Molecular determinants and signaling effects of PKA RIα phase separation.

Autor: Hardy JC; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA; Shu Chien-Gene Lay Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA., Pool EH; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA., Bruystens JGH; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA., Zhou X; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA., Li Q; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA., Zhou DR; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA; Shu Chien-Gene Lay Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA., Palay M; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA., Tan G; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA., Chen L; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA., Choi JLC; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA., Lee HN; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA., Strack S; Department of Pharmacology, University of Iowa, Iowa City, IA 52242, USA., Wang D; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA., Taylor SS; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA., Mehta S; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA., Zhang J; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA; Shu Chien-Gene Lay Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA; Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: jzhang32@health.ucsd.edu.

Publikováno v: Molecular cell [Mol Cell] 2024 Apr 18; Vol. 84 (8), pp. 1570-1584.e7. Date of Electronic Publication: 2024 Mar 26.

From structure to the dynamic regulation of a molecular switch: A journey over 3 decades.

Autor: Taylor SS; Department of Pharmacology, University of California at San Diego, San Diego, California, USA; Department of Chemistry and Biochemistry, University of California at San Diego, San Diego, California, USA. Electronic address: staylor@ucsd.edu., Wu J; Department of Pharmacology, University of California at San Diego, San Diego, California, USA., Bruystens JGH; Department of Pharmacology, University of California at San Diego, San Diego, California, USA., Del Rio JC; Department of Pharmacology, University of California at San Diego, San Diego, California, USA., Lu TW; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, California, USA., Kornev AP; Department of Pharmacology, University of California at San Diego, San Diego, California, USA., Ten Eyck LF; Department of Chemistry and Biochemistry, University of California at San Diego, San Diego, California, USA; San Diego Supercomputer Center, University of California at San Diego, San Diego, California, USA.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100746. Date of Electronic Publication: 2021 May 03.