Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Bryan C Au"'
Autor:
Ju Huang, Yuanfeng Liu, Bryan C Au, Dwayne L Barber, Andrea Arruda, Axel Schambach, Michael Rothe, Mark D Minden, Christopher J Paige, Jeffrey A Medin
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Interleukin-12 (IL-12) is a potent cytokine that may be harnessed to treat cancer. To date, nearly 100 IL-12-based clinical trials have been initiated worldwide. Yet systemic administration of IL-12 is toxic. Different strategies are being developed
Externí odkaz:
https://doaj.org/article/57606d1514384bb1a972cad69db16119
Autor:
Ju, Huang, Aneal, Khan, Bryan C, Au, Dwayne L, Barber, Lucía, López-Vásquez, Nicole L, Prokopishyn, Michel, Boutin, Michael, Rothe, Jack W, Rip, Mona, Abaoui, Murtaza S, Nagree, Shaalee, Dworski, Axel, Schambach, Armand, Keating, Michael L, West, John, Klassen, Patricia V, Turner, Sandra, Sirrs, C Anthony, Rupar, Christiane, Auray-Blais, Ronan, Foley, Jeffrey A, Medin
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Fabry disease is a rare lysosomal storage disorder (LSD). We designed multiple recombinant lentivirus vectors (LVs) and tested their ability to engineer expression of human α-galactosidase A (α-gal A) in transduced Fabry patient CD34+ hematopoietic
Autor:
Bryan C. Au, Chyan-Jang Lee, Orlay Lopez-Perez, Warren Foltz, Tania C. Felizardo, James C.M. Wang, Ju Huang, Xin Fan, Melissa Madden, Alyssa Goldstein, David A. Jaffray, Badru Moloo, J. Andrea McCart, Jeffrey A. Medin
Publikováno v:
Biomedicines, Vol 4, Iss 1, p 6 (2016)
Anti-cancer immunotherapy is emerging from a nadir and demonstrating tangible benefits to patients. A variety of approaches are now employed. We are invoking antigen (Ag)-specific responses through direct injections of recombinant lentivectors (LVs)
Externí odkaz:
https://doaj.org/article/15278be89cf84754884d92928168d3dc