Abnormal vacuoles distinct from lysosomes in a mouse model of mucopolysaccharidosis type IIIB

Autor: Heard, J.M., Vitry, S., Bruyre, J., Hocquemiller, M., Bigou, S., Nosjean, A., Ausseil, Julie, Colle, Marie-Anne, Prevost, M.C.

Publikováno v: Molecular Genetics and Metabolism
Molecular Genetics and Metabolism, Elsevier, 2010, 99 (2), pp.S20. ⟨10.1016/j.ymgme.2009.10.075⟩
6. Annual World Symposium of the Lysosomal Disease Network
6. Annual World Symposium of the Lysosomal Disease Network, Lysosomal Dis Network., Feb 2010, Miami, United States. 1p
Molecular Genetics and Metabolism, 2010, 99 (2), pp.S20. ⟨10.1016/j.ymgme.2009.10.075⟩

International audience; Progressive accumulation of large intracellular vesicles is a hallmark of cell pathology in lysosomal storage diseases. Accumulating vesicles are commonly identified as crippled lysosomes engorged with incompletely digested ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4689fb5e4097a099880a731706fb76f8
https://hal.inrae.fr/hal-02661892