Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Bryan Krastins"'
Autor:
Mary F. Lopez, Ping Niu, Lu Wang, Maryann Vogelsang, Meenakshi Gaur, Bryan Krastins, Yueqiang Zhao, Aibek Smagul, Aliya Nussupbekova, Aikan A. Akanov, I. King Jordan, Victoria V. Lunyak
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 3, Iss 1, Pp 1-15 (2017)
Stem cells aging: balancing self-renewal halt with complexity Mounting evidence suggests a link between cellular senescence and human adult stem cell function upon aging. Senescence is often viewed as an intrinsic program to prevent oncogenic transfo
Externí odkaz:
https://doaj.org/article/e3010ed26bd14b8ca45b854bb7cfd1b4
Autor:
Makoto Ohashi, Amy M Holthaus, Michael A Calderwood, Chiou-Yan Lai, Bryan Krastins, David Sarracino, Eric Johannsen
Publikováno v:
PLoS Pathogens, Vol 11, Iss 4, p e1004822 (2015)
The Epstein-Barr virus (EBV) nuclear proteins EBNA3A, EBNA3B, and EBNA3C interact with the cell DNA binding protein RBPJ and regulate cell and viral genes. Repression of the CDKN2A tumor suppressor gene products p16(INK4A) and p14(ARF) by EBNA3A and
Externí odkaz:
https://doaj.org/article/b69c37a2099e473a87d07172c07d4dd5
Autor:
Paul E Oran, Olgica Trenchevska, Dobrin Nedelkov, Chad R Borges, Matthew R Schaab, Douglas S Rehder, Jason W Jarvis, Nisha D Sherma, Luhui Shen, Bryan Krastins, Dawn C Schwenke, Peter D Reaven, Randall W Nelson
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92801 (2014)
Insulin-like growth factor 1 (IGF1) is an important biomarker for the management of growth hormone disorders. Recently there has been rising interest in deploying mass spectrometric (MS) methods of detection for measuring IGF1. However, widespread cl
Externí odkaz:
https://doaj.org/article/bb85b97f782f4818917849d3347eec55
Autor:
Eric E Niederkofler, David A Phillips, Bryan Krastins, Vathany Kulasingam, Urban A Kiernan, Kemmons A Tubbs, Scott M Peterman, Amol Prakash, Eleftherios P Diamandis, Mary F Lopez, Dobrin Nedelkov
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81125 (2013)
Insulin-like growth factor 1 (IGF1) is an important biomarker of human growth disorders that is routinely analyzed in clinical laboratories. Mass spectrometry-based workflows offer a viable alternative to standard IGF1 immunoassays, which utilize var
Externí odkaz:
https://doaj.org/article/23c14967bec94eddb24220f0f7f531c7
Autor:
Alaullah Sheikh, Farhana Khanam, Md Abu Sayeed, Taibur Rahman, Marcin Pacek, Yanhui Hu, Andrea Rollins, Md Saruar Bhuiyan, Sean Rollins, Anuj Kalsy, Mohammad Arifuzzaman, Daniel T Leung, David A Sarracino, Bryan Krastins, Richelle C Charles, Regina C Larocque, Alejandro Cravioto, Stephen B Calderwood, W Abdullah Brooks, Jason B Harris, Joshua Labaer, Firdausi Qadri, Edward T Ryan
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 6, p e1193 (2011)
Salmonella enterica serotype Typhi is a human-restricted intracellular pathogen and the cause of typhoid fever. Cellular immune responses are required to control and clear Salmonella infection. Despite this, there are limited data on cellular immune
Externí odkaz:
https://doaj.org/article/2a79d07a6ec9406c813033ac245c67f9
Autor:
