Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bryan Bollman"'
Autor:
In Young Choi, Laura Piccio, Patra Childress, Bryan Bollman, Arko Ghosh, Sebastian Brandhorst, Jorge Suarez, Andreas Michalsen, Anne H. Cross, Todd E. Morgan, Min Wei, Friedemann Paul, Markus Bock, Valter D. Longo
Publikováno v:
Cell Reports, Vol 15, Iss 10, Pp 2136-2146 (2016)
Dietary interventions have not been effective in the treatment of multiple sclerosis (MS). Here, we show that periodic 3-day cycles of a fasting mimicking diet (FMD) are effective in ameliorating demyelination and symptoms in a murine experimental au
Externí odkaz:
https://doaj.org/article/6c2cdc8b11ae4ecbb87f2c86c06b723b
Autor:
Fabia Filipello, Shih-Feng You, Farzaneh S. Mirfakhar, Sidhartha Mahali, Bryan Bollman, Mariana Acquarone, Olena Korvatska, Jacob A. Marsh, Anirudh Sivaraman, Rita Martinez, Claudia Cantoni, Luca De Feo, Laura Ghezzi, Miguel A. Minaya, Arun Renganathan, Anil G. Cashikar, Jun-Ichi Satoh, Wandy Beatty, Abhirami K. Iyer, Marina Cella, Wendy H. Raskind, Laura Piccio, Celeste M. Karch
Publikováno v:
Acta Neuropathologica. 145:749-772
TREM2 is an innate immune receptor expressed by microglia in the adult brain. Genetic variation in the TREM2 gene has been implicated in risk for Alzheimer’s disease and frontotemporal dementia, while homozygous TREM2 mutations cause a rare leukody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1808ffc92b74dc4bbdd42e0fae1c83a4
https://doi.org/10.1007/s00401-023-02568-y
https://doi.org/10.1007/s00401-023-02568-y
Autor:
Federica Esposito, Ana Maria Osiceanu, Melissa Sorosina, Linda Ottoboni, Bryan Bollman, Silvia Santoro, Barbara Bettegazzi, Andrea Zauli, Ferdinando Clarelli, Elisabetta Mascia, Andrea Calabria, Daniele Zacchetti, Ruggero Capra, Maurizio Ferrari, Paolo Provero, Dejan Lazarevic, Davide Cittaro, Paola Carrera, Nikolaos Patsopoulos, Daniela Toniolo, A Dessa Sadovnick, Gianvito Martino, Philip L. De Jager, Giancarlo Comi, Elia Stupka, Carles Vilariño-Güell, Laura Piccio, Filippo Martinelli Boneschi
Publikováno v:
Genes; Volume 13; Issue 12; Pages: 2392
While the role of common genetic variants in multiple sclerosis (MS) has been elucidated in large genome-wide association studies, the contribution of rare variants to the disease remains unclear. Herein, a whole-genome sequencing study in four affec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15901d8cafef06cb787e422ef5d9a23
Autor:
Laura Ghezzi, Bryan Bollman, Luca De Feo, Laura Piccio, Bruce D. Trapp, Robert E. Schmidt, Anne H. Cross
Publikováno v:
Laboratory Investigation. 103:100128
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4471c25fa333b43d17019dba8d4db088
https://doi.org/10.1016/j.labinv.2023.100128
https://doi.org/10.1016/j.labinv.2023.100128
Autor:
Sindhu Manivasagam, Jessica L. Williams, Lauren L. Vollmer, Bryan Bollman, Juliet M. Bartleson, Shenjian Ai, Gregory F. Wu, Robyn S. Klein
Publikováno v:
J Immunol
Type III IFNs (IFNLs) are newly discovered cytokines, acting at epithelial and other barriers, that exert immunomodulatory functions in addition to their primary roles in antiviral defense. In this study, we define a role for IFNLs in maintaining aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1033b96091f74a9962af452f06f3da
https://europepmc.org/articles/PMC9012116/
https://europepmc.org/articles/PMC9012116/
Autor:
