine Flores, Laura A Johnson, Robert J Schmittling, David Snyder, James E Herndon, Darell D Bigner, Duane A Mitchell, John H Sampson
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59082 (2013)
Temozolomide (TMZ) is an alkylating agent shown to prolong survival in patients with high grade glioma and is routinely used to treat melanoma brain metastases. A prominent side effect of TMZ is induction of profound lymphopenia, which some suggest m
Externí odkaz:
https://doaj.org/article/35e9b35443d2484fa4d782fdea9099f5
Autor:
Gust Vandecandelaere, Rishab Ramapriyan, Matthew Gaffey, Leland Geoffrey Richardson, Samuel Jeffrey Steuart, Masih Tazhibi, Adrian Kalaw, Eric P. Grewal, Jing Sun, William T. Curry, Bryan D. Choi
Publikováno v:
Cells, Vol 13, Iss 17, p 1480 (2024)
Immunotherapy represents a transformative shift in cancer treatment. Among myriad immune-based approaches, chimeric antigen receptor (CAR) T-cell therapy has shown promising results in treating hematological malignancies. Despite aggressive treatment
Externí odkaz:
https://doaj.org/article/868cd5c799464249a0cfb3e80f9d4e04
Publikováno v:
Tomography, Vol 9, Iss 1, Pp 274-284 (2023)
While the advent of immunotherapy has revolutionized cancer treatment, its use in the treatment of glioblastoma (GBM) has been less successful. Most studies using immunotherapy in GBM have been negative and the reasons for this are still being studie
Externí odkaz:
https://doaj.org/article/223cea8ac64e40a3bd29bb06dec74439
Autor:
Rishab Ramapriyan, Jing Sun, Annabel Curry, Leland G. Richardson, Tarun Ramesh, Matthew A. Gaffey, Patrick C. Gedeon, Elizabeth R. Gerstner, William T. Curry, Bryan D. Choi
Publikováno v:
Antibodies, Vol 12, Iss 4, p 74 (2023)
This review explores the evolving landscape of antibody-based therapies in neuro-oncology, in particular, immune checkpoint inhibitors and immunomodulatory antibodies. We discuss their mechanisms of action, blood-brain barrier (BBB) penetration, and
Externí odkaz:
https://doaj.org/article/5ff1171fc4b74dadbda7953a870d9548
Autor:
Andrea Schmidts, Maria Ormhøj, Bryan D. Choi, Allison O. Taylor, Amanda A. Bouffard, Irene Scarfò, Rebecca C. Larson, Matthew J. Frigault, Kathleen Gallagher, Ana P. Castano, Lauren S. Riley, Maria L. Cabral, Angela C. Boroughs, Rubí M.-H. Velasco Cárdenas, Wolfgang Schamel, Jing Zhou, Sean Mackay, Yu-Tzu Tai, Kenneth C. Anderson, Marcela V. Maus
Publikováno v:
Blood Advances, Vol 3, Iss 21, Pp 3248-3260 (2019)
Abstract: Chimeric antigen receptor (CAR) T cells (CARTs) have shown tremendous potential for the treatment of certain B-cell malignancies, including patients with relapsed/refractory multiple myeloma (MM). Targeting the B-cell maturation antigen (BC
Externí odkaz:
https://doaj.org/article/744190eefb7f4eac95dde4520a55224b
Autor:
Marcela V. Maus, Matthew J. Frigault, Torben Barington, David M. Weinstock, Henrik J. Ditzel, Morten F. Gjerstorff, Jacob H. Christensen, Charlotte G. Nyvold, Oriane Cédile, Rikke S. Andersen, Bryan D. Choi, Andrea Schmidts, Lauren S. Riley, Rebecca C. Larson, Ana P. Castano, Amanda A. Bouffard, Selena J. Lorrey, Stefanie R. Bailey, Maria L. Cabral, Irene Scarfò, Maria Ormhøj
Supplementary Materials and Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4582e5857ca892ad3132a1732e1514a3
https://doi.org/10.1158/1078-0432.22471292.v1
https://doi.org/10.1158/1078-0432.22471292.v1
Related Article from Regulatory T Cells Move in When Gliomas Say “I DO”
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f2b473f44a35f7e4b57a383fb0373a
https://doi.org/10.1158/1078-0432.22447650
https://doi.org/10.1158/1078-0432.22447650
Autor:
John H. Sampson, Darell D. Bigner, Luis Sanchez-Perez, Elizabeth A. Reap, Gary E. Archer, Stephen T. Keir, Roger E. McLendon, James E. Herndon, Patrick N. Healy, Xiuyu Cui, Scott E. Szafranski, Robert J. Schmittling, David J. Snyder, Carter M. Suryadevara, Chien-Tsun Kuan, Bryan D. Choi, Satish K. Chitneni, Teilo H. Schaller, Patrick C. Gedeon
Table S2 - Glioma cell lines and patient derived tumor samples used for study with the number of EGFRvIII receptors per cell, the number of EGFRwt receptors per cell and the proportion of cells expressing EGFRvIII in the given cell line or tumor samp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044ccc0bbab6f20d0b58d82dddba22dd
https://doi.org/10.1158/1078-0432.22464450.v1
https://doi.org/10.1158/1078-0432.22464450.v1