Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Bryan, Ulrich"'
Autor:
Xi Jiang, Chao Hu, Kyle Ferchen, Ji Nie, Xiaolong Cui, Chih-Hong Chen, Liting Cheng, Zhixiang Zuo, William Seibel, Chunjiang He, Yixuan Tang, Jennifer R. Skibbe, Mark Wunderlich, William C. Reinhold, Lei Dong, Chao Shen, Stephen Arnovitz, Bryan Ulrich, Jiuwei Lu, Hengyou Weng, Rui Su, Huilin Huang, Yungui Wang, Chenying Li, Xi Qin, James C. Mulloy, Yi Zheng, Jiajie Diao, Jie Jin, Chong Li, Paul P. Liu, Chuan He, Yuan Chen, Jianjun Chen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Ten-eleven translocation 1 (TET1) is a critical oncoprotein in AML. Here, the authors identify 2 compounds that target the binding of STAT3/5 specifically to the TET1 promoter, inhibiting its expression and AML cell viability.
Externí odkaz:
https://doaj.org/article/a69ded8bba8e453aab53549f9efffc05
Autor:
Geoffrey R. Oxnard, Cloud P. Paweletz, Judy E. Garber, Richard B. Lanman, Martin Gutierrez, Bryan Ulrich, Jayshree Shah, Rebecca J. Nagy, Nora Feeney, Jennifer Heng, Ruthia Chen, Stephen R. Fairclough, Justin I. Odegaard, Ryan S. Alden, Yuebi Hu
Alterations detectable by Guardant360 gene panel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6cdeb8400113c6ae12e533f829a4cf
https://doi.org/10.1158/1078-0432.22466102
https://doi.org/10.1158/1078-0432.22466102
Autor:
Geoffrey R. Oxnard, Cloud P. Paweletz, Judy E. Garber, Richard B. Lanman, Martin Gutierrez, Bryan Ulrich, Jayshree Shah, Rebecca J. Nagy, Nora Feeney, Jennifer Heng, Ruthia Chen, Stephen R. Fairclough, Justin I. Odegaard, Ryan S. Alden, Yuebi Hu
Supplementary legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586ee6b94607ca19b79ab3782efc4cb0
https://doi.org/10.1158/1078-0432.22466099
https://doi.org/10.1158/1078-0432.22466099
Autor:
Geoffrey R. Oxnard, Cloud P. Paweletz, Judy E. Garber, Richard B. Lanman, Martin Gutierrez, Bryan Ulrich, Jayshree Shah, Rebecca J. Nagy, Nora Feeney, Jennifer Heng, Ruthia Chen, Stephen R. Fairclough, Justin I. Odegaard, Ryan S. Alden, Yuebi Hu
Supplemental Figure 1: Case of advanced NSCLC with high level EGFR T790M mutation on plasma next-generation sequencing (NGS). Supplemental Figure 2: Distribution of variant AFs between 25% and 75% across 105 cases of plasma NGS. Supplemental Figure 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ade24f370cae7c099b6aef17fe40180
https://doi.org/10.1158/1078-0432.22466105.v1
https://doi.org/10.1158/1078-0432.22466105.v1
Autor:
Geoffrey R. Oxnard, Cloud P. Paweletz, Judy E. Garber, Richard B. Lanman, Martin Gutierrez, Bryan Ulrich, Jayshree Shah, Rebecca J. Nagy, Nora Feeney, Jennifer Heng, Ruthia Chen, Stephen R. Fairclough, Justin I. Odegaard, Ryan S. Alden, Yuebi Hu
Purpose: Plasma cell-free DNA (cfDNA) analysis is increasingly used clinically for cancer genotyping, but may lead to incidental identification of germline-risk alleles. We studied EGFR T790M mutations in non–small cell lung cancer (NSCLC) toward t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28dc2f4060d8e9e7dc39dd32fde29395
https://doi.org/10.1158/1078-0432.c.6526241
https://doi.org/10.1158/1078-0432.c.6526241
Autor:
