Výsledky vyhledávání - "Bryan Bowser"

Author’s Response to 'A Letter in Support of Real-World RECIST'

Autor: Che-Hsu Joe Chang, Deborah Schrag, Rebecca A. Miksad, Geoffrey Calkins, Sean Khozin, Sandra D. Griffith, Josh Kraut, Paul You, Ellie Guardino, Melisa Tucker, Bryan Bowser

Publikováno v: Advances in Therapy. 37:1691-1693

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2163225c586fdfebf4c78d074bc6af9
https://doi.org/10.1007/s12325-020-01246-9

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Generating Real-World Tumor Burden Endpoints from Electronic Health Record Data: Comparison of RECIST, Radiology-Anchored, and Clinician-Anchored Approaches for Abstracting Real-World Progression in Non-Small Cell Lung Cancer

Autor: Bryan Bowser, Deborah Schrag, Che-Hsu Joe Chang, Rebecca A. Miksad, Geoffrey Calkins, Ellie Guardino, Sandra D. Griffith, Sean Khozin, Josh Kraut, Melisa Tucker, Paul You

Publikováno v: Advances in Therapy

Introduction Real-world evidence derived from electronic health records (EHRs) is increasingly recognized as a supplement to evidence generated from traditional clinical trials. In oncology, tumor-based Response Evaluation Criteria in Solid Tumors (R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be75e85f30ebcffdb10a85c20ac2a266
https://doi.org/10.1007/s12325-019-00970-1

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Characterization of a Real-World Response Variable and Comparison with RECIST-Based Response Rates from Clinical Trials in Advanced NSCLC

Autor: Joshua S. Kraut, Ariel Bulua Bourla, Xinran Ma, Nathan C. Nussbaum, Kelly Magee, Bryan Bowser, Lawrence Bellomo, Meghna Samant, Olga Tymejczyk, Caroline S. Bennette, Melisa Tucker

Publikováno v: Advances in Therapy

Introduction Effectiveness metrics for real-word research, analogous to clinical trial ones, are needed. This study aimed to develop a real-world response (rwR) variable applicable to solid tumors and to evaluate its clinical relevance and meaningful

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc6fa4a2e86cce17747af6f39646757
https://pubmed.ncbi.nlm.nih.gov/33674928

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Generating real-world tumor burden endpoints from electronic health record data: Comparison of RECIST, radiology-anchored, and clinician-anchored approaches for abstracting real-world progression in non-small cell lung cancer

Autor: Deborah Schrag, Rebecca A. Miksad, Che-Hsu Joe Chang, Ellie Guardino, Amy P. Abernethy, Josh Kraut, Paul You, Geoffrey Calkins, Sandra D. Griffith, Sean Khozin, Melissa Tucker, Bryan Bowser

Real-world evidence derived from electronic health records (EHRs) is increasingly recognized as a supplement to evidence generated from traditional clinical trials. In oncology, tumor-based Response Evaluation Criteria in Solid Tumors (RECIST) endpoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc7ad01c9f9f9aa3405558a6eee6dc3

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Association of Patient Characteristics and Tumor Genomics With Clinical Outcomes Among Patients With Non–Small Cell Lung Cancer Using a Clinicogenomic Database

Publikováno v: JAMA. 321:1391

Importance Data sets linking comprehensive genomic profiling (CGP) to clinical outcomes may accelerate precision medicine. Objective To assess whether a database that combines EHR-derived clinical data with CGP can identify and extend associations in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a71d839a782a7d3f41efb04388f2a467
https://doi.org/10.1001/jama.2019.3241

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Development and validation of a real-world clinicogenomic database

Publikováno v: Journal of Clinical Oncology. 35:2514-2514

2514 Background: Genomic findings have diagnostic, prognostic, and predictive utility in clinical oncology. Population studies have been limited by reliance on trials, registries, or institutional chart review, which are costly and represent narrow p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49597d8171bd5bd1d80376d3c4ba52ee
https://doi.org/10.1200/jco.2017.35.15_suppl.2514

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Contemporary management of advanced non-small cell lung cancer (aNSCLC) in a large, real-world cohort

Autor: Bryan Bowser, Eoghan Harrington, Roy S. Herbst, Vineeta Agarwala, Cary P. Gross, Kerin B. Adelson, Carolyn Jean Presley, James Gippetti, Amy P. Abernethy

Publikováno v: Journal of Clinical Oncology. 34:e20621-e20621

e20621Background: In the era of precision medicine for NSCLC, the use of tumor genotyping and novel therapies in routine clinical practice is unknown. Methods: Patient characteristics, genotype tes...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5cc17d6ec5660d0d11a2217d84f4196f
https://doi.org/10.1200/jco.2016.34.15_suppl.e20621

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