Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bryan C. Hall"'
Autor:
Matthew T. Duggan, Melissa F. Groleau, Ethan P. Shealy, Lillian S. Self, Taylor E. Utter, Matthew M. Waller, Bryan C. Hall, Chris G. Stone, Layne L. Anderson, Timothy A. Mousseau
Publikováno v:
Ecology and Evolution, Vol 11, Iss 17, Pp 12051-12063 (2021)
Abstract Camera traps have become an extensively utilized tool in ecological research, but the manual processing of images created by a network of camera traps rapidly becomes an overwhelming task, even for small camera trap studies. We used transfer
Externí odkaz:
https://doaj.org/article/b9611a39a70546e8b6259cd0762b3a3c
Autor:
Theresa M. Reineke, Zachary P. Tolstyka, Bryan C. Hall, Joseph K. Hexum, Perry B. Hackett, Haley R. Phillips
Publikováno v:
Biomacromolecules. 20:1530-1544
Genome editing therapies hold great promise for the cure of monogenic and other diseases; however, the application of nonviral gene delivery methods is limited by both a lack of fundamental knowledge of interactions of the gene-carrier in complex ani
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78161 (2013)
The Sleeping Beauty transposon system, a non-viral, integrating vector that can deliver the alpha-L-iduronidase-encoding gene, is efficient in correcting mucopolysaccharidosis type I in NOD/SCID mice. However, in previous studies we failed to attain
Externí odkaz:
https://doaj.org/article/74230a94deee433a9d3f7d99c71736f8
Autor:
Elena L. Aronovich, Myra Rusten, Jason B. Bell, Bryan C. Hall, David W. Hunter, N. Matthew Ellinwood, R. Scott McIvor, Erik R. Olson, Perry B. Hackett, Kendra A. Hyland
Publikováno v:
Human gene therapy. 28(7)
The non-viral, integrating Sleeping Beauty (SB) transposon system is efficient in treating systemic monogenic disease in mice, including hemophilia A and B caused by deficiency of blood clotting factors and mucopolysaccharidosis types I and VII cause
Autor:
Perry B. Hackett, Yogesh K. Dhande, Theresa M. Reineke, Bharat Wagh, Dustin Sprouse, Bryan C. Hall
Publikováno v:
Biomacromolecules. 17(3)
The liver is an ideal target for nucleic acid therapeutic applications (i.e., siRNA, gene therapy, and genome editing) due to its ability to secrete proteins into the blood. In this work, we present the first synthesis of a novel monomer derived from
Autor:
R. Scott McIvor, Elena L. Aronovich, Myra Rusten, Chester B. Whitley, Kendra A. Hyland, David W. Hunter, Perry B. Hackett, Erik R. Olson, Jason B. Bell, N. Matthew Ellinwood, Bryan C. Hall
Publikováno v:
Molecular Therapy. 24:S174
The non-viral integrating vector the Sleeping Beauty (SB) transposon system is efficient in treating systemic monogenic diseases in mice including mucopolysaccharidosis (MPS) types I and VII caused by α-iduronidase (IDUA) and β-glucuronidase (GUSB)
Publikováno v:
Molecular Genetics and Metabolism. 114:S50
CO RR EC TE D P RO OF transposon system for gene therapy of both MPS I and MPS VII in adult mice. Although more than 99% of transgene expression comes from the liver following hydrodynamic delivery, restoration of deficient enzyme activity in other o
Publikováno v:
Molecular Genetics and Metabolism. 108:S46
Publikováno v:
Molecular Genetics and Metabolism. 108:S20
treatment. Onset of neurological symptoms at age 8 and in adolescence. Pair 4: L.M. died at age 5 months due to liver failure. P.M. (7 years): earlyinfantile form, despite treatment start at age 2 progressive neurological deterioration. Pair 5: R.K.: