Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Bryan C Pascual"'
Autor:
Gary KL Chan, Samantha Maisel, Yeonjoo C Hwang, Bryan C Pascual, Rebecca RB Wolber, Phuong Vu, Krushna C Patra, Mehdi Bouhaddou, Heidi L Kenerson, Huat C Lim, Donald Long, Raymond S Yeung, Praveen Sethupathy, Danielle L Swaney, Nevan J Krogan, Rigney E Turnham, Kimberly J Riehle, John D Scott, Nabeel Bardeesy, John D Gordan
Publikováno v:
eLife, Vol 12 (2023)
Genetic alterations that activate protein kinase A (PKA) are found in many tumor types. Yet, their downstream oncogenic signaling mechanisms are poorly understood. We used global phosphoproteomics and kinase activity profiling to map conserved signal
Externí odkaz:
https://doaj.org/article/05fc37cffa674796bf7877b4353fc32a
Autor:
Sophia M. Lauer, Mitchell H. Omar, Martin G. Golkowski, Heidi L. Kenerson, Kyung-Soon Lee, Bryan C. Pascual, Huat C. Lim, Katherine Forbush, F. Donelson Smith, John D. Gordan, Shao-En Ong, Raymond S. Yeung, John D. Scott
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113678- (2024)
Summary: The DNAJ-PKAc fusion kinase is a defining feature of fibrolamellar carcinoma (FLC). FLC tumors are notoriously resistant to standard chemotherapies, with aberrant kinase activity assumed to be a contributing factor. By combining proximity pr
Externí odkaz:
https://doaj.org/article/0017dacb347145b2ba79f18c4ba57c47
Autor:
Gary KL Chan, Samantha Maisel, Yeonjoo C Hwang, Bryan C Pascual, Rebecca RB Wolber, Phuong Vu, Krushna C Patra, Mehdi Bouhaddou, Heidi L Kenerson, Huat C Lim, Donald Long, Raymond S Yeung, Praveen Sethupathy, Danielle L Swaney, Nevan J Krogan, Rigney E Turnham, Kimberly J Riehle, John D Scott, Nabeel Bardeesy, John D Gordan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e57702eaa8f41296e52fffc2f1b15a79
https://doi.org/10.7554/elife.69521.sa2
https://doi.org/10.7554/elife.69521.sa2