Jianjun Chen, Seungpyo Hong, James E. Bradner, Zejuan Li, Jie Jin, Stefan K. Bohlander, Michelle M. Le Beau, Richard A. Larson, Mary Beth Neilly, Shenglai Li, Hao Huang, Yungui Wang, Hengyou Weng, Bryan Ulrich, Kyle Ferchen, Jennifer Strong, Stephen Arnovitz, Sandeep Gurbuxani, Ping Chen, Jun Qi, Tobias Herold, Yang Yang, Chao Hu, Jason Bugno, Xi Jiang
Effects of JQ1 and/or miR-150 nanoparticles on mouse blood cell differentiation four weeks after the last administration of drugs or control (PBS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdaba81a01eee3b139b1621a63ecd9f6
https://doi.org/10.1158/0008-5472.22408808.v1
https://doi.org/10.1158/0008-5472.22408808.v1
Autor:
Jianjun Chen, Seungpyo Hong, James E. Bradner, Zejuan Li, Jie Jin, Stefan K. Bohlander, Michelle M. Le Beau, Richard A. Larson, Mary Beth Neilly, Shenglai Li, Hao Huang, Yungui Wang, Hengyou Weng, Bryan Ulrich, Kyle Ferchen, Jennifer Strong, Stephen Arnovitz, Sandeep Gurbuxani, Ping Chen, Jun Qi, Tobias Herold, Yang Yang, Chao Hu, Jason Bugno, Xi Jiang
Acute myeloid leukemia (AML) is a common and fatal form of hematopoietic malignancy. Overexpression and/or mutations of FLT3 have been shown to occur in the majority of cases of AML. Our analysis of a large-scale AML patient cohort (N = 562) indicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d63575cb63424a9c51da353cdff6b5b
https://doi.org/10.1158/0008-5472.c.6507626
https://doi.org/10.1158/0008-5472.c.6507626
Autor:
Jianjun Chen, Seungpyo Hong, James E. Bradner, Zejuan Li, Jie Jin, Stefan K. Bohlander, Michelle M. Le Beau, Richard A. Larson, Mary Beth Neilly, Shenglai Li, Hao Huang, Yungui Wang, Hengyou Weng, Bryan Ulrich, Kyle Ferchen, Jennifer Strong, Stephen Arnovitz, Sandeep Gurbuxani, Ping Chen, Jun Qi, Tobias Herold, Yang Yang, Chao Hu, Jason Bugno, Xi Jiang
Clinical and molecular characteristics of the AML patients in GSE37642 cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce3345f34d582958dbd0be4cb69ac45
https://doi.org/10.1158/0008-5472.22408817.v1
https://doi.org/10.1158/0008-5472.22408817.v1
Autor:
Jianjun Chen, Seungpyo Hong, James E. Bradner, Zejuan Li, Jie Jin, Stefan K. Bohlander, Michelle M. Le Beau, Richard A. Larson, Mary Beth Neilly, Shenglai Li, Hao Huang, Yungui Wang, Hengyou Weng, Bryan Ulrich, Kyle Ferchen, Jennifer Strong, Stephen Arnovitz, Sandeep Gurbuxani, Ping Chen, Jun Qi, Tobias Herold, Yang Yang, Chao Hu, Jason Bugno, Xi Jiang
Legends for supplemental figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120a2cd51265a905fa166b4015800af8
https://doi.org/10.1158/0008-5472.22408805
https://doi.org/10.1158/0008-5472.22408805
Autor:
Jianjun Chen, Seungpyo Hong, James E. Bradner, Zejuan Li, Jie Jin, Stefan K. Bohlander, Michelle M. Le Beau, Richard A. Larson, Mary Beth Neilly, Shenglai Li, Hao Huang, Yungui Wang, Hengyou Weng, Bryan Ulrich, Kyle Ferchen, Jennifer Strong, Stephen Arnovitz, Sandeep Gurbuxani, Ping Chen, Jun Qi, Tobias Herold, Yang Yang, Chao Hu, Jason Bugno, Xi Jiang
Effects of the nanoparticles on mouse blood cell differentiation two (A) or four (B) weeks after the last administration of nanoparticles or control (PBS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c63cd5c574aeed79c222046c58e541
https://doi.org/10.1158/0008-5472.22408814.v1
https://doi.org/10.1158/0008-5472.22408814.v1