Biophysical characterisation of the novel zinc binding property in Suppressor of Fused

Autor: Jabrani, Amira, Makamte, Staëlle, Moreau, Émilie, Gharbi, Yasmine, Plessis, Anne, Bruzzone, Lucia, Sanial, Matthieu, Biou, Valérie

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7 (1), ⟨10.1038/s41598-017-11203-2⟩

Suppressor of Fused (SUFU) is a highly conserved protein that acts as a negative regulator of the Hedgehog (HH) signalling pathway, a major determinant of cell differentiation and proliferation. Therefore, SUFU deletion in mammals has devastating eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::44c3dd01ddf389f5a9c14141a4de85f5
http://link.springer.com/article/10.1038/s41598-017-11203-2