Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Bryan, Forrest"'
Autor:
Peter B. Sampson, Yong Liu, Bryan Forrest, Graham Cumming, Sze-Wan Li, Narendra Kumar Patel, Louise Edwards, Radoslaw Laufer, Miklos Feher, Fuqiang Ban, Donald E. Awrey, Guodong Mao, Olga Plotnikova, Richard Hodgson, Irina Beletskaya, Jacqueline M. Mason, Xunyi Luo, Vincent Nadeem, Xin Wei, Reza Kiarash, Brian Madeira, Ping Huang, Tak W. Mak, Guohua Pan, Henry W. Pauls
Publikováno v:
Journal of Medicinal Chemistry. 58:147-169
Previous publications from our laboratory have introduced novel inhibitors of Polo-like kinase 4 (PLK4), a mitotic kinase identified as a potential target for cancer therapy. The search for potent and selective PLK4 inhibitors yielded (E)-3-((1H-inda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09a88499af90e226793ff88203ec36fb
https://doi.org/10.1021/jm5005336
https://doi.org/10.1021/jm5005336
Autor:
Peter B, Sampson, Yong, Liu, Bryan, Forrest, Graham, Cumming, Sze-Wan, Li, Narendra Kumar, Patel, Louise, Edwards, Radoslaw, Laufer, Miklos, Feher, Fuqiang, Ban, Donald E, Awrey, Guodong, Mao, Olga, Plotnikova, Richard, Hodgson, Irina, Beletskaya, Jacqueline M, Mason, Xunyi, Luo, Vincent, Nadeem, Xin, Wei, Reza, Kiarash, Brian, Madeira, Ping, Huang, Tak W, Mak, Guohua, Pan, Henry W, Pauls
Publikováno v:
Journal of medicinal chemistry. 58(1)
Previous publications from our laboratory have introduced novel inhibitors of Polo-like kinase 4 (PLK4), a mitotic kinase identified as a potential target for cancer therapy. The search for potent and selective PLK4 inhibitors yielded (E)-3-((1Hindaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::160efe8c1bbad6cc1acf1625e82022f2
https://pubmed.ncbi.nlm.nih.gov/25723005
https://pubmed.ncbi.nlm.nih.gov/25723005
Autor:
Peter B. Sampson, Yong Liu, Narendra Kumar Patel, Miklos Feher, Bryan Forrest, Sze-Wan Li, Louise Edwards, Radoslaw Laufer, Yunhui Lang, Fuqiang Ban, Donald E. Awrey, Guodong Mao, Olga Plotnikova, Genie Leung, Richard Hodgson, Jacqueline Mason, Xin Wei, Reza Kiarash, Erin Green, Wei Qiu, Nickolay Y. Chirgadze, Tak W. Mak, Guohua Pan, Henry W. Pauls
Publikováno v:
Journal of medicinal chemistry. 58(1)
Polo-like kinase 4 (PLK4), a unique member of the polo-like kinase family of serine-threonine kinases, is a master regulator of centriole duplication that is important for maintaining genome integrity. Overexpression of PLK4 is found in several human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db45474216f629dfe05ee2b429ad8b7
https://pubmed.ncbi.nlm.nih.gov/24867403
https://pubmed.ncbi.nlm.nih.gov/24867403