Alejandra Garces, Krishnamohan Atmakuri, Michael R Chase, Joshua S Woodworth, Bryan Krastins, Alissa C Rothchild, Talia L Ramsdell, Mary F Lopez, Samuel M Behar, David A Sarracino, Sarah M Fortune
Publikováno v:
PLoS Pathogens, Vol 6, Iss 6, p e1000957 (2010)
Mycobacterium tuberculosis (Mtb) requires the ESX1 specialized protein secretion system for virulence, for triggering cytosolic immune surveillance pathways, and for priming an optimal CD8+ T cell response. This suggests that ESX1 might act primarily
Externí odkaz:
https://doaj.org/article/3c82ff02706441dd92e9f52dda4a3d32
Autor:
Amir H Qureshi, Vineet Chaoji, Dony Maiguel, Mohd Hafeez Faridi, Constantinos J Barth, Saeed M Salem, Mudita Singhal, Darren Stoub, Bryan Krastins, Mitsunori Ogihara, Mohammed J Zaki, Vineet Gupta
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7627 (2009)
During atherogenesis and vascular inflammation quiescent platelets are activated to increase the surface expression and ligand affinity of the integrin alphaIIbbeta3 via inside-out signaling. Diverse signals such as thrombin, ADP and epinephrine tran
Externí odkaz:
https://doaj.org/article/662aa7611cca4803aa05925336fc84ff
Autor:
Richelle C Charles, Jason B Harris, Michael R Chase, Lauren M Lebrun, Alaullah Sheikh, Regina C LaRocque, Tanya Logvinenko, Sean M Rollins, Abdullah Tarique, Elizabeth L Hohmann, Ian Rosenberg, Bryan Krastins, David A Sarracino, Firdausi Qadri, Stephen B Calderwood, Edward T Ryan
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e6994 (2009)
BACKGROUND:S. Typhi, a human-restricted Salmonella enterica serovar, causes a systemic intracellular infection in humans (typhoid fever). In comparison, S. Typhimurium causes gastroenteritis in humans, but causes a systemic typhoidal illness in mice.
Externí odkaz:
https://doaj.org/article/f8eb8ec01b4548b59bd1e0c614d5625e
Autor:
Peter Angelos, Edwin L. Kaplan, David A. Sarracino, Raymon H. Grogan, Bryan Krastins, Edward Ki Yun Leung, Christine C. Lee, Kiang-Teck J. Yeo, Mary F. Lopez, Theodore Karrison
Publikováno v:
The journal of applied laboratory medicine. 3(5)
Background We compared the rates of intraoperative parathyroid hormone (PTH) decline using the Siemens Immulite® Turbo PTH and Roche Elecsys® short turnaround time PTH assays in 95 consecutive surgical patients to investigate analytical and turnaro
Autor:
Jack Greenblatt, Zhen Yuan Lin, Harshika Jain, Ashley Hutchinson, Bryan Krastins, Mani Ravichandran, Anandi Bhattacharya, Lei Zhao, Alma Seitova, Tin Nguyen, Susanne Gräslund, Marcin Paduch, Anne-Claude Gingras, Gregory Byram, Cheryl H. Arrowsmith, Jeffrey R. Whiteaker, Ruedi Aebersold, Xinghua Guo, Maryann Vogelsang, Evan Dowdell, Aled M. Edwards, Ben C. Collins, Peter Loppnau, Gouri Vadali, Andrew Emili, Sadhna Phanse, Shuye Pu, Nan Zhong, Matthias Gstaiger, Hongbo Guo, Sachdev S. Sidhu, Amanda G. Paulovich, Brett Larsen, Lori Frappier, Jonathan B. Olsen, Shohei Koide, Edyta Marcon, Maria Fenner, Guoqing Zhong, Shane Miersch, Mary F. Lopez, Shoshana J. Wodak, Anthony A. Kossiakoff, Jacob J. Kennedy
Publikováno v:
Nature Methods. 12:725-731
Antibodies are used in multiple cell biology applications, but there are no standardized methods to assess antibody quality-an absence that risks data integrity and reproducibility. We describe a mass spectrometry-based standard operating procedure f