Danilo Licastro, Melissa Manis, Bryan Bollman, Fabia Filipello, Michael E. Buckland, Laura Piccio, Carlos Cruchaga, David M. Holtzman, Kathie A. Mihindukulasuriya, Adiljan Ibrahim, Bruno A. Benitez, Francesca Cignarella, Robert Mikesell, Alberto Locca, Claudia Cantoni, Ilaria Tassi, Arnon Rosenthal, Oscar Harari, Li Deng, Tina Schwabe
Publikováno v:
Acta Neuropathologica
Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease of the central nervous system (CNS) triggered by autoimmune mechanisms. Microglia are critical for the clearance of myelin debris in areas of demyelination, a ke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8a1cc95c24ecd7fea243ab646032fc
http://europepmc.org/articles/PMC7498497
http://europepmc.org/articles/PMC7498497
Autor:
Marina Cella, L Ghezzi, Francesca Cignarella, Bryan Bollman, Anne H. Cross, Amber Salter, Daniela Galimberti, Laura Piccio, Claudia Cantoni
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England). 26(10)
Background: Multiple sclerosis (MS) is a central nervous system (CNS) autoimmune demyelinating disease. Its pathogenesis involves humoral and cellular immunity, with production of pro- and anti-inflammatory cytokines by T cells. Objective: To analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f380e92aeab4b8afaa0e21bc4aed74
https://pubmed.ncbi.nlm.nih.gov/31237799
https://pubmed.ncbi.nlm.nih.gov/31237799
Autor:
Robyn S. Klein, Bette K. DeMasters, Joel R. Garbow, Daniel K. Wilton, James R. Bowen, Charise Garber, Arnaud Frouin, Denise A. Dorsey, Jinsheng Yu, Kenneth L. Tyler, Douglas M. Durrant, Mehul S. Suthar, Kristen E. Funk, Beth Stevens, Carlos J. Perez-Torres, Robert E. Schmidt, Michael J. Vasek, John K. Robinson, Steven Mennerick, Bryan Bollman, Xiaoping Jiang, Allison Soung
Publikováno v:
Nature. 534:538-543
Over 50% of patients who survive neuroinvasive infection with West Nile virus (WNV) exhibit chronic cognitive sequelae1,2. Although thousands of cases of WNV-mediated memory dysfunction accrue annually3, the mechanisms responsible for these impairmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008c66d61992341d20085d6dc62de3be
https://doi.org/10.1038/nature18283
https://doi.org/10.1038/nature18283
Autor:
Jorge Suarez, Markus Bock, Bryan Bollman, Sebastian Brandhorst, Patra Childress, Anne H. Cross, In Young Choi, Min Wei, Valter D. Longo, Arko Ghosh, Andreas Michalsen, Todd E. Morgan, Laura Piccio, Friedemann Paul
Publikováno v:
Cell Reports, Vol 15, Iss 10, Pp 2136-2146 (2016)
Summary Dietary interventions have not been effective in the treatment of multiple sclerosis (MS). Here, we show that periodic 3-day cycles of a fasting mimicking diet (FMD) are effective in ameliorating demyelination and symptoms in a murine experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de41bb9b98881ca172837644ad66e69
https://doi.org/10.1016/j.celrep.2016.05.009
https://doi.org/10.1016/j.celrep.2016.05.009
Autor:
Katharine A. Walz, Anne H. Cross, Gregory F. Wu, Jessica Koenigsknecht-Talboo, Angela S. Archambault, Bryan Bollman, Soomin Shin, David M. Holtzman, Julia Sim
Publikováno v:
Journal of Neuroimmunology. 271:8-17
Apolipoprotein E (ApoE) functions as a ligand in receptor-mediated endocytosis of lipoprotein particles and has been demonstrated to play a role in antigen presentation. To explore the contribution of ApoE during autoimmune central nervous system (CN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f0180703c7954787155521809dc899
https://doi.org/10.1016/j.jneuroim.2014.03.010
https://doi.org/10.1016/j.jneuroim.2014.03.010