Nanofractionation Platform with Parallel Mass Spectrometry for Identification of CYP1A2 Inhibitors in Metabolic Mixtures

Autor: Zietek, Barbara M., Mladic, Marija, Bruyneel, Ben, Niessen, Wilfried M.A., Honing, Maarten, Somsen, Govert W., Kool, Jeroen ^*

Publikováno v: In SLAS Discovery March 2018 23(3):283-293

High-performance liquid chromatography–mass spectrometry-based acetylcholinesterase assay for the screening of inhibitors in natural extracts

Autor: de Jong, Camiel F., Derks, Rico J.E., Bruyneel, Ben, Niessen, Wilfried, Irth, Hubertus

Publikováno v: In Journal of Chromatography A 2006 1112(1):303-310

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A decoy-receptor approach using nicotinic acetylcholine receptor mimics reveals their potential as novel therapeutics against neurotoxic snakebite

Autor: Albulescu, Laura Oana, Kazandjian, Taline, Slagboom, Julien, Bruyneel, Ben, Ainsworth, Stuart, Alsolaiss, Jaffer, Wagstaff, Simon C., Whiteley, Gareth, Harrison, Robert A., Ulens, Chris, Kool, Jeroen, Casewell, Nicholas R.

Publikováno v: Frontiers in Pharmacology, 10(JULY):848, 1-15. Frontiers Media S.A.
Albulescu, L O, Kazandjian, T, Slagboom, J, Bruyneel, B, Ainsworth, S, Alsolaiss, J, Wagstaff, S C, Whiteley, G, Harrison, R A, Ulens, C, Kool, J & Casewell, N R 2019, ' A decoy-receptor approach using nicotinic acetylcholine receptor mimics reveals their potential as novel therapeutics against neurotoxic snakebite ', Frontiers in Pharmacology, vol. 10, no. JULY, 848, pp. 1-15 . https://doi.org/10.3389/fphar.2019.00848

Snakebite is a neglected tropical disease that causes 138,000 deaths each year. Neurotoxic snake venoms contain small neurotoxins, including three-finger toxins (3FTxs), which can cause rapid paralysis in snakebite victims by blocking postsynaptic tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0c053057df14ce26a18ff30b63a5b955
https://research.vu.nl/en/publications/f6d99add-c18d-4ff0-8b3d-79c653f056c7

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