Doxorubicin Effect on Myocardial Metabolism as a Prerequisite for Subsequent Development of Cardiac Toxicity: A Translational 18F-FDG PET/CT Observation

Autor: Bauckneht M 1, Ferrarazzo G 1, Fiz F 1, 2, Morbelli S 1, Sarocchi M 3, Pastorino F 4, Ghidella A 3, Pomposelli E 1, Miglino M 5, Ameri P 3, Emionite L 6, Ticconi F 1, Arboscello E 7, Buschiazzo A 1, Massimelli EA 3, Fiordoro S1, Borra A 1, Cossu V 1, Bozzano A 1, Ibatici A 5, Ponzoni M 4, Spallarossa P 3, Gallamini A 8, Bruzzi P 9, Sambuceti G 10, Marini C 11.

Publikováno v: The Journal of nuclear medicine (1978) 58 (2017): 1638–1645.. doi:10.2967/jnumed.117.191122
info:cnr-pdr/source/autori:Bauckneht M 1, Ferrarazzo G 1, Fiz F 1,2, Morbelli S 1, Sarocchi M 3, Pastorino F 4, Ghidella A 3, Pomposelli E 1, Miglino M 5, Ameri P 3, Emionite L 6, Ticconi F 1, Arboscello E 7, Buschiazzo A 1, Massimelli EA 3, Fiordoro S1, Borra A 1, Cossu V 1, Bozzano A 1, Ibatici A 5, Ponzoni M 4, Spallarossa P 3, Gallamini A 8, Bruzzi P 9, Sambuceti G 10, Marini C 11./titolo:Doxorubicin Effect on Myocardial Metabolism as a Prerequisite for Subsequent Development of Cardiac Toxicity: A Translational 18F-FDG PET%2FCT Observation./doi:10.2967%2Fjnumed.117.191122/rivista:The Journal of nuclear medicine (1978)/anno:2017/pagina_da:1638/pagina_a:1645./intervallo_pagine:1638–1645./volume:58
The Journal of nuclear medicine (1978) 58 (2017): 1638–1645. doi:10.2967/jnumed.117.191122
info:cnr-pdr/source/autori:Matteo Bauckneht 1, Giulia Ferrarazzo 1, Francesco Fiz 1, Silvia Morbelli 1, Matteo Sarocchi 2, Fabio Pastorino 3, Alberto Ghidella 2, Elena Pomposelli 1, Maurizio Miglino 4, Pietro Ameri 2, Laura Emionite 5, Flavia Ticconi 1, Eleonora Arboscello 6, Ambra Buschiazzo 1, Elena Augusta Massimelli 2, Salvatore Fiordoro 1, Anna Borra 1, Vanessa Cossu1, Annalisa Bozzano 1, Adalberto Ibatici 4, Mirco Ponzoni 3, Paolo Spallarossa 2, Andrea Gallamini 7, Paolo Bruzzi 8, Gianmario Sambuceti 1 and Cecilia Marini 9/titolo:Doxorubicin effect on myocardial metabolism as a pre-requisite for subsequent development of cardiac toxicity: a translational 18F-FDG PET%2FCT observation./doi:10.2967%2Fjnumed.117.191122/rivista:The Journal of nuclear medicine (1978)/anno:2017/pagina_da:1638/pagina_a:1645/intervallo_pagine:1638–1645/volume:58

The present translational study aimed to verify whether serial 18F-fluoro-deoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT), predicts doxorubicin cardiotoxicity. Methods: Fifteen athymic mice were treated with intravenous adm

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